Retinoic acid enhances ovarian steroidogenesis by regulating granulosa cell proliferation and MESP2/STAR/CYP11A1 pathway [0.03%]
视黄酸通过调控颗粒细胞增殖及MESP2/STAR/CYP11A1通路促进卵巢类固醇生成
Shuang Cai,Meixia Chen,Bangxin Xue et al.
Shuang Cai et al.
Introduction: Ovarian steroidogenesis not only affects the embryonic development and pregnancy outcome, but also associates with many diseases in mammals and women. Exploring the nutrients and mechanisms influencing ovari...
Postantibiotic leukocyte enhancement-mediated reduction of intracellular bacteria by macrophages [0.03%]
抗生素治疗后白细胞增强介导的巨噬细胞对胞内细菌的清除作用
Yifan Wu,Xiaoxia Gong,Jianzhong Shen et al.
Yifan Wu et al.
Introduction: Potentiation of the bactericidal activities of leukocytes, including macrophages, upon antibacterial agent administration has been observed for several decades and is summarized as the postantibiotic leukocy...
Targeting Trop2 by Bruceine D suppresses breast cancer metastasis by blocking Trop2/β-catenin positive feedback loop [0.03%]
通过阻断Trop2/β-catenin正反馈环抑制乳腺癌转移的Bruceine D靶向Trop2作用机制研究
Wenjuan Tang,Yu Hu,Kaihui Tu et al.
Wenjuan Tang et al.
Introduction: Tumor-associated calcium signal transducer 2 (Trop2) has been used as a transport gate for cytotoxic agents into cells in antibody-drug conjugate designs because of its expression in a wide range of solid tu...
Gut microbiota: A magical multifunctional target regulated by medicine food homology species [0.03%]
肠道微生物群：由药食同种物种调控的神奇多功能靶点
Wei-Fang Zuo,Qiwen Pang,Lai-Ping Yao et al.
Wei-Fang Zuo et al.
Background: The relationship between gut microbiota and human health has gradually been recognized. Increasing studies show that the disorder of gut microbiota is related to the occurrence and development of many diseases...
Novel ray of hope for diabetic wound healing: Hydrogen sulfide and its releasing agents [0.03%]
糖尿病伤口愈合的新希望——硫化氢及其供体药物
Xinyi Shi,Haonan Li,Fengrui Guo et al.
Xinyi Shi et al.
Background: Diabetes mellitus (DM) is a long-term metabolic disease accompanied by difficulties in wound healing placing a severe financial and physical burden on patients. As one of the important signal transduction mole...
Genomic loci associated with leaf abscission contribute to machine picking and environmental adaptability in upland cotton (Gossypium hirsutum L.) [0.03%]
与叶片脱落相关的基因组位点有助于陆地棉机械采收和环境适应性研究
Hongge Li,Xiangru Wang,Ning Qin et al.
Hongge Li et al.
Introduction: Defoliation by applying defoliants before machine picking is an important agricultural practice that enhances harvesting efficiency and leads to increased raw cotton purity. However, the fundamental characte...
Insights into modifiable risk factors of erectile dysfunction, a wide-angled Mendelian Randomization study [0.03%]
一项关于阳痿的可改变危险因素的启示性研究——一种广泛的孟德尔随机化研究
Yang Xiong,Fuxun Zhang,Yangchang Zhang et al.
Yang Xiong et al.
Introduction: The causal association between modifiable risk factors and erectile dysfunction (ED) remains unclear, which hinders the early identification and intervention of patients with ED. The present study aimed to c...
Zearalenone-14-glucoside specifically promotes dysplasia of Gut-Associated Lymphoid Tissue: A natural product for constructing intestinal nodular lymphatic hyperplasia model [0.03%]
zearalenone-14-葡萄糖苷可特异地促进肠道相关淋巴组织的异形增生：一种可用于构建肠结节性淋巴滤泡增生模型的天然产物
Haonan Ruan,Yunyun Wang,Jing Zhang et al.
Haonan Ruan et al.
Introduction: Zearalenone-14-glucoside (Z14G) is a modified mycotoxin that widely contaminates food across the world. Our preliminary experiment showed that Z14G degrades to zearalenone (ZEN) in the intestine exerting tox...
J-shaped association between LDL cholesterol and cardiovascular events: A longitudinal primary prevention cohort of over 2.4 million people nationwide [0.03%]
LDL胆固醇与心血管事件的J形关联：全国范围内的纵向一级预防队列研究（超过240万人年）
Chan Soon Park,Han-Mo Yang,Kyungdo Han et al.
Chan Soon Park et al.
Introduction: Low-density lipoprotein (LDL) cholesterol-lowering treatment is beneficial for the secondary or primary prevention of high-risk atherosclerotic cardiovascular disease (ASCVD). However, the prognostic implica...
Genomics comparisons of three chromosome-level mudskipper genome assemblies reveal molecular clues for water-to-land evolution and adaptation [0.03%]
三个高质量组装的弹涂鱼基因组揭示了登陆进化的遗传机制
Chao Bian,Yu Huang,Ruihan Li et al.
Chao Bian et al.
Introduction: Mudskippers are a large group of amphibious fishes that have developed many morphological and physiological capacities to live on land. Genomics comparisons of chromosome-level genome assemblies of three rep...