Valerenic acid attenuates pathological myocardial hypertrophy by promoting the utilization of multiple substrates in the mitochondrial energy metabolism [0.03%]
伐伦酸通过促进线粒体能量代谢中多种底物的利用来减轻病理性心肌肥大
Tiantian Liu,Xu Chen,Qianbin Sun et al.
Tiantian Liu et al.
Introduction: Valerenic acid (VA) is a unique and biologically active component in Valeriana officinalis L., which has been reported to have a regulatory effect on the cardiovascular system. However, its therapeutic effec...
Targeting lipid metabolism of macrophages: A new strategy for tumor therapy [0.03%]
针对巨噬细胞的脂质代谢：肿瘤治疗的新策略
Nan Shao,Hui Qiu,Jing Liu et al.
Nan Shao et al.
Background: Lipid metabolism has been implicated in a variety of normal cellular processes and strongly related to the development of multiple diseases, including tumor. Tumor-associated macrophage (TAM) has emerged as a ...
A narrative review about cognitive impairment in metabolic Dysfunction-Associated liver disease (MASLD): Another matter to face through a holistic approach [0.03%]
代谢功能障碍相关性肝病(MASLD)中的认知障碍的叙述综述:通过整体方法面对的另一个问题
Marica Meroni,Miriam Longo,Erika Paolini et al.
Marica Meroni et al.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic hepatic disorder worldwide in both adults and children. It is well established that MASLD represents the hepatic mani...
Claudia Fornelli,Alessia Sofia Cento,Lorenzo Nevi et al.
Claudia Fornelli et al.
Introduction: Obesity, one of the most frequent health problems in the adult population, is a condition characterized by excessive white adipose tissue accumulation and accompanied by the increased risk to develop other d...
Recent advances in integrated solar cell/supercapacitor devices: Fabrication, strategy and perspectives [0.03%]
太阳能电池/超级电容器集成装置的最新进展：制造、策略与展望
Qiaoling Zhang,Guodong Li,Fen Qiao
Qiaoling Zhang
Background: Solar cell/supercapacitor integrated devices (SCSD) have made some progress in terms of device structure and electrode materials, but there are still many key challenges in controlling electrode performance an...
Single-cell transcriptomic profiling of heart reveals ANGPTL4 linking fibroblasts and angiogenesis in heart failure with preserved ejection fraction [0.03%]
心脏单细胞转录谱分析揭示ANGPTL4与射血分数保留的心力衰竭中成纤维细胞和血管生成的关联
Guoxing Li,Huilin Zhao,Zhe Cheng et al.
Guoxing Li et al.
Introduction: Despite the high morbidity and mortality, the effective therapies for heart failure with preserved fraction (HFpEF) are limited as the poor understand of its pathophysiological basis. ...
DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD [0.03%]
DNA低甲基化介导的GADD45B过表达促进气道炎症和COPD中的上皮细胞衰老
Yuan Zhan,Qian Huang,Zhesong Deng et al.
Yuan Zhan et al.
Introduction: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease typically characterized by chronic airway inflammation, with emerging evidence highlighting the driving role of cellular senescence-rel...
Therapeutic application and potential mechanism of plant-derived extracellular vesicles in inflammatory bowel disease [0.03%]
植物源细胞外囊泡在炎症性肠病中的治疗应用及潜在机制
Jinling Li,Ting Luo,Dou Wang et al.
Jinling Li et al.
Background: Plant-derived extracellular vesicles (PDEVs) are membrane vesicles characterized by a phospholipid bilayer as the basic skeleton that is wrapped by various functional components of proteins and nucleic acids. ...
New molecular mechanisms to explain the neuroprotective effects of insulin-like growth factor II in a cellular model of Parkinson's disease [0.03%]
胰岛素样生长因子II对帕金森氏病细胞模型的神经保护效应的新分子机制解释
Silvana-Yanina Romero-Zerbo,Nadia Valverde,Silvia Claros et al.
Silvana-Yanina Romero-Zerbo et al.
Introduction: One of the hallmarks of Parkinsońs Disease (PD) is oxidative distress, leading to mitochondrial dysfunction and neurodegeneration. Insulin-like growth factor II (IGF-II) has been proven to have antioxidant ...
High SERS performance of functionalized carbon dots in the detection of dye contaminants [0.03%]
功能化碳点在染料污染物检测中的高性能SERS效应
Yanqiu Yang,Lingru Kong,Yong Ding et al.
Yanqiu Yang et al.
Introduction: The long-term overuse of malachite green (MG) has potential carcinogenic, teratogenic, and mutagenic effects. The functional nanocomposite is novel and challenging to construct and implement through surface ...