Unleashing antifungal power: Nanopriming with selenium boosts JA signaling, suppresses pathogen enzymes, and activates phytoalexins for enhanced Fusarium graminearum resistance in maize [0.03%]
Qinyong Dong,Tingjie Huang,Yaling Bi et al.
Qinyong Dong et al.
Introduction: Stalk rot caused by Fusarium graminearum (F. graminearum) poses a serious threat to maize production, further exacerbated by contamination with the mycotoxin deoxyninylenol (DON). Although selenium nanoparti...
Co-decorated Co9S8/MoS2 heterostructures anchored to ultrathin graphene nanosheets as trifunctional electrocatalysts for self-powered universal-pH overall water splitting [0.03%]
Ailing Feng,Xu Zhu,Shijiu Ding et al.
Ailing Feng et al.
The design of multifunctional catalysts demonstrating exceptional efficiency in complete water electrolysis reactions across various pH environments represents a critical advancement for large-scale generation of renewable hydrogen. This st...
Ion channels in macrophages: dynamic regulation in cardiovascular and cerebrovascular diseases and therapeutic potential [0.03%]
Xiangqin Tian,Yangyang Jia,Changye Sun et al.
Xiangqin Tian et al.
Background: Cardiovascular and cerebrovascular diseases (CCVDs) have surpassed cancer as a significant global health challenge. As essential responders of the immune system, macrophages play a critical role in maintaining...
Systematic profiling of human gut bacteria with cyclic di-AMP secretion to enhance anti-tumor immunity [0.03%]
Linggang Zheng,Jumin Huang,Haoran Ni et al.
Linggang Zheng et al.
Introduction: Gut microbiota-derived metabolites play pivotal roles in clinical tumor treatment and progression. Cyclic di-AMP serves as both a bacterial signaling molecule and an immune activator of the STING pathway. Ho...
Exogenous biostimulants: mechanisms and innovations for enhancing seed germination and resilience under abiotic stress [0.03%]
Xin Liang,Yaohua Zhai,Jun Li et al.
Xin Liang et al.
Background: Seed germination is a critical phase in the plant life cycle that is highly vulnerable to abiotic stresses such as drought, salinity, and extreme temperatures, posing a severe threat to global crop establishme...
Jingyi Wang,Long Li,Chaonan Li et al.
Jingyi Wang et al.
Introduction: Numerous studies have elucidated plants' drought response, yet how plant leaves perceive this stress remains unclear. Objectives: ...
Tissue-resolved molecular landscape reveals hepatic regulatory networks and metabolic mediators underlying feed efficiency in chickens [0.03%]
Wenxin Zhang,Fangren Lan,Yuejie Han et al.
Wenxin Zhang et al.
Introduction: Residual feed intake (RFI) is a key indicator of feed efficiency in poultry and is regulated by coordinated physiological processes across multiple tissues. Improving feed efficiency is essential for sustain...
Restoring cardiolipin homeostasis mitigates cerebral ischemia-reperfusion injury by suppressing ATG5-mediated neuronal autophagy-dependent ferroptosis [0.03%]
Weichen Dong,Wenxin Zhang,Li Huang et al.
Weichen Dong et al.
Introduction: Cardiolipins (CLs) are mitochondria-specific phospholipids critically involved in neurological disorders. However, their roles in cerebral ischemia/reperfusion (I/R) injury remains largely underexplored. ...
The stress responsive transcription factor ATF4: from molecular structure to disease mechanisms [0.03%]
Jian-Rong Yuan,Jie Tang,Rui Sheng
Jian-Rong Yuan
Background: Activating transcription factor 4 (ATF4), a member of the ATF/CREB family, regulates cell survival and death via governing the expression of genes involved in integrated stress response, endoplasmic reticulum ...
Evolutionary-based deep learning network model using adaptive mixing differential evolution and application in acute pulmonary embolism [0.03%]
Mingjing Wang,Hao ShangGuan,Yang Yang et al.
Mingjing Wang et al.
Introduction: Acute pulmonary embolism (APE) is characterized by high incidence and mortality, along with non-specific clinical manifestations. Its common symptoms such as dyspnea, chest pain, cough, and hemoptysis can al...