Alisol B 23-acetate broadly inhibits coronavirus through blocking virus entry and suppresses proinflammatory T cells responses for the treatment of COVID-19 [0.03%]
alisol B 23- acetate通过抑制病毒进入和抑制促炎症T细胞反应广谱对抗冠状病毒可治疗新冠肺炎
Qiaohui Du,Ronghui Liang,Meiling Wu et al.
Qiaohui Du et al.
Introduction: Emerging severe acute respiratory syndrome (SARS) coronavirus (CoV)-2 causes a global health disaster and pandemic. Seeking effective anti-pan-CoVs drugs benefit critical illness patients of coronavirus dise...
Set1/COMPASS regulates growth, pathogenicity, and patulin biosynthesis of Penicillium expansum via H3K4 methylation and the interaction with PeVelB [0.03%]
Set1/COMPASS通过H3K4甲基化和与PeVelB的互作调控盘状青霉菌生长、致病性和.patulin生物合成
Xiaodi Xu,Yong Chen,Zhanquan Zhang et al.
Xiaodi Xu et al.
Introduction: Penicillium expansum is a harmful plant fungal pathogen that causes blue mold disease and produces mycotoxin patulin, leading to huge economic losses and food safety hazard. Set1 associated complex Set1/COMP...
Immune response and mesenchymal transition of papillary thyroid carcinoma reflected in ultrasonography features assessed by radiologists and deep learning [0.03%]
放射科医师和深度学习评估的超声图像特征体现乳头状甲状腺癌的免疫反应及间质转化
Jandee Lee,Jung Hyun Yoon,Eunjung Lee et al.
Jandee Lee et al.
Introduction: Ultrasonography (US) features of papillary thyroid cancers (PTCs) are used to select nodules for biopsy due to their association with tumor behavior. However, the molecular biological mechanisms that lead to...
How do Food and drugs interact with gut microbiota? Toward better or worse health outcomes [0.03%]
食物和药物如何与肠道微生物群相互作用？更好的健康结果还是更差的健康结果？
Mohamed A Farag,Martin von Bergen,Ping Shao et al.
Mohamed A Farag et al.
IFP35 aggravates Staphylococcus aureus infection by promoting Nrf2-regulated ferroptosis [0.03%]
IFP35通过促进Nrf2调节的铁死亡加重金黄色葡萄球菌感染
Min Dai,Wei Ouyang,Yangle Yu et al.
Min Dai et al.
Introduction: Serious Staphylococcus aureus (SA) infection is one of the most life-threatening diseases. Interferon-induced protein 35 (IFP35) is a pleiotropic factor that participates in multiple biological functions, ho...
Blockchain and PUF-based secure key establishment protocol for cross-domain digital twins in industrial Internet of Things architecture [0.03%]
基于区块链和PUF的跨域数字孪生安全密钥建立协议用于工业物联网架构中
Khalid Mahmood,Salman Shamshad,Muhammad Asad Saleem et al.
Khalid Mahmood et al.
Introduction: The Industrial Internet of Things (IIoT) is a technology that connects devices to collect data and conduct in-depth analysis to provide value-added services to industries. The integration of the physical and...
Efficient improvement of the proliferation, differentiation, and anti-arthritic capacity of mesenchymal stem cells by simply culturing on the immobilized FGF2 derived peptide, 44-ERGVVSIKGV-53 [0.03%]
高效诱导间充质干细胞增殖、分化及抗关节炎能力的新方法：简单培养于FGF2衍生肽44-ERGVVSIKGV-53的固定表面即可实现
Soo Bin Lee,Ahmed Abdal Dayem,Sebastian Kmiecik et al.
Soo Bin Lee et al.
Introduction: The stem cell microenvironment has been evidenced to robustly affect its biological functions and clinical grade. Natural or synthetic growth factors, especially, are essential for modulating stem cell proli...
Piezo1 activation accelerates osteoarthritis progression and the targeted therapy effect of artemisinin [0.03%]
活化Piezo1加速骨关节炎进展及青蒿素靶向治疗效应研究
Donghao Gan,Chu Tao,Xiaowan Jin et al.
Donghao Gan et al.
Introduction: Osteoarthritis (OA) is a devastating whole-joint disease affecting a large population worldwide with no cure; its mechanism remains poorly defined. Abnormal mechanical stress is the main pathological factor ...
Nanomedicine-induced programmed cell death enhances tumor immunotherapy [0.03%]
纳米医学诱导的程序性细胞死亡可增强肿瘤免疫治疗
Jiaye Lu,Zongguang Tai,Junchao Wu et al.
Jiaye Lu et al.
Background: There has been widespread concern about the high cancer mortality rate and the shortcomings of conventional cancer treatments. Immunotherapy is a novel oncology therapy with high efficiency and low side effect...
Multiomics analysis reveals the molecular basis for increased body weight in silkworms (Bombyx mori) exposed to environmental concentrations of polystyrene micro- and nanoplastics [0.03%]
多组学分析揭示了环境浓度的微纳米塑料暴露对家蚕(Bombyx mori)体重增加的分子机制
Abrar Muhammad,Nan Zhang,Jintao He et al.
Abrar Muhammad et al.
Introduction: Micro- and nanoplastics (MNPs) are emerging environmental pollutants that have raised serious concerns about their potential impact on ecosystem and organism health. Despite increasing efforts to investigate...