Genome-wide analysis of TCP family genes and their constitutive expression pattern analysis in the melon (Cucumis melo) [0.03%]
基于全基因组水平的甜瓜TCP家族基因分析及其启动子的组成型表达模式分析
Md Jahid Hasan Jone,Md Nure Adil Siddique,Manosh Kumar Biswas et al.
Md Jahid Hasan Jone et al.
Background: TCP proteins are plant-specific transcription factors that play essential roles in various developmental processes, including leaf morphogenesis and senescence, flowering, lateral branching, hormone crosstalk,...
Plant cross-fertilization for production of dual-specific antibodies targeting both Ebola virus-like particles and HER2 protein in F1 plants [0.03%]
通过植物杂交授粉在F1植株中产生同时靶向埃博拉病毒样颗粒和人表皮生长因子受体蛋白的双特异性抗体
Daehwan Lee,Hyunjoo Hwang,Yerin Kim et al.
Daehwan Lee et al.
Background: This study explores the cross-fertilization of transgenic tobacco plants to produce dual-specific monoclonal antibodies (mAbs) targeting Ebola virus-like particles and HER2 proteins. We generated F1 plants by ...
Yonjong Heo,Woo-Jin Kim,Yong-Joon Cho et al.
Yonjong Heo et al.
Background: Next-generation sequencing has revolutionized genome science over the last two decades. Indeed, the wealth of sequence information on our genome has deepened our understanding on cancer. Cancer is a genetic di...
Identification of novel CDH23 heterozygous variants causing autosomal recessive nonsyndromic hearing loss [0.03%]
识别出新的CDH23杂合变异引起常染色体隐性非综合征型听力损失
Baoqiong Liao,Wuming Xie,Rutian Liu et al.
Baoqiong Liao et al.
Background: Hearing loss adversely impacts language development, acquisition, and the social and cognitive maturation of affected children. The hearing loss etiology mainly includes genetic factors and environmental facto...
Digital insights into Pseudomonas aeruginosa PBH03: in-silico analysis for genomic toolbox and unraveling cues for heavy metal bioremediation [0.03%]
潘氏克雷伯菌PBH03的数字洞察：基因组工具箱的计算机分析及重金属生物修复线索解析
Himanshu Khandelwal,Sakuntala Mutyala,Da Seul Kong et al.
Himanshu Khandelwal et al.
Background: The genomes of publicly available electroactive Pseudomonas aeruginosa strains are currently limited to in-silico analyses. This study analyzed the electroactive Pseudomonas aeruginosa PBH03 genome using compa...
Identification of SNPs associated with fatty acid contents in mutant soybean lines by a genome-wide association study [0.03%]
利用全基因组关联分析鉴定脂肪酸含量性状的突变体大豆中的SNP标记
Jeong Woo Lee,Jung Min Kim,Dae June Kim et al.
Jeong Woo Lee et al.
Background: Vegetable oils are primarily composed of unsaturated fatty acids. Soybean [Glycine max (L.) Merr.] oil, accounting for 28% of the global production of vegetable oil, contains mainly two saturated fatty acids (...
Prognostic and immunological role of LASP2 in clear cell renal cell carcinoma [0.03%]
LASP2在透明细胞肾细胞癌中的预后和免疫学作用
Libo Chen,Nanhui Chen,Zhouzhou Xie et al.
Libo Chen et al.
Background: Clear cell renal cell carcinoma (ccRCC) represents a common renal carcinoma subtype influenced by the immune microenvironment. LIM and SH3 Protein 2 (LASP2), an actin-binding protein within the nebulin family,...
Baihu Jia Renshen Decoction may improve skeletal muscle and adipose tissue functions of type I diabetic rats by affecting pancreatic β-cell function [0.03%]
白虎加人参汤可能通过影响胰岛β细胞功能改善1型糖尿病大鼠骨骼肌和脂肪组织功能
Shufang Chu,Deliang Liu,Hengxia Zhao et al.
Shufang Chu et al.
Background: Baihu Jia Renshen Decoction (BJRD) is used for diabetes mellitus (DM) management in clinics. Objective: To elucidate the po...
CKAP4 is a potential therapeutic target to overcome resistance to EGFR-TKIs in lung adenocarcinoma [0.03%]
CKAP4是克服EGFR-TKIs耐药性治疗肺腺癌的潜在靶点
Seongeun Song,Sangmyung Rhee
Seongeun Song
Background: Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are standard treatments for non-small cell lung cancer (NSCLC) patients with EGFR mutations; however, drug resistance limits their effica...
Propylparaben-induced endoplasmic reticulum stress triggers G2/M phase cell cycle arrest and initiates caspase-3-dependent apoptosis in human lung cells [0.03%]
对羟基苯甲酸丙酯通过内质网应激诱导人肺细胞G2 / M期阻滞并启动caspase-3依赖性凋亡
Geun-Seup Shin,Yuna Park,Ji-Young Kim et al.
Geun-Seup Shin et al.
Background: Propylparaben (PrP) is commonly used as an antimicrobial agent in food, cosmetics, and pharmaceuticals. While recent studies have shown that PrP exposure can cause various disruptions in cellular physiology, t...