Gene expression profile in ulcerative colitis patients: FOXO4, ALDOB, SLC26A3, SOD2 genes as potential biomarkers [0.03%]
溃疡性结肠炎患者基因表达特征：叉头盒O4、醛缩酶B、溶质载体家族26成员A3和超氧化物歧化酶2基因为潜在生物标志物
Yakup Ülger,Anıl Delik
Yakup Ülger
Background: Ulcerative colitis (UC) is a complex, chronic inflammatory disease that primarily impacts the colon mucosa. One of the key pathological contributors to the development and progression of inflammatory bowel dis...
Report of two coinfections of human adenovirus and sapovirus in patients with acute gastroenteritis from China [0.03%]
来自中国急性胃肠炎患者中两个人腺病毒和札托病毒共感染的报告
Xin Wang,Yaqing He,Mingda Hu et al.
Xin Wang et al.
Background: Coinfections involving multiple diarrheal viruses have gained increasing recognition as a significant cause of acute gastroenteritis in recent years. Understanding the genetic diversity and evolutionary relati...
Ectopic expression of AtMYB115 and AtMYB118 induces green tissue formation in non-green organs of Arabidopsis thaliana [0.03%]
AtMYB115和AtMYB118的异位表达诱导拟南芥非绿色器官中绿色组织的形成
Hyeon-Ung Jang,Sang-Kee Song
Hyeon-Ung Jang
Background: A dominant mutant, green root-dominant (grt-D), which exhibits a green-root phenotype, was identified using the GAL4-UAS activation tagging system in the Q2610 enhancer trap line of Arabidopsis thaliana (Arabi...
RNA-binding protein expression based machine learning model predicts metastasis and treatment outcome of testicular cancer [0.03%]
基于RNA结合蛋白表达的机器学习模型可预测睾丸癌的转移及治疗结果
Lin-Jian Mo,Hai-Qi Liang,Zhen-Yuan Yu et al.
Lin-Jian Mo et al.
Background: RNA-binding proteins (RBPs) are key regulators of cellular transcription and are associated with the occurrence and development of diseases. O...
Alternative splicing of CHI3L1 regulates protein secretion through conformational changes [0.03%]
CHI3L1的可变剪接通过构象变化调节蛋白质分泌
Haesoo Jung,Yong-Eun Kim,Eun-Mi Kim et al.
Haesoo Jung et al.
Background: Alternative splicing (AS) plays a crucial role in regulating protein function through the generation of structurally distinct isoforms. Object...
Whole transcriptome profiling of cardiac injury: insights from a neonatal mouse sepsis model [0.03%]
心脏损伤的全转录组谱分析：来自新生小鼠脓毒症模型的结果
Wenjin Feng,Huanqi Tang,Chengshuai Li et al.
Wenjin Feng et al.
Background: Neonatal sepsis is characterized by an excessive immune response, often leading to multiple organ failure, including cardiac injury, and is a major cause of morbidity and mortality in newborns. Understanding t...
Backtracking identification techniques for predicting unclear bacterial taxonomy at species level: molecular diagnosis-based bacterial classification [0.03%]
基于分子诊断的细菌分类：回溯识别技术在物种水平预测不清的细菌分类学
Yeseul Choi,Jinuk Jeong,Minseo Kim et al.
Yeseul Choi et al.
Bacterial 16S rRNA genes are widely used to classify bacterial communities within interesting environments (e.g., plants, water, human body) because they contain nine hyper-variable regions (V1-V9) reflecting a large number of sequence vari...
Exploring the role of alternative splicing in the pathogenesis of Sjögren's syndrome: identification of novel isoforms associated with salivary gland immune infiltration [0.03%]
探索替代剪接在舍格伦综合征发病机制中的作用：识别与唾液腺免疫浸润相关的新型异构体
Jiaxu Chen,Zhenghao Shi,Luan Xue
Jiaxu Chen
Introduction: Sjögren's syndrome (SS) is an autoimmune disorder affecting exocrine glands, causing dry mouth and eyes, with no effective treatment. While high-throughput sequencing has provided insights into its mechanis...
RepID depletion enhances TWS119-induced erythropoiesis through chromatin reprogramming and transcription factor recruitment [0.03%]
RepID 耗竭通过染色质重新编程和转录因子募集增强 TWS119 诱导的红系发育
Seon-Mi Ok,Jae-Hyun Jo,Hyo Je Cho et al.
Seon-Mi Ok et al.
Background: Erythrocytes, derived from hematopoietic stem cells, are essential for oxygen transport, ensuring survival in all vertebrate animals. The process of erythropoiesis is associated with gene expression changes, b...
Molecular cloning, expression analysis, and functional characterization of Intelectin-1 from Chinese giant salamanders (Andrias davidianus) [0.03%]
中国大鲵（Andrias davidianus）Intectin-1的分子克隆，表达分析和功能特征识别
Haolin Mo,Kexin Liu,Xiaoran An et al.
Haolin Mo et al.
Background: Intelectin (ITLN) plays a pivotal role in innate immunity, inflammatory responses, and tumor progression. However, its physiological roles in caudate amphibians, such as Andrias davidianus, remain elusive. ...