Nicholas A Lehning,Brad E Morrison
Nicholas A Lehning
Protein degradation is a fundamental feature of cellular life, and malfunction of this process is implicated in human disease. Ubiquitin tagging is the best characterized mechanism of targeting a protein for degradation; however, there are ...
Abdul Karim Haji Dheere,Salvatore Bongarzone,Dinah Shakir et al.
Abdul Karim Haji Dheere et al.
A novel carbon-11 radiolabelling methodology for the synthesis of the dialkylcarbonate functional group has been developed. The method uses cyclotron-produced short-lived [11C]CO2 (half-life 20.4 min) directly from the cyclotron target in a...
Derik R Heiss,Donald W Zehnder nd,David A Jett et al.
Derik R Heiss et al.
Diisopropylfluorophosphate (DFP) is a potent acetylcholinesterase inhibitor commonly used in toxicological studies as an organophosphorus nerve agent surrogate. However, LD50 values for DFP in the same species can differ widely even within ...
Synthesis of Pyrroloquinones via a CAN Mediated Oxidative Free Radical Reaction of 1,3-Dicarbonyl Compounds with Aminoquinones [0.03%]
基于1,3-二羰基化合物与氨基喹喔啉的氧化自由基反应合成吡咯并喹喔啉类化合物
Thao Nguyen,Dwayaja Nadkarni,Shilpa Dutta et al.
Thao Nguyen et al.
Pyrroloquinone ring systems are important structural units present in many biologically active molecules including a number of marine alkaloids. For example, they are found in a series of marine metabolites, such as tsitsikammamines, zyzzya...
Evaluation of Electronic Effects in the Solvolyses of p-Methylphenyl and p-Chlorophenyl Chlorothionoformate Esters [0.03%]
p-甲基苯基和p-氯苯基氯硫羰酸酯溶剂裂解的电子效应评估
Malcolm J D&#x;Souza,Olivia N Hampton,Brett M Sansbury et al.
Malcolm J D&#x;Souza et al.
The solvolyses of p-tolyl chlorothionoformate and p-chlorophenyl chlorothionoformate are studied in a variety of organic mixtures of widely varying nucleophilicity and ionizing power values. This solvolytic data is accumulated at 25.0 °C u...