Fatigue, tiredness, lack of energy, and sleepiness in multiple sclerosis patients referred for clinical polysomnography [0.03%]
多发性硬化患者进行临床多项睡眠图检查的疲劳、乏力、无能量和嗜睡症状
Tiffany J Braley,Ronald D Chervin,Benjamin M Segal
Tiffany J Braley
Objectives. To assess the relationship between nocturnal polysomnographic (PSG) findings and a group of key self-reported symptoms-fatigue, tiredness, lack of energy, and sleepiness-among sleep-laboratory referred patients with and without ...
The diagnostic and prognostic value of neurofilament heavy chain levels in immune-mediated optic neuropathies [0.03%]
自身免疫性视神经病变患者中神经丝蛋白重链的诊断及预后价值
Axel Petzold,Gordon T Plant
Axel Petzold
Background. Loss of visual function differs between immune-mediated optic neuropathies and is related to axonal loss in the optic nerve. This study investigated the diagnostic and prognostic value of a biomarker for neurodegeneration, the n...
Woojun Kim,Su-Hyun Kim,So-Young Huh et al.
Woojun Kim et al.
Neuromyelitis optica (NMO) is an idiopathic inflammatory syndrome of the central nervous system that is characterized by severe attacks of optic neuritis (ON) and myelitis. Until recently, NMO was considered a disease without brain involvem...
Quantitative magnetic resonance imaging of cortical multiple sclerosis pathology [0.03%]
定量磁共振成像评估皮层多发性硬化病理学
Christine L Tardif,Barry J Bedell,Simon F Eskildsen et al.
Christine L Tardif et al.
Although significant improvements have been made regarding the visualization and characterization of cortical multiple sclerosis (MS) lesions using magnetic resonance imaging (MRI), cortical lesions (CL) continue to be under-detected in viv...
Eric Thouvenot,Frédéric Mura,Marie De Verdal et al.
Eric Thouvenot et al.
Background. Uveitis is 20 times more frequent in multiple sclerosis (MS) patients than in the general population. Methods. A retrospective study of local multiple sclerosis (n = 700) and uveitis cohorts (n = 450) described the ophthalmologi...
Samantha M Kimball,Heather E Hanwell
Samantha M Kimball
Induced brain plasticity after a facilitation programme for autobiographical memory in multiple sclerosis: a preliminary study [0.03%]
多发性硬化症自主传记记忆促进方案后的诱导大脑可塑性：一项初步研究
Alexandra Ernst,Anne Botzung,Daniel Gounot et al.
Alexandra Ernst et al.
This preliminary study tackles the assessment and treatment of autobiographical memory (AbM) in relapsing-remitting multiple sclerosis (RR-MS) patients. Our aim was to investigate cerebral activation changes, following clinical improvement ...
Massimiliano Calabrese,Dario Seppi,Eleonora Cocco et al.
Massimiliano Calabrese et al.
Background. Although grey matter pathology is a relevant aspect of multiple sclerosis (MS) both with physical and cognitive rebounds, its pathogenesis is still under investigation. To what extent the familial and sporadic cases of MS differ...
Absence of Multiple Sclerosis and Demyelinating Diseases among Lacandonians, a Pure Amerindian Ethnic Group in Mexico [0.03%]
墨西哥拉卡诺迪安人（纯粹的美洲原住民部落）中无多发性硬化症及其他脱髓鞘疾病
Jose Flores,Silvia González,Ximena Morales et al.
Jose Flores et al.
Multiple Sclerosis (MS) is a highly polymorphic disease characterized by different neurologic signs and symptoms. In MS, racial and genetic factors may play an important role in the geographic distribution of this disease. Studies have repo...
Combination therapy of interferon Beta-1b and tacrolimus: a pilot safety study [0.03%]
干扰素Beta-1b与他克莫司联合治疗的初步安全性研究
F Jacques,I Gaboury,S Christie et al.
F Jacques et al.
Tacrolimus is a calcineurin inhibitor which works to induce immune suppression by preventing cytokine transcription and lymphocyte activation. Combining the immunomodulator interferon beta-1b (Betaseron) with the immunosuppressant tacrolimu...