tsRNA modifications: An emerging layer of biological regulation in disease [0.03%]
疾病中的tsRNA修饰：新兴的生物学调控层
Yaomin Liang,Ding Ji,Xiaoling Ying et al.
Yaomin Liang et al.
Background: Transfer RNA (tRNA)-derived small RNA (tsRNA) represents an important and increasingly valued type of small non-coding RNA (sncRNA). The investigation of tRNA and tsRNA modification crosswalks has not only pro...
Rationally designed BCR-ABL kinase inhibitors for improved leukemia treatment via covalent and pro-/dual-drug targeting strategies [0.03%]
基于理性的BCR-ABL激酶抑制剂设计用于改善白血病治疗的共价和前药/双药策略
Jie Sun,Liang Lou,Chengjun Zhu et al.
Jie Sun et al.
Background: Chronic Myeloid Leukemia (CML) is a blood cancer that remains challenging to cure due to drug resistance and side effects from current BCR-ABL inhibitors. There is an urgent need for novel and more effective B...
Fabrication of nanogels to improve the toxicity and persistence of cycloxaprid against Diaphorina citri, the vector of citrus huanglongbing [0.03%]
制备纳稠胶以提高新烟碱类杀虫剂环丙虫酯对柑橘木虱的毒力和持效性
Li Cui,Guiyun Deng,Jianghong Wu et al.
Li Cui et al.
Introduction: Diaphorina citri is the most serious pest of citrus worldwide because it is the natural insect vector of huanglongbing. Cycloxaprid (Cyc) was highly toxic to D. citri. However, the poor solubility and stabil...
Metabolic phenotyping combined with transcriptomics metadata fortifies the diagnosis of early-stage Hepatocellular carcinoma [0.03%]
结合代谢表型和转录组元数据强化对早期肝细胞癌的诊断
Sun Jo Kim,Cheol Woon Jung,Nguyen Hoang Anh et al.
Sun Jo Kim et al.
Introduction: The low sensitivity of alpha-fetoprotein (AFP) renders it unsuitable as a stand-alone marker for early hepatocellular carcinoma (eHCC) surveillance. Therefore, additional blood-based biomarkers with enhanced...
Brain organoid maturation and implantation integration based on electrical signals input [0.03%]
基于电信号输入的类脑器官成熟和移植后整合研究
Xiao-Hong Li,Nan Hu,Zhe-Han Chang et al.
Xiao-Hong Li et al.
Introduction: Brain organoids are believed to be able to regenerate impaired neural circuits and reinstate brain functionality. The neuronal activity of organoids is considered a crucial factor for restoring host function...
Serum taurine affects lung cancer progression by regulating tumor immune escape mediated by the immune microenvironment [0.03%]
血清牛磺酸通过调节免疫微环境介导的肿瘤免疫逃逸影响肺癌进展
Tu-Liang Liang,Hu-Dan Pan,Pei-Yu Yan et al.
Tu-Liang Liang et al.
Introduction: Taurine is a naturally occurring sulfonic acid involved in various physiological and pathological processes, such as the regulation of calcium signaling, immune function, inflammatory response, and cellular ...
GmBSK1-GmGSK1-GmBES1.5 regulatory module controls heat tolerance in soybean [0.03%]
GmBSK1-GmGSK1-GmBES1.5调控模块控制大豆耐热性
Ze-Hao Hou,Yuan Gao,Jia-Cheng Zheng et al.
Ze-Hao Hou et al.
Introduction: Heat stress poses a severe threat to the growth and production of soybean (Glycine max). Brassinosteroids (BRs) actively participate in plant responses to abiotic stresses, however, the role of BR signaling ...
A wearable conductive hydrogel with triple network reinforcement inspired by bio-fibrous scaffolds for real-time quantitatively sensing compression force exerted on fruit surface [0.03%]
受生物纤维修支架启发的具有三级网络增强功能的可穿戴导电水凝胶用于实时定量感应水果表面承受的压力传感器
Zhichao Yang,Ziqiang Qin,Menglu Wu et al.
Zhichao Yang et al.
Introduction: Mechanical stresses incurred during post-harvest fruit storage and transportation profoundly impact decay and losses. Currently, the monitoring of mechanical forces is primarily focused on vibrational forces...
Chlorophyllase (PsCLH1) and light-harvesting chlorophyll a/b binding protein 1 (PsLhcb1) and PsLhcb5 maintain petal greenness in Paeonia suffruticosa 'Lv Mu Yin Yu' [0.03%]
芍药‘绿幕荫玉’花瓣绿色维持的叶绿素酶（PsCLH1）和天蓝素1（PsLhcb1）及PsLhcb5基因表达模式及功能研究
Qing Hao,Tongtong Li,Gaojie Lu et al.
Qing Hao et al.
Introduction: Green flowers are not an adaptive trait in natural plants due to the challenge for pollinators to discriminate from leaves, but they are valuable in horticulture. The molecular mechanisms of green petals rem...
Formononetin derivatives containing benzyl piperidine: A brand new, highly efficient inhibitor targeting Xanthomonas spp [0.03%]
含苄基派普氨的.formononetin衍生物：一种针对(Xanthomonas).物种的新一代高效抑制剂
Miaohe Zhang,Shuang Feng,Junrong Song et al.
Miaohe Zhang et al.
Introduction: Plant bacterial diseases take an incalculable toll on global food security. The indiscriminate use of chemical synthetic pesticide not only facilitates pathogen resistance of pathogenic bacteria, but also po...