ElF5B as a prognostic biomarker and its correlation with infiltrating immune cells in liver cancer [0.03%]
ELF5B作为预后生物标志物及其与肝癌浸润性免疫细胞的相关性
Tae-Young Kim,An-Na Bae,Jae-Ho Lee
Tae-Young Kim
Multi-omics integration reveals CYTL1 and H6PD as key regulators of tumor metabolism in mesothelioma [0.03%]
多组学整合揭示CYTL1和H6PD在间皮瘤肿瘤代谢中的关键调控作用
Jiao Ma,Huilin Zhang,Luanxue Yu et al.
Jiao Ma et al.
Background: Mesothelioma is a rare and aggressive cancer with limited therapeutic options and poor prognosis. Despite advancements in understanding its molecular mechanisms, effective biomarkers and therapeutic targets re...
The role of RANBP1 in regulating MiRNA expression and apoptosis in breast cancer cells [0.03%]
RANBP1在乳腺癌细胞中调控微小核糖核酸表达和凋亡的作用研究
Pengxia Song,Lin Zhang,Huiping Qiu et al.
Pengxia Song et al.
Background: Breast cancer poses a huge health threat in China. Emerging evidence has indicated that RANBP1 is associated with poor prognosis of breast cancer and has been shown to influence miRNA expression in colorectal ...
Metabolic profiling and genetic tool development in the mucosal bacterium Selenomonas sputigena [0.03%]
黏膜细菌Selenomonas sputigena的代谢轮廓和基因技术开发
Trinh Thi Nguyen,Yu-Kyung Kim,Trang Vu Thien Nguyen et al.
Trinh Thi Nguyen et al.
Background: Selenomonas sputigena is an anaerobic mucosa-associated bacterium with dual roles in human health-acting as a pathobiont in periodontal disease and exhibiting protective effects in allergic airway inflammation...
Targeting the miR-325-3p/GSTP1 axis overcomes paclitaxel resistance in triple-negative breast cancer by inducing ferroptosis [0.03%]
靶向miR-325-3p/GSTP1轴通过诱导铁死亡来克服紫杉醇耐药的三阴性乳腺癌
Huiling Wang,Feng Yang,Yaqin Wu et al.
Huiling Wang et al.
Background: Triple-negative breast cancer (TNBC) is an aggressive subtype with limited treatment options, and paclitaxel resistance remains a major therapeutic challenge. Ferroptosis, an iron-dependent cell death mechanis...
Construction of LncRNA-miRNA-mRNA regulatory network in IgA nephropathy mice model by RNA-sequencing and bioinformatics analysis [0.03%]
基于RNA测序和生物信息学分析的IgA肾病小鼠模型中长链非编码RNA-微小RNA-信使RNA调控网络构建
Wen Jia Zheng,Tao Liu,Xiao Li Zhu et al.
Wen Jia Zheng et al.
Background: Immunoglobulin A nephropathy (IgAN) represents the most prevalent form of primary glomerulonephritis. Long noncoding RNAs (lncRNAs) play critical roles in the initiation and progression of various diseases, in...
Identification of a hypoxia-related gene signature associated with childhood asthma [0.03%]
与儿童哮喘相关的低氧相关基因特征的鉴定
Wenlie Chen,Yuanlu Huang,Li Lei et al.
Wenlie Chen et al.
Background: Hypoxia is a significant manifestation of severe asthma in children. An early and accurate diagnosis is crucial for enhancing treatment outcomes and mitigating long-term complications. This study aims to utili...
NCOA4 inhibits glioma progression by suppressing the Sonic Hedgehog pathway and its overexpression indicates a better glioma prognosis [0.03%]
NCOA4通过抑制Sonic Hedgehog信号通路抑制胶质瘤进展及其过表达提示较好的预后指标
Kaining Liu,Hu Wang,Tian Qiu et al.
Kaining Liu et al.
Background: Nuclear receptor coactivator 4 (NCOA4) is known to be involved in ferroptosis. However, its expression and function in gliomas are still unclear. ...
Regulation of intracellular proliferation of Salmonella typhimurium by CD63 [0.03%]
CD63通过调节胞内菌复制调控鼠伤寒沙门氏菌的感染性
Kwan Sik Park,In Sook Jeon,Jin Tae Hong et al.
Kwan Sik Park et al.
Background: Autophagy is an intracellular degradation process involving the lysosomal breakdown of unnecessary or abnormal cellular components. Targets of autophagy include pathogens, altered organelles, and protein aggre...
Nuclear ribonucleoprotein condensates as platforms for gene expression regulation [0.03%]
核核糖核蛋白凝聚物作为基因表达调控平台
Sunkyung Choi,Kee K Kim
Sunkyung Choi
Liquid-liquid phase separation (LLPS) segregates the eukaryotic nucleus into membraneless ribonucleoprotein (RNP) condensates that orchestrate multiple stages of gene expression. In contrast to cytoplasmic granules, these nuclear assemblies...