Rising incidence of mucosal melanoma of the head and neck in the United States [0.03%]
美国头颈部黏膜黑色素瘤发病率升高
David M Marcus,Rebecca P Marcus,Roshan S Prabhu et al.
David M Marcus et al.
Background. While it is established that the incidence of cutaneous melanoma has risen over time in the United States, the incidence trend for mucosal melanoma of the head and neck (MMHN) is unknown. Methods. We used the Surveillance, Epide...
H3K79me3T80ph is a Novel Histone Dual Modification and a Mitotic Indicator in Melanoma [0.03%]
组蛋白新修饰H3K79me3T80ph及其作为黑色素瘤有丝分裂指示物的作用
Danielle R Martinez,Hunter W Richards,Qiushi Lin et al.
Danielle R Martinez et al.
The current study characterizes the mitosis-associated histone dual modification on the core of histone H3: trimethylation of histone H3 lysine 79 and simultaneous phosphorylation of H3 threonine 80 (H3K79me3T80ph). Through the use of prote...
Melanoma in organ transplant recipients: incidence, outcomes and management considerations [0.03%]
器官移植受者黑色素瘤的发病率、结局及诊治要点
Faisal R Ali,John T Lear
Faisal R Ali
The incidence of melanoma continues to increase year on year. With better surgical techniques and medical management, greater numbers of organ transplants are being performed annually with much longer graft survival. The authors review our ...
Justin Lee,Ian Poon,Judith Balogh et al.
Justin Lee et al.
Merkel cell carcinoma of the head and neck (MCCHN) presents a clinical challenge due to its aggressive natural history, unpredictable lymphatic drainage, and high degree of treatment related morbidity. Histological examination of the region...
Nanobiotechnological Nanocapsules Containing Polyhemoglobin-Tyrosinase: Effects on Murine B16F10 Melanoma Cell Proliferation and Attachment [0.03%]
含多聚血红素-酪氨酸酶的纳米胶囊的纳异生物技术学效应：对小鼠B16F10黑色素瘤细胞增殖和粘附的影响
Yun Wang,Thomas M S Chang
Yun Wang
We have reported previously that daily intravenous infusions of a soluble nanobiotechnological complex, polyhemoglobin-tyrosinase [polyHb-Tyr], can suppress the growth of murine B16F10 melanoma in a mouse model. In order to avoid the need f...
Germ cell proteins in melanoma: prognosis, diagnosis, treatment, and theories on expression [0.03%]
黑色素瘤中的生殖细胞蛋白：预后、诊断、治疗和表达理论
Ashley M Rosa,Nitika Dabas,Diana M Byrnes et al.
Ashley M Rosa et al.
Germ cell protein expression in melanoma has been shown to correlate with malignancy, severity of disease and to serve as an immunologic target for therapy. However, very little is known about the role that germ cell proteins play in cancer...
Pulsed dye laser does not seem as effective as red light in Basal cell carcinoma mal-pdt: a small pilot study [0.03%]
脉冲染料激光与红色光相比在基底细胞癌 MAL-PDT 中效果较差：一项小型初步研究
M Fernández-Guarino,A Harto,P Jaén
M Fernández-Guarino
Multiple light sources can be used for photodynamic therapy (PDT) with good results, but there are few comparative studies. This study compares the efficacy of treatment of basal cell carcinoma with PDT and two light sources, the non-cohere...
Jeremy Croker,Bryan Burmeister,Matthew Foote
Jeremy Croker
Neurotropic melanoma is a rare subtype of cutaneous malignant melanoma. Compared with conventional melanoma, it is more locally aggressive with an increased tendency for local recurrence but less likely for nodal or distant metastases. Thes...
Nitika Dabas,Diana M Byrnes,Ashley M Rosa et al.
Nitika Dabas et al.
Early diagnosis gives melanoma patients the best chance for long term survival. However discrimination of an early melanoma from an unusual/atypical benign nevus can represent a significant challenge. There are no current pathological marke...
Multiple roles for VEGF in non-melanoma skin cancer: angiogenesis and beyond [0.03%]
血管内皮生长因子在非黑色素瘤皮肤癌中的多种作用：血管生成及其他作用
Kelly E Johnson,Traci A Wilgus
Kelly E Johnson
Vascular endothelial growth factor (VEGF) is known to play a critical role in the development of non-melanoma skin cancers. VEGF is a potent pro-angiogenic factor and it is elevated in mouse and human skin tumors. The use of transgenic and ...