Auricularia auricula polysaccharides attenuate obesity in mice through gut commensal Papillibacter cinnamivorans [0.03%]
银耳多糖通过肠道共栖菌Papilllibacter cinnamivorans抑制肥胖症状
Xin Zong,Hao Zhang,Luoyi Zhu et al.
Xin Zong et al.
Introduction: Auricularia auricula is a well-known traditional edible and medical fungus with high nutritional and pharmacological values, as well as metabolic and immunoregulatory properties. Nondigestible fermentable po...
The occurrence and management of fumonisin contamination across the food production and supply chains [0.03%]
食品生产和供应链中伏马菌素污染的发生和管控
Taotao Li,Jiajia Li,Jiasheng Wang et al.
Taotao Li et al.
Background: Fumonisins (FUMs) are among the most common mycotoxins in plant-derived food products. FUMs contamination has considerably impacted human and animal health, while causing significant economic losses. Hence, ma...
P53-response circRNA_0006420 aggravates lung cancer radiotherapy resistance by promoting formation of HUR/PTBP1 complex [0.03%]
circRNA_0006420通过促进HUR/PTBP1复合物的形成来加重由p53调控的肺癌放射耐药性
Zhao Ju,Mingjun Lei,Lihui Xuan et al.
Zhao Ju et al.
Background: p53 wild-type lung cancer cells can develop radiation resistance. Circular RNA (circRNA) consists of a family of transcripts with exclusive structures. circRNA is critical in tumorigenesis and is a potential b...
Resuscitation of viable but nonculturable bacteria promoted by ATP-mediated NAD+ synthesis [0.03%]
由ATP介导的NAD+合成促进休眠但有活性细菌复苏
Dong Yang,Wenxin Wang,Liang Zhao et al.
Dong Yang et al.
Introduction: Entry into the viable but nonculturable (VBNC) state is a survival strategy adopted by bacteria to survive harsh environment. Although VBNC cells still have metabolic activity, they lose the ability to form ...
Long-term exposure to PM2.5 and its components is associated with elevated blood pressure and hypertension prevalence: Evidence from rural adults [0.03%]
长期暴露于PM2.5及其组分与血压升高和高血压患病率增加有关:来自农村成年人的证据
Ruiyu Wu,Ning Kang,Caiyun Zhang et al.
Ruiyu Wu et al.
Introduction: The toxicity of fine particulate matter (PM2.5) is determined by its components, while the evidence regarding associations of PM2.5 components with blood pressure (BP) is limited, especially in rural areas. ...
Hsa_circ_0001402 alleviates vascular neointimal hyperplasia through a miR-183-5p-dependent regulation of vascular smooth muscle cell proliferation, migration, and autophagy [0.03%]
circRNA hsa_circ_0001402通过调控miR-183-5p依赖的血管平滑肌细胞增殖、迁移和自噬来缓解血管内膜增生
Jia-Jie Lin,Rui Chen,Li-Yun Yang et al.
Jia-Jie Lin et al.
Introduction: Vascular neointimal hyperplasia, a pathological process observed in cardiovascular diseases such as atherosclerosis and pulmonary hypertension, involves the abundant presence of vascular smooth muscle cells ...
Insecticide resistance reduces the profitability of insect-resistant rice cultivars [0.03%]
杀虫剂抗性降低了抗虫水稻品种的盈利能力
Rui Pang,Shihui Li,Weiwen Chen et al.
Rui Pang et al.
Introduction: Preventing crop yield loss caused by pests is critical for global agricultural production. Agricultural pest control has largely relied on chemical pesticides. The interaction between insecticide resistance ...
Ceramide-1-phosphate alleviates high-altitude pulmonary edema by stabilizing circadian ARNTL-mediated mitochondrial dynamics [0.03%]
脑苷肌醇通过稳定circadian ARNTL介导的线粒体动力学来缓解高原肺水肿
Liuyang Tian,Chenghui Zhao,Yan Yan et al.
Liuyang Tian et al.
Introduction: High-altitude pulmonary edema (HAPE) is a severe and potentially fatal condition with limited treatment options. Although ceramide kinase (CERK)-derived ceramide-1-phosphate (C1P) has been demonstrated to of...
Procyanidin C1 inhibits tumor growth and metastasis in colon cancer via modulating miR-501-3p/HIGD1A axis [0.03%]
Procyanidin C1通过调控miR-501-3p/HIGD1A轴抑制结肠癌的生长和转移
Jun-Lin Lv,Yu-Jun Tan,Yu-Shan Ren et al.
Jun-Lin Lv et al.
Introduction: Although colon (COAD) and rectal adenocarcinoma (READ) combined to refer to colorectal cancer (CRC), substantial clinical evidence urged that CRC should be treated as two different cancers due to compared wi...
Novel hydroxamic acid derivative induces apoptosis and constrains autophagy in leukemic cells [0.03%]
新型羟胺酸衍生物通过诱导凋亡和限制自噬抑制白血病细胞生长
Marten A Fischer,Al-Hassan M Mustafa,Kristin Hausmann et al.
Marten A Fischer et al.
Introduction: Posttranslational modification of proteins by reversible acetylation regulates key biological processes. Histone deacetylases (HDACs) catalyze protein deacetylation and are frequently dysregulated in tumors....