Publisher Correction: A chronic whole cigarette smoke extract model reveals redox-mitochondrial adaptation in human lung epithelial and organoid models [0.03%]
出版更正：慢性和整个卷烟烟雾提取模型揭示了人肺上皮和类器官模型中的氧化还原-线粒体适应性
Joo-Eun Lee,Dahye Lee,Jihyun Lee et al.
Joo-Eun Lee et al.
Published Erratum
Experimental & molecular medicine. 2026 Aug 7. DOI:10.1038/s12276-026-01829-6 2026
S100A8/S100A9 released by CD11b+Ly6G+ neutrophils activate MerTKhiLy6clo reparative macrophages to delay denervated muscle atrophy [0.03%]
CD11b+Ly6G+中性粒细胞释放的S100A8/S100A9激活MerTKhiLy6clo修复型巨噬细胞，延缓去神经支配肌肉萎缩
Yaoxian Xiang,Lei Zhu,Zhenwei Qiu et al.
Yaoxian Xiang et al.
Strategies to delay the process of denervated muscle atrophy are limited, in part because the microenvironmental function of the target muscle is not well understood. Immune microenvironment remodelling is one of the main changes of skeleta...
Elizabeth Pan,Alexander Maslov,Jan Vijg
Elizabeth Pan
Age-related genome mosaicism is an inherent feature of multicellularity and genomic instability. It occurs because of DNA mutations, the accumulation of which leads to diverse genomic landscapes across different tissues. DNA mutations in th...
Atsushi Murao,Monowar Aziz,Ping Wang
Atsushi Murao
The gut has a profound influence on the liver through their anatomical connection via the portal vein. During acute inflammation, gut tissue injury leads to increased barrier permeability, allowing the translocation of external contents tha...
Engineered macrophages with IL-10-TLR9 signal switch receptors for reprogramming tumor microenvironment and enhancing antitumor immunity [0.03%]
工程化IL-10-TLR9信号转换受体的巨噬细胞重编程肿瘤微环境并增强抗肿瘤免疫响应
Sijie Wang,Owais Ahmad,Kexin Shui et al.
Sijie Wang et al.
Chimeric antigen receptor (CAR) T cell immunotherapy has achieved remarkable success in hematologic malignancies, prompting the exploration of CAR strategies in solid tumors. Here, we developed a CAR-like signal-switching receptor-macrophag...
Putative glioblastoma origin-like cells in the subventricular zone: isolation and characterization [0.03%]
侧脑室区胶质母细胞瘤起源样细胞的分离及特征分析
Hyeong-Cheol Oh,Ran Joo Choi,Se-Young Jo et al.
Hyeong-Cheol Oh et al.
Glioblastoma (GBM) remains lethal despite maximal therapy. The adult subventricular zone (SVZ), a neural stem-cell niche, has been implicated as a potential site of origin, yet the identity and functional properties of putative GBM origin-l...
Metabolic-epigenetic crosstalk in innate immune cell plasticity within the tumor microenvironment [0.03%]
肿瘤微环境中固有免疫细胞代谢表观遗传相互作用对其可塑性的影响
Junho Noh,Jaehyun Lee,Chaelin You et al.
Junho Noh et al.
The tumor microenvironment exerts profound metabolic and epigenetic pressures that shape the plasticity of innate immune cells, influencing their capacity to promote or suppress tumor progression. Emerging evidence highlights the intricate ...
Metabolic rewiring of the dendritic cell-T cell axis: tumour-derived barriers and therapeutic opportunities [0.03%]
肿瘤来源的树突状细胞-T细胞轴代谢重构：障碍与治疗机会
Minkyu Cho,Minkyung Song
Minkyu Cho
The tumour microenvironment imposes severe metabolic constraints that reshape anti-tumour immunity across the cancer-immunity cycle. Rather than serving merely as passive byproducts of tumour growth, tumour-derived metabolites and nutrient ...
Asymmetric distribution of mitochondrial Ca2+ regulators specifies compartment-specific mitochondrial function and neuronal development [0.03%]
线粒体钙调节蛋白的不对称分布决定线粒体亚区的功能及其神经元发育的作用
Dong Cheol Jang,Su Yeon Kim,Won Seok Kim et al.
Dong Cheol Jang et al.
Neuronal polarization is essential for functional compartmentalization, enabling dendritic synaptic integration and axonal action potential generation. Although structural differences in mitochondria across compartments have been identified...
Macrophage-to-myofibroblast transition-derived itaconate promotes bone metastasis in lung cancer through targeting of HSPA8 [0.03%]
巨噬细胞来源的它酮酸通过靶向HSPA8促进肺癌骨转移
Jin Qian,Zhidan Tan,Jinfeng Wang et al.
Jin Qian et al.
Lung cancer bone metastasis carries a poor prognosis, yet the metabolic determinants driving tumour-stroma crosstalk remain largely elusive. Despite extensive investigations into itaconate, a prominent immunometabolite implicated in macroph...