Michael J Kuhar
Michael J Kuhar
Earlier studies suggesting an involvement of cocaine and amphetamine regulated transcript peptide (CARTp) in the actions of drugs of abuse are confirmed in the most recent publications. This seems especially true for the psychostimulants wh...
CART Peptide Regulates Psychostimulant-Induced Activity and Exhibits a Rate Dependency [0.03%]
率依赖性肽 CART 调节兴奋剂引起的多巴胺能活性
Michael J Kuhar,Martin O Job
Michael J Kuhar
Ethanol-Induced White Matter Atrophy Is Associated with Impaired Expression of Aspartyl-Asparaginyl- β-Hydroxylase (ASPH) and Notch Signaling in an Experimental Rat Model [0.03%]
乙醇诱导的白质萎缩与实验性 rats模型中天冬氨酰天冬氨酰-β-羟化酶（ASPH）和Notch信号转导表达受损有关
Ming Tong,Howard Gonzalez-Navarrete,Tyler Kirchberg et al.
Ming Tong et al.
Alcohol-induced white matter (WM) degeneration is linked to cognitive-motor deficits and impairs insulin/insulin-like growth factor (IGF) and Notch networks regulating oligodendrocyte function. Ethanol downregulates Aspartyl-Asparaginyl-β-...
Substance Abuse Counselors' Recovery Status and Self-Schemas: Preliminary Implications for Empirically Supported Treatment Implementation [0.03%]
substance abuse counselors' recovery status和self-schemas：对基于实证的治疗实施的初步影响
Elizabeth M Nielson
Elizabeth M Nielson
Purpose: The purpose of this paper is to better understand the relationship between substance abuse counselors' personal recovery status, self-schemas, and willingness to use empirically supported treatments for substance...
Cocaine-Like Discriminative Stimulus Effects of Mephedrone and Naphyrone in Mice [0.03%]
梅曲酮和钠吡酮在小鼠身上的可卡因样条件作用效应
Brenda M Gannon,William E Fantegrossi
Brenda M Gannon
Background: In recent years, commercial bath salts products containing synthetic cathinone analogues have emerged as illicit drugs of abuse. These cathinones are structurally similar to the psychostimulants 3,4-methylened...
Sensitization to the motor stimulant effects of 3,4-methylenedioxypyrovalerone (MDPV) and cross-sensitization to methamphetamine in rats [0.03%]
3,4-亚甲二氧基吡罗可福(MDPV)和甲胺蝶呤的致敏作用及两者间的交叉敏感化作用对大鼠的影响
Lucas R Watterson,Peter R Kufahl,Sara B Taylor et al.
Lucas R Watterson et al.
Background: In recent years, there has been a dramatic increase in abuse of the synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV), often in combination with other illicit stimulants. ...
Effects of modafinil and R-modafinil on brain stimulation reward thresholds: implications for their use in the treatment of psychostimulant dependence [0.03%]
莫达非尼和R-莫达非尼对脑刺激奖赏阙值的影响及其在治疗精神兴奋剂依赖中的应用意义
Brian T Burrows,Lucas R Watterson,Meagan A Johnson et al.
Brian T Burrows et al.
Background: Modafinil and its enantiomer R-modafinil are approved for the treatment of various sleep disorders, and may also be efficacious in the treatment of psychostimulant abuse. However, the ability of modafinil and ...
Kamlesh K Bhopale,Shakuntala Kondraganti,Harshica Fernando et al.
Kamlesh K Bhopale et al.
Background: Different strains of rats have been used to study alcoholic liver disease (ALD) while the reason for selecting a particular rat strain was not apparent. ...
Potential Molecular Mechanisms on the Role of the Sigma-1 Receptor in the Action of Cocaine and Methamphetamine [0.03%]
σ-1受体在可卡因和甲基苯丙胺作用中的潜在分子机制
Yuko Yasui,Tsung-Ping Su
Yuko Yasui
The sigma-1 receptor (Sig-1R) is an endoplasmic reticulum membrane protein that involves a wide range of physiological functions. The Sig-1R has been shown to bind psychostimulants including cocaine and methamphetamine (METH) and thus has b...
Michael J Kuhar
Michael J Kuhar