The Role of TGFβ Signaling in Squamous Cell Cancer: Lessons from Mouse Models [0.03%]
TGFβ信号在鳞状细胞癌中的作用:来自小鼠模型的启示
Adam B Glick
Adam B Glick
TGFβ1 is a member of a large growth factor family including activins/inhibins and bone morphogenic proteins (BMPs) that have a potent growth regulatory and immunomodulatory functions in normal skin homeostasis, regulation of epidermal stem...
Omer Sefvan Janjua,Sana Mehmood Qureshi
Omer Sefvan Janjua
Objective. To analyze the pattern of presentation of basal cell carcinoma (BCC) and margin status for excised specimens in the head and neck region. Study Design. Retrospective cross-sectional. Duration of Study. January 2009 to December 20...
Skin reactions and quality of life after x-ray therapy of Basal cell carcinoma [0.03%]
放射治疗基底细胞癌后的皮肤反应及生活质量研究
Jette Skiveren,Maria Rudkjaer Mikkelsen,Helle Daugbjerg et al.
Jette Skiveren et al.
Background. Advanced basal cell carcinoma (BCC) is often treated by surgery or X-ray therapy. The consequences of X-ray therapy on the patients' health-related quality-of-life (HRQOL) have so far not been described. Objectives. To quantify ...
James D Hoerter,Patrick Bradley,Alexandria Casillas et al.
James D Hoerter et al.
What is the cellular origin of melanoma? What role do melanocyte stem cells (MSC) and other melanocyte precursors play in the development of melanoma? Are MSCs and other latent melanocyte precursors more susceptible to solar radiation? Thes...
Principles of Periocular Reconstruction following Excision of Cutaneous Malignancy [0.03%]
恶性皮肤肿瘤切除后的眼睑和眉部再造原则
Scott M Hayano,Katherine M Whipple,Bobby S Korn et al.
Scott M Hayano et al.
Reconstruction of periocular defects following excision of cutaneous malignancy can present difficulties for oculofacial and reconstructive surgeons. The intricate anatomy of the eyelids and face requires precise restoration in order to avo...
Norman Minars,Marianna Blyumin-Karasik
Norman Minars
Background. Basal cell carcinoma (BCC) is the most prevalent skin cancer. Because of its highly vascular characteristic, it is amendable to treatment with pulse dye laser (PDL). The goal of this study is to determine the safety and efficacy...
Topical curcumin-based cream is equivalent to dietary curcumin in a skin cancer model [0.03%]
外用姜黄素软膏与饮食中的姜黄素在皮肤癌模型中具有相同效果
Kunal Sonavane,Jeffrey Phillips,Oleksandr Ekshyyan et al.
Kunal Sonavane et al.
Skin squamous cell carcinoma (SCC), the most common cancer in the USA, is a growing problem with the use of tanning booths causing sun-damaged skin. Antiproliferative effects of curcumin were demonstrated in an aggressive skin cancer cell l...
Thomas Tilling,Ingrid Moll
Thomas Tilling
Merkel cell carcinoma (MCC), a highly aggressive skin tumour with increasing incidence, is associated with the newly discovered Merkel cell polyomavirus (MCPyV). Studies on MCC and MCPyV as well as other risk factors have significantly incr...
e-Health Tools for Targeting and Improving Melanoma Screening: A Review [0.03%]
针对和改善黑色素瘤筛查的电子健康工具:综述研究
Abhilasha Tyagi,Kimberly Miller,Myles Cockburn
Abhilasha Tyagi
The key to improved prognosis for melanoma is early detection and diagnosis, achieved by skin surveillance and secondary prevention (screening). However, adherence to screening guidelines is low, with population-based estimates of approxima...
Genome-wide analysis of gene and protein expression of dysplastic naevus cells [0.03%]
发育性神经细胞基因和蛋白质的基因组广义分析
Linda Gao,Frans A van Nieuwpoort,Jacoba J Out-Luiting et al.
Linda Gao et al.
Cutaneous melanoma, a type of skin tumor originating from melanocytes, often develops from premalignant naevoid lesions via a gradual transformation process driven by an accumulation of (epi)genetic lesions. These dysplastic naevi display a...