Sanyog Jain,Ijeoma F Uchegbu,Guru Betageri et al.
Sanyog Jain et al.
Abdelbary M A Elhissi,Waqar Ahmed,Israr Ul Hassan et al.
Abdelbary M A Elhissi et al.
Carbon nanotubes (CNTs) have been introduced recently as a novel carrier system for both small and large therapeutic molecules. CNTs can be functionalized (i.e., surface engineered) with certain functional groups in order to manipulate thei...
Glucan particles for macrophage targeted delivery of nanoparticles [0.03%]
葡聚糖颗粒介导的纳米颗粒抗原递呈细胞靶向递送机制研究
Ernesto R Soto,Abaigeal C Caras,Lindsey C Kut et al.
Ernesto R Soto et al.
Glucan particles (GPs) are hollow, porous 2-4 μm microspheres derived from the cell walls of Baker's yeast (Saccharomyces cerevisiae). The 1,3-β-glucan outer shell provides for receptor-mediated uptake by phagocytic cells expressing β-gl...
Safety Evaluation of EXPAREL (DepoFoam Bupivacaine) Administered by Repeated Subcutaneous Injection in Rabbits and Dogs: Species Comparison [0.03%]
EXPAREL（DepoFoam布比卡因）重复皮下注射对兔和狗的安全性评价：种属比较研究
Brigitte M Richard,Douglas E Rickert,Paul E Newton et al.
Brigitte M Richard et al.
EXPAREL (bupivacaine extended-release liposome injection), DepoFoam bupivacaine, is in development for prolonged postsurgical analgesia. Repeat-dose toxicity studies were conducted in rabbits and dogs to compare the potential local and syst...
João Conde,Gonçalo Doria,Pedro Baptista
João Conde
Nanotechnology has prompted new and improved materials for biomedical applications with particular emphasis in therapy and diagnostics. Special interest has been directed at providing enhanced molecular therapeutics for cancer, where conven...
G P Stathopoulos,T Boulikas
G P Stathopoulos
Patented platform technologies have been used for the liposomal encapsulation of cisplatin (Lipoplatin) into tumor-targeted 110 nm (in diameter) nanoparticles. The molecular mechanisms, preclinical and clinical data concerning lipoplatin, a...
Ilaria E Palamà,Mariarosaria Musarò,Addolorata M L Coluccia et al.
Ilaria E Palamà et al.
This pilot study provides the proof of principle for biomedical application of novel polyelectrolyte complexes (PECs) obtained via electrostatic interactions between dextran sulphate (DXS) and poly(allylamine hydrochloride) (PAH). Scanning ...
Juliana Saraiva,Samantha S Marotta-Oliveira,Simone Aparecida Cicillini et al.
Juliana Saraiva et al.
Nitric oxide (NO) is a promising pharmaceutical agent that has vasodilative, antibacterial, and tumoricidal effects. To study the complex and wide-ranging roles of NO and to facilitate its therapeutic use, a great number of synthetic compou...
Modeling drug-carrier interaction in the drug release from nanocarriers [0.03%]
纳米载体药物释放的药物-载体相互作用模型
Like Zeng,Lingling An,Xiaoyi Wu
Like Zeng
Numerous nanocarriers of various compositions and geometries have been developed for the delivery and release of therapeutic and imaging agents. Due to the high specific surface areas of nanocarriers, different mechanisms such as ion pairin...
Poly(amidoamine)-Cholesterol Conjugate Nanoparticles Obtained by Electrospraying as Novel Tamoxifen Delivery System [0.03%]
聚山梨酯80-聚酰胺胺-胆固醇共轭纳米颗粒作为新型他莫昔芬递送系统：旋转电喷雾法制备及其表征研究
R Cavalli,A Bisazza,R Bussano et al.
R Cavalli et al.
A new poly(amidoamine)-cholesterol (PAA-cholesterol) conjugate was synthesized, characterized and used to produce nanoparticles by the electrospraying technique. The electrospraying is a method of liquid atomization that consists in the dis...