Zhikui Huo,Guoliang Liu,Jiannan Li
Zhikui Huo
Background: The incidence of colorectal cancer (CRC) is increasing worldwide, particularly among younger adults. Consequently, developing novel treatment strategies for CRC is necessary. As a recently developed therapeuti...
The GOLM1-ACLY pathway regulates macrophage-secreted EFEMP1 via H3K27ac modifications to drive tumor progression [0.03%]
Lan Zhen,Min Min,Xinglin Mo et al.
Lan Zhen et al.
Background: Macrophages play crucial regulatory roles within the tumor immune microenvironment (TIME) and significantly influence tumor progression. GOLM1 has been identified as being closely associated with a variety of ...
Transglutaminase 2 modulates inflammatory angiogenesis via vascular endothelial growth factor receptor 2 pathway in inflammatory bowel disease [0.03%]
Gaoshi Zhou,Mudan Zhang,Shuhui Zheng et al.
Gaoshi Zhou et al.
Objectives: Immune-driven inflammatory angiogenesis is a crucial component in the pathogenesis of inflammatory bowel disease (IBD). Nevertheless, the underlying mechanisms are still poorly understood. This study aims to i...
Redistribution of super-enhancers promotes malignancy in human hepatocellular carcinoma [0.03%]
超级增强子的重新分布促进人类肝细胞癌恶性发展
Jiacheng Huang,Liang Xu,Ye Chen et al.
Jiacheng Huang et al.
Introduction: Super-enhancers (SEs) are defined as the regulatory region where intensive transcriptional cofactors bind. Dysregulation of SEs is related to multiple diseases, however, its role in hepatocellular carcinoma ...
Scutellarein attenuates cancer cachexia-induced muscle atrophy via targeted inhibition of the JAK/STAT pathway [0.03%]
胡椒甲素通过靶向抑制JAK/STAT信号通路改善癌缓症肌肉萎缩
Heeju Ahn,Heeju Kim,Yeyoung Yoon et al.
Heeju Ahn et al.
Introduction: Cancer cachexia is a multifaceted metabolic syndrome characterized by severe loss of skeletal muscle and adipose tissue, diminishing both quality of life and survival in cancer patients. Despite its prevalen...
Aging induces sarcopenia by disrupting the crosstalk between the skeletal muscle microenvironment and myofibers [0.03%]
衰老通过破坏骨骼肌微环境与肌纤维间的信号转导诱发肌肉减少症
Ning Wang,Aojie Zheng,Youzhen Yan et al.
Ning Wang et al.
Background: Sarcopenia is a degenerative muscular disease associated with aging, characterized by a reduction in muscle mass and strength. This disease poses a significant global health challenge, owing to its high preval...
Study of the sensitization mechanism of immunoassay based on DNA tetrahedron spatial mediation for detecting imidacloprid in vegetables [0.03%]
基于DNA四面体空间介导的免疫检测咪鲜胺机制的研究
Rongqi Zhai,Donghui Xu,Beibei Liu et al.
Rongqi Zhai et al.
Introduction: Enzyme-linked immunoassay (ELISA) is a widely adopted method for detecting pesticide residues such as imidacloprid because of its speed, low cost, and simplicity. However, antibody adsorption immobilization ...
Corrigendum to "Disturbance of bile acids profile aggravates the diarrhea induced by capecitabine through inhibiting the Wnt/β-catenin pathway" [J. Adv. Res. 72 (2025) 591-604] [0.03%]
“Capecitabine诱导的腹泻通过抑制Wnt/β-catenin信号通路使胆汁酸谱型紊乱恶化”一文中关于图4插图和致谢部分的勘误通知
Zhipeng Wang,Zhijun Liu,Lili Cui et al.
Zhipeng Wang et al.
Microchemistry of 2D MOFs and their derivatives: From synthesis and catalytic mechanisms to energy storage [0.03%]
二维MOF及其衍生物的微化学：从合成和催化机制到能量存储
Yifei Gao,Guangna Ji,Zhongze Fang
Yifei Gao
Background: Compared with 3D MOFs, 2D MOFs and their derivatives (2D MOMs) have higher specific surface area, excellent electrochemical properties and structural tunability, and have great potential for hydrogen and energ...
Antimicrobial peptides: An important link in the game theory between plants and pathogens [0.03%]
植物和病原物“博弈论”中的重要环节——抗微生物肽的作用机制研究
Yanke Jiang,Jianfeng Du,Muhammad Zunair Latif et al.
Yanke Jiang et al.
Background: Antimicrobial peptides (AMPs) are peptides produced by organisms during the evolutionary process to defend themselves against external biotic stresses. Broadly speaking, AMP is a generic term for peptides evol...