Transcriptional and translational landscape fine-tune genome annotation and explores translation control in cotton [0.03%]
转录和翻译景观完善基因组注释并探索棉花翻译调控
Ghulam Qanmber,Qi You,Zhaoen Yang et al.
Ghulam Qanmber et al.
Introduction: The unavailability of intergenic region annotation in whole genome sequencing and pan-genomics hinders efforts to enhance crop improvement. ...
Modulating autophagy to treat diseases: A revisited review on in silico methods [0.03%]
从计算方法角度再谈自噬在疾病治疗中的调节作用
Lifeng Wu,Wenke Jin,Haiyang Yu et al.
Lifeng Wu et al.
Background: Autophagy refers to the conserved cellular catabolic process relevant to lysosome activity and plays a vital role in maintaining the dynamic equilibrium of intracellular matter by degrading harmful and abnorma...
PIBF1 regulates multiple gene expression via impeding long-range chromatin interaction to drive the malignant transformation of HPV16 integration epithelial cells [0.03%]
PIBF1通过阻碍长程染色体互作来调节多个基因表达以驱动HPV16整合上皮细胞恶性转化
Xiaomin Li,Ci Ren,Anni Huang et al.
Xiaomin Li et al.
Introduction: Human papillomavirus (HPV) integration can induce gene expression dysregulation by destroying higher-order chromatin structure in cervical cancer. ...
Infusion of GMSCs relieves autoimmune arthritis by suppressing the externalization of neutrophil extracellular traps via PGE2-PKA-ERK axis [0.03%]
GM-MSC输注通过PGE2-PKA-ERK轴抑制中性粒细胞胞外陷阱的释放从而缓解自身免疫性关节炎
Jun Zhao,Yan Liu,Xiaoyi Shi et al.
Jun Zhao et al.
Introduction: Rheumatoid arthritis (RA) is a systemic autoimmune disease with limited treatment success, characterized by chronic inflammation and progressive cartilage and bone destruction. Accumulating evidence has show...
Structural assessment of OsNIP2;1 highlighted critical residues defining solute specificity and functionality of NIP class aquaporins [0.03%]
OsNIP2;1的结构分析揭示了定义NIP亚家族水通道蛋白溶质特异性和功能的关键氨基酸残基
Yogesh Sharma,Vandana Thakral,Gaurav Raturi et al.
Yogesh Sharma et al.
Introduction: Nodulin-26-like intrinsic proteins (NIPs) are integral membrane proteins belonging to the aquaporin family, that facilitate the transport of neutral solutes across the bilayer. The OsNIP2;1 a member of NIP-I...
Tapan Kumar Mohanta,Yugal Kishore Mohanta,Prashant Kaushik et al.
Tapan Kumar Mohanta et al.
Background: Despite the exposure to arid environmental conditions across the globe ultimately hampering the sustainability of the living organism, few plant species are equipped with several unique genotypic, biochemical,...
Qi Wu,Zhou Liu,Bei Li et al.
Qi Wu et al.
Background: Cancer-associated cachexia is a multi-organ disorder associated with progressive weight loss due to a variable combination of anorexia, systemic inflammation and excessive energy wasting. Considering the impor...
Join the green team: Inducers of plant immunity in the plant disease sustainable control toolbox [0.03%]
加入绿色团队：可持续控制植物疾病的植物免疫诱导剂toolbox
Feng Zhu,Meng-Yao Cao,Qi-Ping Zhang et al.
Feng Zhu et al.
Background: Crops are constantly attacked by various pathogens. These pathogenic microorganisms, such as fungi, oomycetes, bacteria, viruses, and nematodes, threaten global food security by causing detrimental crop diseas...
Two mutations at KRT74 and EDAR synergistically drive the fine-wool production in Chinese sheep [0.03%]
中国羊粗毛生产的KRT74和EDAR两个突变的协同驱动作用
Benmeng Liang,Tianyou Bai,Yuhetian Zhao et al.
Benmeng Liang et al.
Introduction: Fine-wool sheep are the most common breed used by the wool industry worldwide. Fine-wool sheep have over a three-fold higher follicle density and a 50% smaller fiber diameter than coarse-wool sheep. ...
Antimicrobial activities of lavandulylated flavonoids in Sophora flavences against methicillin-resistant Staphylococcus aureus via membrane disruption [0.03%]
通过破坏细胞膜途径研究染料木素衍生物抗耐甲氧西林金黄色葡萄球菌活性
Zebin Weng,Fei Zeng,Minxin Wang et al.
Zebin Weng et al.
Introduction: The continuous emergence and rapid spread of multidrug-resistant bacteria have accelerated the demand for the discovery of alternative antibiotics. Natural plants contain a variety of antibacterial component...