Duo-role Platelet-rich Plasma: temperature-induced fibrin gel and growth factors' reservoir for microneedles to promote hair regrowth [0.03%]
双重作用富血小板血浆：温度诱导的纤维蛋白凝胶和用于微针递送促进毛发再生的生长因子储存库
Yang Sun,Lunan Yang,Lijuan Du et al.
Yang Sun et al.
Introduction: Alopecia concerns more than half our adult population. Platelet-rich plasma (PRP) has been applied in skin rejuvenation and hair loss treatment. However, the pain and bleeding during injection and the troubl...
FUNDC1 interacts with GPx4 to govern hepatic ferroptosis and fibrotic injury through a mitophagy-dependent manner [0.03%]
FUNDC1通过线粒体自噬依赖的方式与GPx4相互作用以调控肝细胞铁死亡及纤维化损伤
Yaguang Bi,Shuolin Liu,Xing Qin et al.
Yaguang Bi et al.
Introduction: Liver fibrosis is a life-threatening pathological anomaly which usually evolves into advanced liver cirrhosis and hepatocellular carcinoma although limited therapeutic option is readily available. FUN14 doma...
Anupam Dhasmana,Swati Dhasmana,Sudhir Kotnala et al.
Anupam Dhasmana et al.
Background: The trends of pancreatic cancer (PanCa) incidence and mortality are on rising pattern, and it will be a second leading cause of cancer related deaths by 2030. Pancreatic ductal adenocarcinoma (PDAC), major for...
CD11b mediates hypertensive cardiac remodeling by regulating macrophage infiltration and polarization [0.03%]
CD11b通过调节巨噬细胞浸润和极化介导高血压性心脏重塑
Yun-Long Zhang,Jie Bai,Wei-Jia Yu et al.
Yun-Long Zhang et al.
Introduction: Leukocyte infiltration is an early event during cardiac remodeling frequently leading to heart failure (HF). Integrins mediate leukocyte infiltration during inflammation. However, the importance of specific ...
Gut/rumen-mammary gland axis in mastitis: Gut/rumen microbiota-mediated "gastroenterogenic mastitis" [0.03%]
胃肠/瘤胃-乳腺轴在乳房炎中的作用：肠/瘤胃微生物群介导的“胃肠源性乳房炎”
Xiaoyu Hu,Zhaoqi He,Caijun Zhao et al.
Xiaoyu Hu et al.
Background: Mastitis is an inflammatory response in the mammary gland that results in huge economic losses in the breeding industry. The aetiology of mastitis is complex, and the pathogenesis has not been fully elucidated...
Phytochemicals and quaternary phosphonium ionic liquids: Connecting the dots to develop a new class of antimicrobial agents [0.03%]
植物化学成分和季𬭸盐离子液体：开发一类新型抗菌剂的新思路
Daniel Chavarria,Anabela Borges,Sofia Benfeito et al.
Daniel Chavarria et al.
Introduction: The infections by multidrug-resistant bacteria are a growing threat to human health, and the efficacy of the available antibiotics is gradually decreasing. As such, new antibiotic classes are urgently needed...
Oxidative stress induced by Etoposide anti-cancer chemotherapy drives the emergence of tumor-associated bacteria resistance to fluoroquinolones [0.03%]
依托泊苷抗肿瘤化疗诱发的氧化应激促进肿瘤相关细菌耐氟喹诺酮类抗生素产生
Shan Wang,Shepherd Yuen Chan,Yanlin Deng et al.
Shan Wang et al.
Introduction: Antibiotic-resistant bacterial infections, such as Pseudomonas aeruginosa and Staphylococcus aureus, are prevalent in lung cancer patients, resulting in poor clinical outcomes and high mortality. Etoposide (...
Bavachinin protects the liver in NAFLD by promoting regeneration via targeting PCNA [0.03%]
巴瓦チン通过靶向PCNA促进肝再生从而保护NAFLD小鼠肝脏
Xi Dong,Shan Lu,Yu Tian et al.
Xi Dong et al.
Introduction: Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease all over the world, and no drug is approved for the treatment of NAFLD. Bavachinin (BVC) is proven to possess liver-protecting effect...
Sulfide-modified nanoscale zero-valent iron as a novel therapeutic remedy for septic myocardial injury [0.03%]
硫修饰的纳米零价铁作为治疗Septic心肌损伤的新方法
Daquan Wang,Huadong Zhao,Chao Deng et al.
Daquan Wang et al.
Introduction: Myocardial injury is a serious complication in sepsis with high mortality. Zero-valent iron nanoparticles (nanoFe) displayed novel roles in cecal ligation and puncture (CLP)-induced septic mouse model. Nonet...
Extracellular vesicles derived from Porphyromonas gingivalis induce trigeminal nerve-mediated cognitive impairment [0.03%]
牙龈卟啉单胞菌衍生的细胞外囊泡通过三叉神经诱导认知障碍
Xiaoyang Ma,Yoon-Jung Shin,Jong-Wook Yoo et al.
Xiaoyang Ma et al.
Introduction: Porphyromonas gingivalis (PG)-infected periodontitis is in close connection with the development of Alzheimer's disease (AD). PG-derived extracellular vesicles (pEVs) contain inflammation-inducing virulence ...