Identification and application of a candidate gene AhAftr1 for aflatoxin production resistance in peanut seed (Arachis hypogaea L.) [0.03%]
一种抗黄曲霉素基因AhAftr1在花生中的鉴定及应用研究
Bolun Yu,Nian Liu,Li Huang et al.
Bolun Yu et al.
Introduction: Peanut is susceptible to infection of Aspergillus fungi and conducive to aflatoxin contamination, hence developing aflatoxin-resistant variety is highly meaningful. Identifying functional genes or loci confe...
Molecular mechanisms controlling grain size and weight and their biotechnological breeding applications in maize and other cereal crops [0.03%]
控制谷粒大小和重量的分子机制及其在玉米等谷物作物生物技术育种中的应用
Yan Long,Cheng Wang,Chang Liu et al.
Yan Long et al.
Background: Cereal crops are a primary energy source for humans. Grain size and weight affect both evolutionary fitness and grain yield of cereals. Although studies on gene mining and molecular mechanisms controlling grai...
An ancient whole-genome duplication in barnacles contributes to their diversification and intertidal sessile life adaptation [0.03%]
甲壳亚门藤壶全基因组加倍事件及物种多样性与附着生活的演化适应性研究
Jianbo Yuan,Xiaojun Zhang,Xiaoxi Zhang et al.
Jianbo Yuan et al.
Introduction: Whole-genome duplication (WGD) is one of the most sudden and dramatic events rarely reported in invertebrates, but its occurrence can lead to physiological, morphological, and behavioral diversification. WGD...
CDK2-activated TRIM32 phosphorylation and nuclear translocation promotes radioresistance in triple-negative breast cancer [0.03%]
CDK2活化TRIM32磷酸化和核转位可促进三阴性乳腺癌的放射耐受性
Jianming Tang,Jing Li,Jiayan Lian et al.
Jianming Tang et al.
Introduction: Despite radiotherapy being one of the major treatments for triple-negative breast cancer (TNBC), new molecular targets for its treatment are still required due to radioresistance. CDK2 plays a critical role ...
A geminivirus crosses the monocot-dicot boundary and acts as a viral vector for gene silencing and genome editing [0.03%]
一种双生病毒跨越单子叶和双子叶的界限并作为基因沉默和基因组编辑的病毒载体
Jitendra Kumar,Anshu Alok,Brian J Steffenson et al.
Jitendra Kumar et al.
Introduction: Members of the family Geminiviridae have been reported to infect either a monocot plant or a dicot plant, but not both. This study reports a geminivirus, Wheat Dwarf India Virus (WDIV), first identified in w...
Deciphering mechanisms of cardiomyocytes and non-cardiomyocyte transformation in myocardial remodeling of permanent atrial fibrillation [0.03%]
持续性房颤心律重塑中心肌细胞和非肌形成机制的解析
Yixuan Sheng,Yin-Ying Wang,Yuan Chang et al.
Yixuan Sheng et al.
Introduction: Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia, and it significantly increases the risk of cardiovascular complications and morbidity, even with appropriate treatment. Tissue remodeling ha...
Enteric fungi protect against intestinal ischemia-reperfusion injury via inhibiting the SAA1-GSDMD pathway [0.03%]
肠真菌通过抑制SAA1-GSDMD途径防御肠道缺血再灌注损伤
Yihui Chen,Ben Han,Xu Guan et al.
Yihui Chen et al.
Introduction: Prophylactic antifungal therapy has been widely used for critical patients, but it has failed to improve patient prognosis and has become a hot topic. This may be related to disruption of fungal homeostasis,...
Calcium influx: An essential process by which α-Synuclein regulates morphology of erythrocytes [0.03%]
钙离子内流：通过该过程，α-突触核蛋白调控红细胞形态变化
Ying Yang,Min Shi,Xiaodan Liu et al.
Ying Yang et al.
Introduction: Morphological abnormalities of erythrocytes/red blood cells (RBCs), e.g., increased acanthocytes, in Parkinson's disease (PD) have been reported previously, although the underlying mechanisms remain to be ch...
Evolocumab prevents atrial fibrillation in rheumatoid arthritis rats through restraint of PCSK9 induced atrial remodeling [0.03%]
依折麦布通过抑制PCSK9诱导的心房重构预防类风湿性关节炎大鼠心房颤动发生
Xuejie Han,Yunlong Gao,Meijiao He et al.
Xuejie Han et al.
Introduction: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is implicated in the pathogenesis and progression of autoimmune disease. Patients with rheumatoid arthritis (RA) are at high risk of developing atrial fi...
AI-2 quorum sensing controlled delivery of cytolysin-A by tryptophan auxotrophic low-endotoxic Salmonella and its anticancer effects in CT26 mice with colon cancer [0.03%]
组氨酸营养缺陷的低内毒血症沙门菌通过AI-2群体感应控制释放细胞溶素A及其在CT26结肠癌小鼠中的抗肿瘤作用
Ram Prasad Aganja,Chandran Sivasankar,John Hwa Lee
Ram Prasad Aganja
Introduction: The limitations of conventional cancer therapies necessitate target-oriented, highly invasive, and safe treatment approaches. Hence, the intrinsic anti-tumor activity of Salmonella can offer better options t...