High prevalence and molecular spectrum of β-thalassemia trait in Haripur and Abbottabad districts of Pakistan: implications for regional carrier screening programs [0.03%]
巴基斯坦哈里普尔和阿伯塔巴德地区β-地中海贫血高携带率及基因型分布：对区域携带者筛查项目的启示
Ehtisham Ul Haq,Asma Naeem,Usman Ayub Awan et al.
Ehtisham Ul Haq et al.
Background: β-thalassemia is a common autosomal recessive blood disorder caused by mutations in the β-globin gene, with highly variable carrier frequencies across different regions. In Pakistan, cultural practices such ...
Polymorphism rs259983 of the ZNF831 gene is associated with the risk of anemia in pregnant women with gestational diabetes [0.03%]
妊娠糖尿病妇女缺铁性贫血的易感基因ZNF831 rs259983多态性研究
Nataliia Karpova,Olga Dmitrenko,Ekaterina Arshinova et al.
Nataliia Karpova et al.
Background: Iron deficiency is a cause of anemia in pregnant women. Iron metabolism is closely related to zinc levels and the state of zinc-containing proteins. Zinc-binding proteins (ZNFs) can also bind other metal ions....
TaqI polymorphism of the VDR gene: aspects related to the clinical behavior of COVID-19 in Cuban patients [0.03%]
COVID-19患者的维生素D受体基因TaqI多态性及其临床行为特征分析
Estela Morales Peralta,Yaíma Zúñiga Rosales,Teresa Collazo Mesa et al.
Estela Morales Peralta et al.
Purpose: To determine the relationship between the genotypes of the TaqI polymorphism of VDR gene and the clinical forms of COVID-19 in Cuban patients. Me...
Coronavirus disease 19 and risk of hyperglycemia among Iraqi patients [0.03%]
2019冠状病毒病在伊拉克患者的高血糖风险中的作用
Ali H Ad&#x;hiah,Noor T Al-Bayatee,Aeshah A Ahmed
Ali H Ad&#x;hiah
A cross-sectional observational study was conducted on 213 patients with COVID-19 who did not have a clinical history of diabetes at hospital admission. One week after hospitalization, they were stratified by random blood glucose levels. It...
Characterization of the SARS-CoV-2 coronavirus X4-like accessory protein [0.03%]
SARS-CoV-2冠状病毒X4_like辅助蛋白的特征分析
Olanrewaju Ayodeji Durojaye,Nkwachukwu Oziamara Okoro,Arome Solomon Odiba
Olanrewaju Ayodeji Durojaye
Background: The novel coronavirus SARS-CoV-2 is currently a global threat to health and economies. Therapeutics and vaccines are in rapid development; however, none of these therapeutics are considered as absolute cure, a...
Molecular analysis of CFTR gene mutations among Iraqi cystic fibrosis patients [0.03%]
伊拉克囊性纤维化患者中CFTR基因突变的分子分析
Asal Gailan Abdul-Qadir,Bassam Musa Al-Musawi,Rabab Farhan Thejeal et al.
Asal Gailan Abdul-Qadir et al.
Background: Cystic fibrosis (CF) is an autosomal recessive multisystem disease that results from mutation(s) of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. More than 2100 mutations and polymorphis...
Susceptibility to the novel coronavirus disease (COVID-19) is associated with ABO and Rh blood groups: a case-control study from Afghanistan [0.03%]
ABO和Rh血型与新型冠状病毒肺炎(COVID-19)的易感性有关：来自阿富汗的一项病例对照研究
Khyber Saify,Mohammad Sarwar Alborz,Mostafa Saadat
Khyber Saify
Background: There are preliminary studies about the association between COVID-19 and ABO phenotypes and the results are controversial. There are only two studies which investigated the association of Rh blood groups in ad...
Association between ABO blood groups and susceptibility to COVID-19: profile of age and gender in Iraqi patients [0.03%]
ABO血型与伊拉克新冠肺炎患者易感性及相关年龄和性别特征的关系研究
Ali H Ad&#x;hiah,Maha H Abdullah,Mustafa Y Alsudani et al.
Ali H Ad&#x;hiah et al.
Background: A case-control study was performed to examine age, gender, and ABO blood groups in 1014 Iraqi hospitalized cases with Coronavirus disease 2019 (COVID-19) and 901 blood donors (control group). The infection was...
Mayank Chaudhary
Mayank Chaudhary
Background: Angiotensin-converting enzyme 2 (ACE2) is a metallopeptidase that primarily functions as a negative regulator of renin angiotensin system (RAS) by converting angiotensin II (Ang II) to angiotensin 1-7. Contrar...
Understanding the genetic determinant of severity in viral diseases: a case of SARS-Cov-2 infection [0.03%]
理解病毒性疾病严重程度的遗传决定因素——以SARS-CoV-2感染为例
Babayemi Olawale Oladejo,Covenant Femi Adeboboye,Tinuola Tokunbo Adebolu
Babayemi Olawale Oladejo
Background: Numerous research studies have identified specific human gene variants that affect enhanced susceptibility to viral infections. More recently is the current pandemic where the SARS-CoV-2 infection has shown a ...