Exploring melatonin's multifaceted role in female reproductive health: From follicular development to lactation and its therapeutic potential in obstetric syndromes [0.03%]
褪黑素在女性生殖健康中的多重作用:从卵泡发育到泌乳及其在妇科学综合征治疗中的潜力
Qihui Li,Tenghui Zheng,Jiaming Chen et al.
Qihui Li et al.
Background: Melatonin is mainly secreted by the pineal gland during darkness and regulates biological rhythms through its receptors in the suprachiasmatic nucleus of the hypothalamus. In addition, it also plays a role in ...
Study on PTFE superhydrophobic coating modified by IC@dMSNs and its enhanced antibacterial effect [0.03%]
IC@dMSNs改性PTFE超疏水涂层及其抗菌性能研究
Weixing Zhang,Juan Du,Fariha Kanwal et al.
Weixing Zhang et al.
Introduction: Vascular catheter-related infections and thrombosis are common and may lead to serious complications after catheterization. Reducing the incidence of such infections has become a significant challenge. ...
KRAS/PI3K axis driven GTF3C6 expression and promotes LUAD via FAK pathway [0.03%]
KRAS/PI3K轴驱动的GTF3C6表达通过FAK途径促进LUAD的发展
Xingzhao Ji,Mingqiang Liu,Tianyi Zhang et al.
Xingzhao Ji et al.
Introduction: Effective targeting drugs for KRAS mutation-mediated Lung Adenocarcinoma (LUAD) are currently are limited. Objectives: In...
Tolerogenic dendritic cell-mediated regulatory T cell differentiation by Chinese herbal formulation attenuates colitis progression [0.03%]
基于中药方剂诱导调节性T细胞分化抑制结肠炎的耐受型树突状细胞机制研究
Chunhua Huang,Cheng Lyu,Heung-Lam Mok et al.
Chunhua Huang et al.
Introduction: Ulcerative colitis (UC) is a chronic inflammatory disease characterized by loss of immune tolerance to luminal antigens and progressive intestinal tissue injury. Thus, the re-establishment of immune toleranc...
Abnormal changes in metabolites caused by m6A methylation modification: The leading factors that induce the formation of immunosuppressive tumor microenvironment and their promising potential for clinical application [0.03%]
m6A甲基化修饰引起的代谢物异常变化:诱导免疫抑制性肿瘤微环境形成的关键因素及其临床应用潜力展望
Liang Zhao,Junchen Guo,Shasha Xu et al.
Liang Zhao et al.
Background: N6-methyladenosine (m6A) RNA methylation modifications have been widely implicated in the metabolic reprogramming of various cell types within the tumor microenvironment (TME) and are essential for meeting the...
Application of atmospheric cold plasma for zearalenone detoxification in cereals: Kinetics, mechanisms, and cytotoxicity analysis [0.03%]
大气冷等离子体净化谷物中玉米赤霉烯酮的研究:动力学、机理及细胞毒性分析
Mengjie Liu,Junxia Feng,Yongqin Fan et al.
Mengjie Liu et al.
Introduction: Zearalenone (ZEN) is one of the most widely contaminated mycotoxins in world, posing a severe threat to human and animal health. Atmospheric cold plasma (ACP) holds great penitential in mycotoxin degradation...
Mitochondrial calcium uniporter as biomarker and therapeutic target for breast cancer: Prognostication, immune microenvironment, epigenetic regulation and precision medicine [0.03%]
线粒体钙单向转运蛋白作为乳腺癌生物标志物和治疗靶点的诊断、免疫微环境、表观遗传调控及精准医疗作用机制研究
Hung-Yu Lin,Pei-Yi Chu
Hung-Yu Lin
Introduction: Mitochondrial calcium uniporter (MCU) is a central subunit of MCU complex that regulate the levels of calcium ions within mitochondria. A comprehensive understanding the implications of MCU in clinical progn...
Nanozyme-based visual diagnosis and therapeutics for myocardial infarction: The application and strategy [0.03%]
基于纳米酶的心肌梗死可视化诊断与治疗:应用和策略
Yuan Zhang,Wanpeng Yu,Lei Zhang et al.
Yuan Zhang et al.
Background: Myocardial infarction (MI) is a heart injury caused by ischemia and low oxygen conditions. The occurrence of MI lead to the activation of a large number of neutrophils and macrophages, inducing severe inflamma...
Maximizing throughput in NOMA-enable industrial IoT networks using digital twin and reinforcement learning [0.03%]
基于数字孪生与强化学习的非正交多址工业物联网调度研究
Sekione Reward Jeremiah,David Camacho,Jong Hyuk Park
Sekione Reward Jeremiah
Introduction: Increased deployment of heterogeneous and complex Industrial Internet of Things (IIoT) applications such as predictive maintenance and asset tracking places a substantial strain on the limited computational ...
Pleiotropic role of GAS6 in cardioprotection against ischemia-reperfusion injury [0.03%]
GAS6在缺血再灌注损伤心脏保护作用中的多效性功能研究
Chenxi Lu,Yanbin Song,Xiaopeng Wu et al.
Chenxi Lu et al.
Introduction: Myocardial ischemia-reperfusion (IR) injury is a common medical issue contributing to the onset and progression of ischemic heart diseases (IHD). Growth arrest-specific gene 6 (GAS6), a vitamin K-dependent s...