Morbidity and mortality of COVID-19 negatively associated with the frequency of consanguineous marriages, an ecologic study [0.03%]
一项生态学研究:COVID-19的病死率与近亲婚配频率负相关
Mostafa Saadat
Mostafa Saadat
Background: Union between second cousins and closer relatives is called consanguineous marriage. Consanguineous marriage is associated with increased risk of autosomal recessive diseases and several multifactorial traits....
Understanding the pivotal roles of ACE2 in SARS-CoV-2 infection: from structure/function to therapeutic implication [0.03%]
了解ACE2在SARS-CoV-2感染中的关键作用:从结构/功能到治疗意义
Amir Pouremamali,Abouzar Babaei,Somayeh Shatizadeh Malekshahi et al.
Amir Pouremamali et al.
In December 2019, a novel respiratory tract infection, from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was detected in China that rapidly spread around the world. This virus possesses spike (S) glycoproteins on the surfac...
Investigating expressed RNA variants that are related to disease severity in SARS-CoV-2-infected patients with mild-to-severe disease [0.03%]
研究SARS-CoV-2感染患者(从轻度到重度)中与疾病严重程度相关的表达RNA变异体
Javan Okendo,David Okanda
Javan Okendo
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to be a significant public health challenge globally. SARS-CoV-2 is a novel virus, and the understanding of what constitutes expressed RNA...
Virtual screening and molecular dynamic simulations of the antimalarial derivatives of 2-anilino 4-amino substituted quinazolines docked against a Pf-DHODH protein target [0.03%]
基于Pf-DHODH靶点的2-芳氨基-4-氨基取代喹唑啉抗疟衍生物的虚拟筛选及分子动力学模拟研究
Zakari Yau Ibrahim,Adamu Uzairu,Gideon Adamu Shallangwa et al.
Zakari Yau Ibrahim et al.
Background: The processes of drug development and validation are too expensive to be subjected to experimental trial and errors. Hence, the use of the insilico approach becomes imperative. To this effect, the drug-likenes...
A systems biology approach for investigating significantly expressed genes among COVID-19, hepatocellular carcinoma, and chronic hepatitis B [0.03%]
一种系统生物学方法,用于调查COVID-19、肝细胞癌和慢性乙肝之间差异表达基因
Babak Sokouti
Babak Sokouti
Background: Worldwide, COVID-19's death rate is about 2%, considering the incidence and mortality. However, the information on its complications in other organs, specifically the liver and its disorders, is limited in mil...
Oral cavity infection by the SARS-CoV-2: emphasizing the essence of masking and peptide therapeutics [0.03%]
新型冠状病毒口腔感染:强调佩戴口罩和多肽药物治疗的重要性
Glory Omini Ibiang,Joseph Malachi,Mercy Omini Ibiang et al.
Glory Omini Ibiang et al.
The SARS-CoV-2 has infected many people globally with the ravaging COVID-19; a disease, which has become challenging for every aspect of modern healthcare. The saliva and oral mucosa are sites of high risk for increased viral loads, and asi...
Miapeh Kous Gonlepa,Olayemi Hafeez Rufai,Chidinmma Grace Ofuonye et al.
Miapeh Kous Gonlepa et al.
Hematological indices in pediatric patients with acyanotic congenital heart disease: a cross-sectional study of 248 patients [0.03%]
248例无紫绀型先天性心脏病患儿的血液学指标分析
Hanieh Mohammadi,Behzad Mohammadpour Ahranjani,Ehsan Aghaei Moghadam et al.
Hanieh Mohammadi et al.
Background: Congenital heart disease CHD is a significant cause of mortality and morbidity in children worldwide. Patients with congenital heart disease may develop hematological problems, including thrombocytopenia and n...
Lysosomal storage diseases in the era of COVID-19: a report of an Egyptian case of alpha-fucosidosis and a summary of the lysosomal storage diseases-COVID-19 relationship [0.03%]
COVID-19时代的溶酶体贮积病:一例埃及α岩藻糖苷酶病患者的报告及溶酶体贮积病与COVID-19关系的综述
Heba Saed El-Amawy,Heba Dawoud
Heba Saed El-Amawy
Background: We present a case of alpha-fucosidosis, a lysosomal storage disorder, from Egypt. The report also includes a brief review of the COVID-19 and lysosomal storage diseases relationship. ...
Analysis of real-time PCR Melanocortin 3 (MC3R) gene expression to identify new biomarkers inflammation in tuberculosis [0.03%]
实时荧光定量PCR分析黑皮质素受体3(MC3R)基因表达寻找结核病新的炎症标志物研究分析
Andi Tenriola,Najdah Hidayah,Subair et al.
Andi Tenriola et al.
Background: Diagnosis of tuberculosis (TB) in the era of technological sophistication requires accuracy and speed to provide as much information as possible so that TB treatment can be carried out quickly and precisely. N...