SIRT1, a target of miR-708-3p, alleviates fluoride-induced neuronal damage via remodeling mitochondrial network dynamics [0.03%]
SIRT1通过重塑线粒体网络动力学缓解氟诱导的神经元损伤(miR-708-3p靶点)
Qian Zhao,Guo-Yu Zhou,Qiang Niu et al.
Qian Zhao et al.
Introduction: Neurological dysfunction induced by fluoride contamination is still one of major concern worldwide. Recently, neuroprotective roles of silent information regulator 1 (SIRT1) focusing on mitochondrial functio...
CORM‑2 reduces cisplatin accumulation in the mouse inner ear and protects against cisplatin-induced ototoxicity [0.03%]
CORM-2减少小鼠内耳顺铂累积并保护其免受顺铂引起的耳毒性影响
Ah-Ra Lyu,Soo Jeong Kim,Min Jung Park et al.
Ah-Ra Lyu et al.
Introduction: Cisplatin is a life-saving anticancer compound used to treat multiple solid malignant tumors, while it causes permanent hearing loss. There is no known cure, and the FDA has not approved any preventative tre...
Ten metabolites-based algorithm predicts the future development of type 2 diabetes in Chinese [0.03%]
基于10种代谢产物的算法预测中国人群2型糖尿病的发生风险
Xiuli Su,Chloe Y Y Cheung,Junda Zhong et al.
Xiuli Su et al.
Introduction: Type 2 diabetes (T2D) is a heterogeneous metabolic disease with large variations in the relative contributions of insulin resistance and β-cell dysfunction across different glucose tolerance subgroups and e...
Laser additive manufacturing of shape memory biopolymer bone scaffold: 3D conductive network construction and electrically driven mechanism [0.03%]
激光增材制造形状记忆生物聚合物骨支架:三维导电网络构建及电驱动机制研究
Cijun Shuai,Zhicheng Wang,Feng Yang et al.
Cijun Shuai et al.
Introduction: The electro-actuated shape memory polymer scaffold has gained increasing attentions on the utilization of minimally invasive surgery for bone defect repair, which requires to construct an efficient conductiv...
Effects of microbial agent and microbial fertilizer input on soil microbial community structure and diversity in a peanut continuous cropping system [0.03%]
微生物菌剂和微生物肥料施用对连作花生田土壤微生物群落结构及多样性的影响
Taswar Ahsan,Pei-Cong Tian,Jie Gao et al.
Taswar Ahsan et al.
Introduction: The soil harbors a diverse array of microorganisms, and these are essential components of terrestrial ecosystems. The presence of microorganisms in the soil, particularly in the rhizosphere, is closely linke...
Exploring the roles and molecular mechanisms of RNA binding proteins in the sorting of noncoding RNAs into exosomes during tumor progression [0.03%]
探究RNA结合蛋白在肿瘤进展期间非编码RNA分类进入外泌体中的作用及分子机制
Ting Wang,Hui Zhang
Ting Wang
Background: RNA binding proteins (RBPs) play a role in sorting non-coding RNAs (ncRNAs) into exosomes. These ncRNAs, carried by exosomes, are involved in regulating various aspects of tumor progression, including metastas...
Shiyu Li,Shuangli Zhu,Jun Yu
Shiyu Li
Background: The microbiota inhabits the epithelial surfaces of hosts, which influences physiological functions from helping digest food and acquiring nutrition to regulate metabolism and shaping host immunity. With the de...
Zhihan Lyu,Mikael Fridenfalk
Zhihan Lyu
Introduction: The concept of the metaverse, a virtual world where users can interact with a computer-generated environment, has received significant attention recently. ...
Mitochondrial-derived peptides in cardiovascular disease: Novel insights and therapeutic opportunities [0.03%]
线粒体衍生肽与心血管疾病:新的认识和治疗机会
Yang Li,Zhuozhuo Li,Yuanyuan Ren et al.
Yang Li et al.
Background: Mitochondria-derived peptides (MDPs) represent a recently discovered family of peptides encoded by short open reading frames (ORFs) found within mitochondrial genes. This group includes notable members includi...
Synergistic integration of digital twins and sustainable industrial internet of things for new generation energy investments [0.03%]
数字孪生和可持续工业物联网的协同集成在新一代能源投资中的应用
Gang Kou,Hasan Dinçer,Serhat Yüksel et al.
Gang Kou et al.
Introduction: This study aims to identify optimal digital twin policies for enhancing renewable energy projects. Through a comprehensive analysis, the research evaluates the potential of digital twins in the renewable ene...