A scalable microfluidic-blow-spinning platform for fabricating food-grade γ-cyclodextrin metal-organic-framework nanofiber composites with sustained release of thymol: a preservation case study of fresh-cut fruits [0.03%]
一种可扩展的微流控吹纺平台，用于制造食品级γ-环糊精金属有机骨架纳米纤维复合材料，并具有百里酚缓释性能：以切新鲜水果保鲜为例的研究
Zi-An Deng,Yibo Liu,Wenjing Shi et al.
Zi-An Deng et al.
Introduction: Developing advanced functional composites by integrating metal-organic frameworks (MOFs) with polymeric nanofibers are important research in materials science. This strategy of incorporating MOFs into polyme...
Host genetics and the gut microbiota jointly shape apparent fiber digestibility in pigs [0.03%]
宿主基因和肠道微生物组共同决定猪对纤维消化率的影响
Liming Xu,Taoran Du,Jin Zhou et al.
Liming Xu et al.
Introduction: Host genes regulate gut microbial composition, but the mechanisms by which they influence porcine fiber-degrading bacteria remain poorly understood. Additionally, the potential for integrating host genetics ...
Long noncoding RNA AC007637.1 inhibits tumorigenesis by regulating the Trim25/PCNA axis in colorectal cancer [0.03%]
长非编码RNA AC007637.1通过调节Trim25/PCNA轴抑制结直肠癌肿瘤发生
Xue Wang,Jiuming Li,Chu Hao et al.
Xue Wang et al.
Introduction: Mounting evidence indicates that long noncoding RNAs (lncRNAs) play crucial roles in tumorigenesis and progression. Objectives: ...
Multicenter deep learning for multi-abnormality screening on hip radiographs: development, external validation, and assisted reader study [0.03%]
多中心学习在髋关节影像的多种病变筛查中的应用：模型开发、外部验证及辅助阅片研究
Shenghao Xu,Chaohui Guo,Qibo Xu et al.
Shenghao Xu et al.
Introduction: Hip abnormalities are a major cause of pain and functional impairment, yet missed diagnoses remain common due to high clinical workloads and interobserver variability. Existing deep learning (DL) models pred...
From repair to disease: lymphatic contributions to regeneration, cancer and ageing [0.03%]
从修复到疾病：淋巴系统对再生、癌症和衰老的贡献
Yuheng Zhang,Qi Tian,Yang Yang et al.
Yuheng Zhang et al.
Background: The lymphatic vasculature maintains tissue fluid homeostasis, lipid transport, and immune surveillance. Beyond these classical roles, lymphatic vessels regulate tissue development and repair through lymphangio...
UBTF-HSP90A-MIF stress circuit drives lenvatinib resistance and immune exclusion in hepatocellular carcinoma [0.03%]
UBTF-HSP90A-MIF应激通路驱动肝细胞癌仑伐替尼耐药及免疫排斥反应
Shiping Chen,Biao Wang,Yanfei Wu et al.
Shiping Chen et al.
Introduction: The clinical benefit of combining lenvatinib with PD-1 blockade in HCC is frequently constrained by adaptive resistance and the development of an immune-cold tumor microenvironment. ...
AnnoNet-TCMs: An annotation network-driven discovery of novel active compounds and mechanisms in traditional Chinese medicine [0.03%]
基于标注网络的中药新活性化合物及机制发现
Xiangyu Yan,Zifan Guo,Fanxing Zhou et al.
Xiangyu Yan et al.
Introduction: Understanding the mechanistic basis of Traditional Chinese Medicines (TCMs) remains challenging due to its multi-component, multi-target nature and the lack of systematic interpretability in current analytic...
An enzyme-responsive electrospun polyester membrane for sustained delivery of polymerized 2-methoxyestradiol to treat peritendinous adhesion [0.03%]
一种酶响应性电纺聚酯膜用于递送聚合型2-甲氧基他莫昔芬治疗腱周粘连
Weijun Huang,Qing Yu,Wenhao Lu et al.
Weijun Huang et al.
Introduction: Tendon injuries are frequently accompanied by peritendinous adhesion, leading to restricted joint mobility and functional impairment, while effective preventive strategies remain limited in clinical practice...
Multi-cycle application of Virgibacillus dokdonensis induces a root-knot nematode-suppressive soil via specifically recruiting functional Pseudomonas [0.03%]
芽孢杆菌多江ensis菌株的多次接种诱导土壤招募功能假单胞菌降低根结线虫侵染
Wen Chen,Yuanpu Zhang,Yaru Tian et al.
Wen Chen et al.
Introduction: Inducing the development of disease-suppressive soils against root-knot nematodes (RKNs) represents a sustainable strategy for reducing pesticide dependence, with microbial management serving as a core appro...
Phenotypically and functionally unique CD86 expression CD8 T cell subset shapes immune regulation in the tumor microenvironment [0.03%]
肿瘤微环境中表型和功能独特的CD86表达的CD8 T细胞亚群塑造免疫调节作用
Xin Hu,Yifang Shui,Yixian Fan et al.
Xin Hu et al.
Introduction: The tumor microenvironment (TME) promotes immune evasion by fostering regulatory immune programs. Although CD8+ regulatory T cells have been described, their identity, upstream drivers and impact in tumors r...