From Control to Conversion: Optimizing Systemic Therapy for Curative-Intent Conversion Surgery in Metastatic Gastric Cancer [0.03%]
从控制到转化:优化系统性治疗以进行具有治愈意图的转化手术以治疗转移性胃癌
Hye Sook Han,Sun Young Rha
Hye Sook Han
Conversion therapy enables curative-intent resection in patients with initially unresectable or metastatic cancers after effective systemic therapy. Recently, advances in systemic therapy with molecular targeted agents and immune checkpoint...
CLDN18.2 in Gastric Cancer: Current Therapeutic Landscape and Future Perspectives [0.03%]
胃癌中的CLDN18.2:当前治疗格局与未来展望
Fei Zhang,Ukyo Okazaki,Izuma Nakayama et al.
Fei Zhang et al.
Claudin 18.2 (CLDN18.2), a tight junction protein selectively expressed in normal gastric epithelium and widely retained during carcinogenesis, has emerged as a promising therapeutic target for advanced gastric cancer (AGC). SPOTLIGHT and G...
Neoadjuvant Chemotherapy for Gastric Cancer: Evolving Approaches and Supporting Evidence [0.03%]
胃癌新辅助化疗:日趋成熟的策略与循证医学证据
Young Jae Kim,Hyung-Don Kim,Jaewon Hyung et al.
Young Jae Kim et al.
Neoadjuvant and perioperative therapy have emerged as promising strategies for managing locally advanced gastric cancer (LAGC). Landmark phase III studies, such as PRODIGY and RESOLVE, have established neoadjuvant chemotherapy as a viable t...
Perioperative Nutritional Treatment for Patients With Gastric Cancer: Focusing on Recent Controversial Issues [0.03%]
胃癌围手术期营养治疗的现状与争议展望
Dongwoo Shin
Dongwoo Shin
Despite the many advances in treatment methods for gastric cancer, it remains a leading cause of cancer-related mortality worldwide, with treatment outcomes intrinsically linked to the nutritional status of the patient. Malnutrition is a fr...
Recent Advances in Endoscopic Submucosal Dissection for Gastric Cancer: Focusing on Expanded Indications and Technological Innovations [0.03%]
内镜黏膜下挖除术治疗胃癌的新进展:注重扩大适应证和技术创新
Waku Hatta,Yohei Ogata,Koya Ogasawara et al.
Waku Hatta et al.
The indications for endoscopic resection (ER) and the criteria for the curability of early gastric cancer (EGC) have been expanding. Among Korea, Japan, and Europe, Korea has the most strictly defined indication for ER, followed by Europe a...
Molecular Imaging in Gastric Cancer: [¹⁸F]FDG and Fibroblast Activation Protein-Targeted PET/CT [0.03%]
胃癌的分子影像:[¹⁸F]FDG和成纤维活化蛋白靶向PET/CT
Chaninart Sakulpisuti,Minseok Suh
Chaninart Sakulpisuti
Gastric cancer remains a major global health burden, and accurate staging and response assessment are essential for optimal management. 2-[¹⁸F]-Fluoro-2-deoxy-D-glucose ([¹⁸F]FDG) positron emission tomography (PET)/computed tomography (...
Isabella Michelon,Anwaar Saeed
Isabella Michelon
Young-onset gastric cancer (YOGC) is an increasingly recognized subtype that challenges traditional assumptions about gastric cancer (GC) biology. Although the overall global incidence of GC continues to decline, the rising burden among ind...
Conor Vaessen,Kieran Redpath,Emily Schulpen et al.
Conor Vaessen et al.
Hereditary diffuse gastric cancer (HDGC) is a dominantly inherited cancer syndrome characterized by the early onset of diffuse gastric cancer (DGC) and lobular breast cancer. HDGC is predominantly caused by germline truncating mutations in ...
Evolving Molecular Subtypes of Gastric Cancer: From Past Classifications to Present Consensus and Future Directions for Precision Therapy [0.03%]
胃癌分子亚型的演变:从过去的分类到现在的共识及未来精准治疗的方向
Ju-Seog Lee
Ju-Seog Lee
Gastric cancer is a biologically heterogeneous disease. The advent of high-throughput multi-omic technologies has revolutionized our understanding of gastric cancer by deconstructing this heterogeneous entity into distinct and more homogene...
Epidemiology of Gastric Cancer in Korea (1999-2022): Incidence, Survival, and 5-Year Conditional Relative Survival [0.03%]
韩国胃癌流行病学(1999-2022):发病率、生存率和五年相对累积生存率
Ki Bum Park,Mee Joo Kang,Johyun Ha et al.
Ki Bum Park et al.
Purpose: This study evaluated long-term trends in gastric cancer epidemiology and survival with a focus on conditional relative survival (CRS). Materials ...