Comparison of the Safety and Efficacy of Biodegradable Microneedle Acupuncture and Sterile Acupuncture: study protocol for a prospective, confirmatory, superiority, multicenter, parallel, single-blinded randomized controlled trial [0.03%]
可降解微针与无菌针管安全性和有效性的比较:一项前瞻性、确证性、优效性、多中心、平行、单盲随机对照试验方案
Soo-Yeon Park,Nguyen Cong Duc
Soo-Yeon Park
Objectives: Acupuncture has been widely studied for its safety across multiple countries. Sterile acupuncture (SA), represented by the thumbtack needle, is commonly used due to its ease of application, minimal pain, and a...
Therapeutic Potential of Bee Venom (Apis mellifera intermissa) in Reversing Aniline-Induced Acute Anaemia and Spleen Oxidative Damage in Mice [0.03%]
蜜蜂(Apis mellifera intermissa)毒液治疗潜力可逆转小鼠急性苯胺性溶血和脾脏氧化损伤
Faouzi Dahdouh,Amira Bourouba,Amina Bourouba et al.
Faouzi Dahdouh et al.
Objectives: Aniline, a widely used industrial chemical, is associated with severe anaemia and oxidative damage to the spleen, posing significant health risks through environmental and occupational exposure. Therefore, thi...
In Silico Assessment of Silybum marianum Bioactive Compounds in Prostate Cancer Using Network Pharmacology and Molecular Docking [0.03%]
网络药理学和分子对接在乳蓟活性成分抗前列腺癌的机制研究
Lisa Dal Pozzo,Secondo Scarsella,Maria Abad Arranz et al.
Lisa Dal Pozzo et al.
Objectives: Prostate cancer is a globally prevalent malignancy with rising resistance to conventional therapies. Although awareness and early diagnosis have improved through screening campaigns, there remains a need for a...
Efficacy of an Herbal Vaginal Tablet Containing Oregano and Lemon Balm on Bacterial Vaginosis in Comparison to Metronidazole: a non-inferiority triple-blind active-controlled trial [0.03%]
含有百里香和柠檬香薄荷的中药阴道片治疗细菌性阴道病的有效性和安全性非劣效于甲硝唑:多中心盲法随机对照试验
Elaheh Mesdaghinia,Elham Khosravi,Hossein Akbari et al.
Elaheh Mesdaghinia et al.
Objectives: Bacterial vaginosis (BV) stands as one of the most prevalent causes of vaginal discharge and infection among women of reproductive age. Various medications, including metronidazole, are commonly recommended. F...
Optimizing a Natural Oil-Based Sertaconazole Nitrate Organogel: enhanced antifungal activity through in vitro and in vivo evaluation [0.03%]
优化的天然植物油基赛特康唑硝酸酯有机凝胶剂:体外和体内评估其抗真菌活性增强作用
Piyush Jain,Shashikant Chandrakar,Pushpa Prasad Gupta et al.
Piyush Jain et al.
Objectives: This study aimed to develop and optimize a topical organogel formulation of Sertaconazole nitrate (SN) using Cinnamon oil (CO) to enhance antifungal activity and improve dermal drug delivery. ...
Therapeutic Potential of Methanolic Extract of Areca catechu Nut in Treating Nicotine Use Disorder: evidence from preclinical mouse behavioral models [0.03%]
壳郎果甲醇提取物治疗尼古丁使用障碍的潜力:来自小鼠行为模型的证据
Dnyaneshwari Dhananjay Vibhute,Pallavi Dorik,Anushri Jadhav et al.
Dnyaneshwari Dhananjay Vibhute et al.
Objectives: Arecoline, the main bioactive compound in Areca catechu nut, interacts with nicotinic acetylcholine receptors (α4β2 and α7), suggesting potential in reducing nicotine cravings and withdrawal symptoms. This ...
Bee Products and Traditional Plant Therapies for Wound Care: a comprehensive review of scientific evidence and clinical applications [0.03%]
基于科学证据和临床应用的伤口护理蜜蜂产品及传统植物疗法综合评价
Ahmed A Rawwash,Emad Ahmed Fathy Hussein,Omar Mohammad Atta
Ahmed A Rawwash
Objectives: Natural substances with healing properties, especially medicinal plants and bee-derived products, have been integral to traditional medicine systems for centuries, contributing significantly to wound care. The...
Intradermal Acupuncture for Moderate to Severe Dry Eye Disease: a pilot randomized controlled trial [0.03%]
针灸治疗中重度干眼病的可行性研究:一项随机对照试验
Soo-Yeon Park
Soo-Yeon Park
Objectives: The aim of this study was to evaluate the efficacy of intradermal acupuncture for the treatment of moderate to severe dry eye disease (DED). M...
Inhibition of Adrenergic Agonist-Induced Metastatic Potential in Cancer Cells by an Ethanolic Extract of Lindera aggregata Root Tuber [0.03%]
芸香科褐曲柳干燥根茎乙醇提取物抑制肾上腺素诱导的肿瘤细胞转移潜能
Jae-Hoon Jeong,Shin-Hyung Park
Jae-Hoon Jeong
Objectives: The root tuber of Lindera aggregata (LA) has been traditionally used in Korean medicine to promote qi circulation and alleviate pain. This study investigated the anti-metastatic effects of an ethanolic extract...
Anti-Inflammatory Effect of Urtica urens on LPS-Challenged Keratinocytes [0.03%]
Urtica urens的抗炎作用研究及其对LPS刺激角质形成细胞的影响
Carla Marrassini,María Laura Barreiro Arcos,Laura Cogoi et al.
Carla Marrassini et al.
Objectives: Keratinocytes, the predominant cells in the uppermost layer of the skin, serve as theprimary protection against environmental threats. These cells exhibit activation in the presence of physical trauma, ultravi...