Urinary 20-HETE: A prospective Non-Invasive prognostic and diagnostic marker for diabetic kidney disease [0.03%]
尿液20-HETE:糖尿病肾脏疾病的前瞻性无创诊断和预后标志物
Pamela Houeiss,Rachel Njeim,Hani Tamim et al.
Pamela Houeiss et al.
Introduction: The identification and validation of a non-invasive prognostic marker for early detection of diabetic kidney disease (DKD) can lead to substantial improvement in therapeutic decision-making. ...
Genomic signatures underlying the oogenesis of the ectoparasitic mite Varroa destructor on its new host Apis mellifera [0.03%]
Varroa破坏者在日本蜜蜂上的寄生生殖的转录组和小干扰RNA组分析
Huoqing Zheng,Shuai Wang,Yuqi Wu et al.
Huoqing Zheng et al.
Introduction: Host shift of parasites may have devastating effects on the novel hosts. One remarkable example is that of the ectoparasitic mite Varroa destructor, which has shifted its host from Eastern honey bees (Apis c...
Identification and validation of functional roles for three MYC-associated genes in hepatocellular carcinoma [0.03%]
三种MYC相关基因在肝细胞癌中功能作用的鉴定与验证
Sha Li,Pei Xue,Xun Diao et al.
Sha Li et al.
Background: Aberrations in MYC underlie a large proportion of liver hepatocellular carcinoma (LIHC) cases; however, MYC is difficult to target because of its undruggable structure. We aimed to uncover MYC-associated molec...
Contribution of Nischarin/IRAS in CNS development, injury and diseases [0.03%]
Nischarin/IRAS在中枢神经系统发育、损伤及疾病中的作用
Peijie Zheng,Chenshu Pan,Chuntao Zhou et al.
Peijie Zheng et al.
Background: Murine Nischarin and its human homolog IRAS are scaffold proteins highly expressed in the central nervous system (CNS). Nischarin was initially discovered as a tumor suppressor protein, and recent studies have...
Jun-Yu Deng,Xing-Qian Wu,Wen-Jie He et al.
Jun-Yu Deng et al.
Background: Poor wound healing is a significant complication of diabetes, which is commonly caused by neuropathy, trauma, deformities, plantar hypertension and peripheral arterial disease. Diabetic foot ulcers (DFU) are d...
Single-cell analysis reveals lysyl oxidase (Lox)+ fibroblast subset involved in cardiac fibrosis of diabetic mice [0.03%]
单细胞分析揭示糖尿病小鼠心脏纤维化相关的Lysyl Oxidase(Lox)+亚群纤维母细胞
Heyangzi Li,Xiaoqing Zhu,Xi Cao et al.
Heyangzi Li et al.
Introduction: Myocardial fibrosis and cardiac dysfunction are the main characteristics of diabetic heart disease. However, the molecular mechanisms underlying diabetic myocardial fibrosis remain unclear. ...
A spatiotemporal drug release scaffold with antibiosis and bone regeneration for osteomyelitis [0.03%]
一种用于骨髓炎治疗的兼具抗菌和促骨再生的时空控释载体支架
Shengda Wu,Yang Shuai,Guowen Qian et al.
Shengda Wu et al.
Introduction: Scaffolds loaded with antibacterial agents and osteogenic drugs are considered essential tools for repairing bone defects caused by osteomyelitis. However, the simultaneous release of two drugs leads to prem...
Ferroptosis in acute kidney injury following crush syndrome: A novel target for treatment [0.03%]
挤压综合征急性肾损伤中的铁死亡:一种潜在治疗靶点
Ou Qiao,Xinyue Wang,Yuru Wang et al.
Ou Qiao et al.
Background: Crush syndrome (CS) is a kind of traumatic and ischemic injury that seriously threatens life after prolonged compression. It is characterized by systemic inflammatory reaction, myoglobinuria, hyperkalemia and ...
Celery soluble dietary fiber antagonizes flavonoids ameliorative effect on dextran-sodium-sulfate-induced colitis in mice [0.03%]
葵菜可溶性膳食纤维对抗黄酮类化合物对小鼠葡聚糖硫酸钠诱导结肠炎的改善作用
Hui Wang,Xiaojun Huang,Shengkun Xia et al.
Hui Wang et al.
Introduction: Dietary fiber and flavonoids are promising drugs reported in the treatment of inflammatory bowel disease (IBD). However, it is unclear the interaction between dietary fiber and flavonoids in gut health. ...
Lemin Peng,Zhennao Cai,Ali Asghar Heidari et al.
Lemin Peng et al.
Introduction: The main feature selection methods include filter, wrapper-based, and embedded methods. Because of its characteristics, the wrapper method must include a swarm intelligence algorithm, and its performance in ...