Mary H Lien,Vernon K Sondak
Mary H Lien
Basal cell carcinoma (BCC) remains the most common form of nonmelanoma skin cancer (NMSC) in Caucasians, with perhaps as many as 2 million new cases expected to occur in the United States in 2010. Many treatment options, including surgical ...
Basal cell carcinoma: from the molecular understanding of the pathogenesis to targeted therapy of progressive disease [0.03%]
基底细胞癌：从发病机制的分子研究到进展性疾病的靶向治疗
Daniela Göppner,Martin Leverkus
Daniela Göppner
Due to intensified research over the past decade, the Hedgehog (HH) pathway has been identified as a pivotal defect implicated in roughly 25% of all cancers. As one of the most frequent cancer worldwide, the development of Basal cell carcin...
Histopathological variants of cutaneous squamous cell carcinoma: a review [0.03%]
皮肤鳞状细胞癌的组织病理学亚型：综述
Valerie R Yanofsky,Stephen E Mercer,Robert G Phelps
Valerie R Yanofsky
Nonmelanoma skin cancer (NMSC) is the most common form of cancer in the Caucasian population, with squamous cell carcinoma (SCC) accounting for the majority of NMSC-related metastases and death. While most SCC lesions are indolent tumors wi...
Deciphering squamous cell carcinoma using multidimensional genomic approaches [0.03%]
运用多维度基因组方法解析鳞状细胞癌
Ewan A Gibb,Katey S S Enfield,Ivy F L Tsui et al.
Ewan A Gibb et al.
Squamous cell carcinomas (SqCCs) arise in a wide range of tissues including skin, lung, and oral mucosa. Although all SqCCs are epithelial in origin and share common nomenclature, these cancers differ greatly with respect to incidence, prog...
Masahiro Nakayama,Keiji Tabuchi,Yasuhiro Nakamura et al.
Masahiro Nakayama et al.
Basal cell carcinoma (BCC) is a malignant neoplasm derived from nonkeratinizing cells that originate from the basal layer of the epidermis and is the most frequent type of skin cancer in humans, with cumulative exposure to ultraviolet radia...
Inhibition of Epidermal Growth Factor Receptor and PI3K/Akt Signaling Suppresses Cell Proliferation and Survival through Regulation of Stat3 Activation in Human Cutaneous Squamous Cell Carcinoma [0.03%]
表皮生长因子受体和PI3K／Akt信号转导的抑制通过调节Stat3活化而阻断人皮肤鳞状细胞癌的增殖和存活
Toshinori Bito,Nahoko Sumita,Masashi Ashida et al.
Toshinori Bito et al.
Recent studies have emphasized the important role of Stat3 activation in a number of human tumors from the viewpoint of its oncogenic and antiapoptotic activity. In this study, we examined the role and related signaling molecules of Stat3 i...
Two distinct pathways to development of squamous cell carcinoma of the vulva [0.03%]
外阴鳞状细胞癌的两种不同的发展途径
Yutaka Ueda,Takayuki Enomoto,Toshihiro Kimura et al.
Yutaka Ueda et al.
Squamous cell carcinoma (SCC) accounts for approximately 95% of the malignant tumors of the vaginal vulva and is mostly found in elderly women. The future numbers of patients with vulvar SCC is expected to rise, mainly because of the propor...
Assessment of transformed properties in vitro and of tumorigenicity in vivo in primary keratinocytes cultured for epidermal sheet transplantation [0.03%]
体外转化特性及体内外植表皮片诱发肿瘤性的评估研究
A Thépot,A Desanlis,E Venet et al.
A Thépot et al.
Epidermal keratinocytes are used as a cell source for autologous and allogenic cell transplant therapy for skin burns. The question addressed here is to determine whether the culture process may induce cellular, molecular, or genetic altera...
No-needle jet intradermal aminolevulinic Acid photodynamic therapy for recurrent nodular Basal cell carcinoma of the nose: a case report [0.03%]
无针头喷射法表皮给药血红素前身药物光动力疗法治疗复发性鼻基底细胞癌：病例报告
Daniel Barolet,Annie Boucher
Daniel Barolet
Photodynamic therapy (PDT) with aminolevulinic acid (ALA) to treat nodular basal cell carcinoma (BCC) has been shown to be beneficial. The success rate of ALA-PDT in the treatment of nodular BCC is dependent on optimal penetration of the ph...
Case Reports
Journal of skin cancer. 2011:2011:790509. DOI:10.1155/2011/790509 2011
Samet Vasfi Kuvat,Zuhal Gücin,Barış Keklik et al.
Samet Vasfi Kuvat et al.
Basal cell carcinoma is the most commonly seen nonmelanoma skin cancer which is rarely encountered in the childhood period. An 11-year old child was admitted to our clinic due to an erythematous and a slightly pigmented lesion with a 3 × 4...
Case Reports
Journal of skin cancer. 2011:2011:752901. DOI:10.1155/2011/752901 2011