Contributory role of SARS-CoV-2 genomic variations and life expectancy in COVID-19 transmission and low fatality rate in Africa [0.03%]
SARS-CoV-2基因组变异和人均寿命对非洲新冠传播及低死亡率的贡献作用分析
Olabode E Omotoso
Olabode E Omotoso
Background: The novel coronavirus disease (COVID-19) has claimed lots of lives, posing a dire threat to global health. It was predicted that the coronavirus outbreak in the African population would be very lethal and resu...
Evaluating of the association between ABO blood groups and coronavirus disease 2019 (COVID-19) in Iraqi patients [0.03%]
评估伊拉克新冠肺炎患者ABO血型与冠状病毒疾病2019(COVID-19)关联性研究
Ali H Ad&#x;hiah,Risala H Allami,Raghdan H Mohsin et al.
Ali H Ad&#x;hiah et al.
Background: Susceptibility to the pandemic coronavirus disease 2019 (COVID-19) has recently been associated with ABO blood groups in patients of different ethnicities. This study sought to understand the genetic associati...
An in silico LLPS perturbation approach in the design of a novel SARS-CoV-2 spike receptor-binding domain inhibitor [0.03%]
一种新的SARS-CoV-2刺突受体结合结构域抑制剂的计算机扰动相分离设计方法研究
Olanrewaju Ayodeji Durojaye,Divine Mensah Sedzro,Talifhani Mushiana et al.
Olanrewaju Ayodeji Durojaye et al.
The reversible process where a homogenous fluid de-mixes into two distinctively separate liquid phases is referred to as LLPS (Liquid-liquid phase separation). The resulting liquid is made up of one dilute phase and one condensed phase. An ...
The morbidity and mortality of COVID-19 are correlated with the Ile105Val glutathione S-transferase P1 polymorphism [0.03%]
COVID-19的发病率和死亡率与谷胱甘肽S转移酶P1基因多态性有关
Mostafa Saadat
Mostafa Saadat
Background: Oxidative stress is an important issue in coronavirus disease 2019 (COVID-19). Considering that glutathione S-transferase P1 (GSTP1) is involved in cellular detoxification, it may play an important role in sus...
Low iron mitigates viral survival: insights from evolution, genetics, and pandemics-a review of current hypothesis [0.03%]
低铁缓解病毒存活：从进化、遗传和大流行病中获得的见解——当前假设综述
Rahma Menshawey,Esraa Menshawey,Ayman H K Alserr et al.
Rahma Menshawey et al.
Background: Upon re-examination of our human history, evolutionary perspectives, and genetics, a prevailing iron deficiency phenotype appears to have evolved to protect the human race from extinction. ...
Potential therapeutic target identification in the novel 2019 coronavirus: insight from homology modeling and blind docking study [0.03%]
基于同源建模和盲对接的新型冠状病毒潜在治疗靶点识别研究
Olanrewaju Ayodeji Durojaye,Talifhani Mushiana,Henrietta Onyinye Uzoeto et al.
Olanrewaju Ayodeji Durojaye et al.
Background: The 2019-nCoV which is regarded as a novel coronavirus is a positive-sense single-stranded RNA virus. It is infectious to humans and is the cause of the ongoing coronavirus outbreak which has elicited an emerg...
An in silico epitope-based peptide vaccine design against the 2019-nCoV [0.03%]
基于抗原表位的2019-nCoV肽疫苗的计算机设计研究
Olanrewaju Ayodeji Durojaye,Talifhani Mushiana,Samuel Cosmas et al.
Olanrewaju Ayodeji Durojaye et al.
Design of a multi-epitope-based peptide vaccine against the S and N proteins of SARS-COV-2 using immunoinformatics approach [0.03%]
基于免疫信息学方法设计针对SARS-COV-2的S和N蛋白的多表位肽疫苗
Arian Karimi Rouzbahani,Farnaz Kheirandish,Seyedeh Zeinab Hosseini
Arian Karimi Rouzbahani
Background: As the new pandemic created by COVID-19 virus created the need of rapid acquisition of a suitable vaccine against SARS-CoV-2 to develop Immunity and to reduce the mortality, the aim of this study was to identi...
Implication of single nucleotide polymorphisms in Interleukin-10 gene (rs1800896 and rs1800872) with severity of COVID-19 [0.03%]
IL-10基因多态性与新冠肺炎病情严重程度相关性的研究进展
Saliha Rizvi,S Mohd Shiraz Rizvi,Syed Tasleem Raza et al.
Saliha Rizvi et al.
Background: Coronavirus disease 2019 (COVID-19) is an ongoing pandemic which has emerged as a new challenge for the medical sciences. Severity of COVID-19 is mostly determined with overexpressed proinflammatory cytokines ...
Pathway analysis of smoking-induced changes in buccal mucosal gene expression [0.03%]
基于口腔黏膜基因表达变化的吸烟途径分析
Anas Khaleel,Bayan Alkhawaja,Talal Salem Al-Qaisi et al.
Anas Khaleel et al.
Background: Cigarette smoking is the leading preventable cause of death worldwide, and it is the most common cause of oral cancers. This study aims to provide a deeper understanding of the molecular pathways in the oral c...