A novel CLRN2 variant: expanding the mutation spectrum and its critical role in isolated hearing impairment [0.03%]
CLRN2的新变异：扩展了突变范围及其在感音神经聋中的关键作用
Farooq Ahmad,Arif Mahmood,Ibrahim Abdullah Almazni et al.
Farooq Ahmad et al.
Background: Biallelic variants in the CLRN2 gene have been reported to cause autosomal recessive profound hearing impairment in humans. CLRN2 belongs to the clarin gene family that encodes a tetraspan protein that contain...
Retrotransposons and DNA transposons: insights into evolutionary genomics [0.03%]
逆转座子和DNA转座子：进化基因组学的启示
Seyoung Mun,Kyudong Han
Seyoung Mun
Transcriptome analysis of tilapia streptococcus agalactiae in response to baicalin [0.03%]
baicalin响应下的鲍鱼链球菌斑马鱼 Transcriptome 分析
Qing-Qin Huang,Shao-Long Liu,Ji-Hui Huang et al.
Qing-Qin Huang et al.
Streptococcus agalactiae (S. agalactiae) is a highly pathogenic bacterial pathogen in aquatic animals. Our previous study has demonstrated the significant inhibitory effect of baicalin on β-hemolytic/cytolytic activity, which is a key viru...
Machine learning identification of NK cell immune characteristics in hepatocellular carcinoma based on single-cell sequencing and bulk RNA sequencing [0.03%]
基于单细胞和批量RNA测序的机器学习识别肝癌中NK细胞免疫特征
Fang Liu,Baohua Mei,Jianfeng Xu et al.
Fang Liu et al.
Background: Hepatocellular carcinoma (HCC) is a highly malignant tumor; however, its immune microenvironment and mechanisms remain elusive. Single-cell sequencing allows for the exploration of immune characteristics withi...
Genetic diversity and structure of Persicaria amphibia (Polygonaceae) in South Korea using genotyping by sequencing [0.03%]
基于测序的基因分型研究韩国Polygonaceae蔊三七的遗传多样性和结构
KyoungSu Choi,Yong Hwang,Jeong-Ki Hong et al.
KyoungSu Choi et al.
Background: Persicaria amphibia, a member of the Polygonaceae family, exists both aquatic and terrestrial forms. It is native to North America, Asia, Europe, and some parts of Africa. ...
Genome-wide identification and expression profiling of the Wnt gene family in three abalone species [0.03%]
皱纹盘鲍、白寿鲍和耳纹魁螺Wnt基因家族的鉴定及表达分析
Qian Zhang,Yangtao Fu,Yanyan Zhang et al.
Qian Zhang et al.
Background: The Wnt gene family plays pivotal roles in a variety of biological processes including cell proliferation and differentiation, apoptosis, and embryonic development. Identifying the Wnt signaling pathway in aba...
Integrated analysis of single-cell RNA-seq and bulk RNA-seq revealed key genes for bone metastasis and chemoresistance in prostate cancer [0.03%]
单细胞RNA测序和批量RNA测序的综合分析揭示了前列腺癌骨转移和耐药的关键基因
Hongai Bai,Zhenyue Li,Yueyue Weng et al.
Hongai Bai et al.
Background: Prostate cancer (PCa) is a serious malignancy. The main causes of PCa aggravation and death are unexplained resistance to chemotherapy and bone metastases. ...
GVAF: generalized, flexible filtering software for annotated variant files [0.03%]
GVAF：通用灵活的注释变异文件过滤软件
Sora Kim,Sungwon Jung
Sora Kim
Background: In the rapidly advancing field of genomics, many tools have been developed to interpret genetic variants using next-generation sequencing (NGS) data. However, these tools often produce annotated variant files ...
Weighted gene co-expression network analysis and identification of ginsenoside biosynthesis candidate genes for ginseng adventitious roots under MeJA treatment [0.03%]
基于茉莉酸甲酯诱导的人参根状茎石斛糖生物合成候选基因的加权基因共表达网络分析
Xiangzhu Li,Yongjun Zheng,Mingming Liu et al.
Xiangzhu Li et al.
Background: Ginseng (Panax ginseng) is an herb with a long history and a wide range of applications. Ginsenoside is one of the most representative and active ginseng compounds, with various pharmacological effects. Theref...
Units containing telomeric repeats are prevalent in subtelomeric regions of a Mesorhabditis isolate collected from the Republic of Korea [0.03%]
含有端粒重复序列的单元在从大韩民国采集的毛首圆线虫亚端粒区域中普遍存在
Seoyeon Kim,Jun Kim
Seoyeon Kim
Background: Mesorhabditis is known for its somatic genome being only a small portion of the germline genome due to programmed DNA elimination. This phenotype may be associated with the maintenance of telomeres at the ends...