Fucoidan alleviates high sucrose-induced metabolic disorders and enhances intestinal homeostasis through modulation of Notch signaling [0.03%]
岩藻糖硫酸酯通过调节诺特定理信号缓解高果糖诱导的代谢紊乱和增强肠道稳态
Jian Liu,Weiqiang Xia,Qifang Wu et al.
Jian Liu et al.
Introduction: The therapeutic potential of fucoidan (FUC), a natural polysaccharide, in metabolic disorders is recognized, yet its underlying mechanisms remain unclear. ...
N-succinyl-chitosan as ecofriendly pesticide carriers: Nano encapsulation and synergistic antifungal effect on 4-hydroxyphenyl-2-propenyl-1-one derivatives based on chalcone structure [0.03%]
基于查尔酮结构的4-羟基苯基-2-丙烯基-1-酮衍生物的协同抗真菌作用及N-环状碳酸乙二酯壳聚糖作为环境友好型农药载体的研究
Zhi Xia,Qing Zhou,Yu Zhang et al.
Zhi Xia et al.
Introduction: Traditional pesticides have poor-water solubility, high toxicity and low bioavailability. Therefore, it is of great significance for the sustainable and healthy development of the pesticide industry to devel...
Unlocking the crucial role of cancer-associated fibroblasts in tumor metastasis: Mechanisms and therapeutic prospects [0.03%]
癌相关成纤维细胞在肿瘤转移中的关键作用：机制和治疗前景
Yingxue Liu,Xiaoyan Zhang,Wenchao Gu et al.
Yingxue Liu et al.
Background: Tumor metastasis represents a stepwise progression and stands as a principal determinant of unfavorable prognoses among cancer patients. Consequently, an in-depth exploration of its mechanisms holds paramount ...
Sympathetic hyperinnervation drives abdominal aortic aneurysm development by promoting vascular smooth muscle cell phenotypic switching [0.03%]
交感神经支配通过促进血管平滑肌细胞表型转换来驱动腹主动脉瘤的发展
Zhenquan Tang,Jingfang Xie,Ming Jin et al.
Zhenquan Tang et al.
Introduction: Sympathetic hyperinnervation plays an important role in modulating the vascular smooth muscle cell (VSMC) phenotype and vascular diseases, but its role in abdominal aortic aneurysm (AAA) is still unknown. ...
The biomedical application of inorganic metal nanoparticles in aging and aging-associated diseases [0.03%]
无机金属纳米颗粒在衰老及与衰老相关疾病中的生物医学应用
Yuqing Meng,Junzhe Zhang,Yanqing Liu et al.
Yuqing Meng et al.
Aging and aging-associated diseases (AAD), including neurodegenerative disease, cancer, cardiovascular diseases, and diabetes, are inevitable process. With the gradual improvement of life style, life expectancy is gradually extended. Howeve...
Cotton transposon-related variome reveals roles of transposon-related variations in modern cotton cultivation [0.03%]
棉花转座子相关变异组揭示了转座子衍生变异在栽培棉进化中的作用
Shang Liu,Hailiang Cheng,Youping Zhang et al.
Shang Liu et al.
Introduction: Transposon plays a vital role in cotton genome evolution, contributing to the expansion and divergence of genomes within the Gossypium genus. However, knowledge of transposon activity in modern cotton cultiv...
A comprehensive review and advanced biomolecule-based therapies for osteoporosis [0.03%]
骨质疏松的全面综述与先进生物分子治疗方案
Maqsood Ali,Yong-Sik Kim
Maqsood Ali
Background: The prevalence of osteoporosis (OP) on a global scale is significantly elevated that causes life threatening issues. The potential of groundbreaking biomolecular therapeutics in the field of OP is highly encou...
Silicon: A valuable soil element for improving plant growth and CO2 sequestration [0.03%]
硅：一种有益的土壤元素可改善植物生长和二氧化碳固定
Abdul Latif Khan
Abdul Latif Khan
Background: Silicon (Si), the second most abundant and quasi-essential soil element, is locked as a recalcitrant silicate mineral in the Earth's crust. The physical abundance of silicates can play an essential role in inc...
Engineering DMNT emission in cotton enhances direct and indirect defense against mirid bugs [0.03%]
工程化棉花中的DMNT排放可增强对蚜虫的直接和间接防御能力
Dong Teng,Danfeng Liu,Adel Khashaveh et al.
Dong Teng et al.
Introduction: As an important herbivore-induced plant volatile, (3E)-4,8-dimethyl-1,3,7-nonatriene (DMNT) is known for its defensive role against multiple insect pests, including attracting natural enemies. A terpene synt...
SLC7A11 as a therapeutic target to attenuate phthalates-driven testosterone level decline in mice [0.03%]
SLC7A11作为治疗靶点缓解邻苯二甲酸盐诱导的小鼠睾酮水平下降效应
Yi Zhao,Xue-Qi Wang,Rui-Qi Liu et al.
Yi Zhao et al.
Introduction: Phthalates exposure is a major public health concern due to the accumulation in the environment and associated with levels of testosterone reduction, leading to adverse pregnancy outcomes. However, the relat...