Synthesis and anthelmintic activity of novel thiosemicarbazide and 1,2,4-triazole derivatives: In vitro, in vivo, and in silico study [0.03%]
新型噻二唑和1,2,4-三氮唑衍生物的合成及其驱虫活性:体外、体内及分子对接研究
Przemysław Kołodziej,Monika Wujec,Maria Doligalska et al.
Przemysław Kołodziej et al.
Introduction: Intestinal parasitic infections are neglected diseases and, due to the increasing resistance of parasites to available drugs, they pose an increasing therapeutic challenge. Therefore, there is a great need f...
Genome engineering on size reduction and complexity simplification: A review [0.03%]
大小减小和复杂度简化的基因组工程:综述
Xiang-Rong Chen,You-Zhi Cui,Bing-Zhi Li et al.
Xiang-Rong Chen et al.
Background: Genome simplification is an important topic in the field of life sciences that has attracted attention from its conception to the present day. It can help uncover the essential components of the genome and, in...
Bovine milk microbiota: Key players, origins, and potential contributions to early-life gut development [0.03%]
牛乳微生物群:关键参与者、起源及对生命早期肠道发育的潜在贡献
Wenli Guo,Shuai Liu,Muhammad Z Khan et al.
Wenli Guo et al.
Background: Bovine milk is a significant substitute for human breast milk and holds great importance in infant nutrition and health. Apart from essential nutrients, bovine milk also contains bioactive compounds, including...
Temporal trends of breast cancer burden in the Western Pacific Region from 1990 to 2044: Implications from the Global Burden of Disease Study 2019 [0.03%]
西太平洋地区1990年至2044年乳腺癌疾病负担的时空变化:全球疾病负担研究(GBD 2019)结果解读
Bing Wu,Ye Li,Baoguo Shi et al.
Bing Wu et al.
Introduction: Breast cancer (BC) is a malignant disease that occurs worldwide and poses serious health burden. Objectives: To assess th...
Dissecting the human gut microbiome to better decipher drug liability: A once-forgotten organ takes center stage [0.03%]
解析人类肠道微生物组以更好地解读药物的固有属性:一度被遗忘的人体器官成为研究重点
Jingwei Cai,Alexis Auster,Sungjoon Cho et al.
Jingwei Cai et al.
Background: The gut microbiome is a diverse system within the gastrointestinal tract composed of trillions of microorganisms (gut microbiota), along with their genomes. Accumulated evidence has revealed the significance o...
Multi-omic analysis of the extension of broccoli quality during storage by folic acid [0.03%]
叶酸延长 Broccoli 储藏期内品质的多组学分析研究
Yaqi Zhao,Junyan Shi,Bihong Feng et al.
Yaqi Zhao et al.
Introduction: Folic acid (FA) is a critical metabolite in all living organisms and an important nutritional component of broccoli. Few studies have been conducted on the impact of an exogenous application of FA on the pos...
Exogenous abscisic acid represses rice flowering via SAPK8-ABF1-Ehd1/Ehd2 pathway [0.03%]
外源脱落酸通过SAPK8-ABF1-Ehd1/Ehd2信号通路抑制水稻开花
Liqun Tang,Guanghao Li,Huimei Wang et al.
Liqun Tang et al.
Introduction: Rice flowering is a major agronomic trait, determining yield and ecological adaptability in particular regions. ABA plays an essential role in rice flowering, but the underlying molecular mechanism remains l...
Microbial diversity and functions in saline soils: A review from a biogeochemical perspective [0.03%]
盐土微生物多样性及功能:一种生物地球化学视角的综述
Guangliang Zhang,Junhong Bai,Yujia Zhai et al.
Guangliang Zhang et al.
Background: Soil salinization threatens food security and ecosystem health, and is one of the important drivers to the degradation of many ecosystems around the world. Soil microorganisms have extremely high diversity and...
Synergistic effect of cold gas plasma and experimental drug exposure exhibits skin cancer toxicity in vitro and in vivo [0.03%]
冷等离子体与实验药物的协同作用在体外和体内均显示出对皮肤癌的毒性效应
Lars Boeckmann,Julia Berner,Marcel Kordt et al.
Lars Boeckmann et al.
Introduction: Skin cancer is often fatal, which motivates new therapy avenues. Recent advances in cancer treatment are indicative of the importance of combination treatments in oncology. Previous studies have identified s...
Salicylic acid-doped iron nano-biostimulants potentiate defense responses and suppress Fusarium wilt in watermelon [0.03%]
水杨酸改性的铁纳米生物刺激素可增强瓜类作物的防御反应并抑制枯萎病病情发展
Muhammad Noman,Temoor Ahmed,Muhammad Shahid et al.
Muhammad Noman et al.
Introduction: Chemo- and bio-genic metallic nanoparticles (NPs), as a novel nano-enabled strategy, have demonstrated a great potential in crop health management. ...