A multi-objective African vultures optimization algorithm with binary hierarchical structure and tree topology for big data optimization [0.03%]
一种用于大数据优化的多目标非洲兀鹫优化算法，带有二元分层结构和树形拓扑结构
Bo Liu,Yongquan Zhou,Yuanfei Wei et al.
Bo Liu et al.
Introduction: Big data optimization (Big-Opt) problems present unique challenges in effectively managing and optimizing the analytical properties inherent in large-scale datasets. The complexity and size of these problems...
Zhenfei Guo,Bing Guo,Jufan Zhang et al.
Zhenfei Guo et al.
Background: Since its development in the 1980 s, chemical vapor deposition (CVD) diamond has found wide application in addressing various engineering challenges, owing to its outstanding characteristics, including excepti...
The effects of primary cilia-mediated mechanical stimulation on nestin+-BMSCs during bone-tendon healing [0.03%]
初级纤毛介导的力学刺激对骨腱结合区巢氏干细胞的影响研究
Huabin Chen,Han Xiao,Bing Wu et al.
Huabin Chen et al.
Introduction: Mechanical stimulation has been proven to promote bone-tendon interface (BTI) healing, but the mechanism remains unclear. Objective: ...
A novel prognostic scoring system for AML patients undergoing allogeneic hematopoietic stem cell transplantation with real world validation [0.03%]
基于真实世界验证的allo-HSCT后AML患者预后评估新系统
Qing Ya Wang,Yi Fan Han,Yu Han Li et al.
Qing Ya Wang et al.
Objectives: This study aims to develop a robust predictive model for survival in AML patients undergoing allo-HSCT. Methods: It was per...
Expression reduction and a variant of a P450 gene mediate chlorpyrifos resistance in Tetranychus urticae Koch [0.03%]
拟除虫菊酯抗性基因CYP333的表达及蛋白结构变化分析
Dandan Xu,Haojie Liao,Chao He et al.
Dandan Xu et al.
Introduction: Understanding how insects and mites develop resistance to chlorpyrifos is crucial for effective field management. Although extensive research has demonstrated that T. urticae exhibits high resistance to chlo...
Developing Patient-Derived 3D-Bioprinting models of pancreatic cancer [0.03%]
基于患者的胰腺癌三维生物打印模型的开发研究论文标题翻译
Hang Sun,Yan Wang,Minghao Sun et al.
Hang Sun et al.
Introduction: Pancreatic cancer (PC) remains a challenging malignancy, and adjuvant chemotherapy is critical in improving patient survival post-surgery. However, the intrinsic heterogeneity of PC necessitates personalized...
20(S)-Ginsenoside Rh2 overcomes gemcitabine resistance in pancreatic cancer by inhibiting LAMC2-Modulated ABC transporters [0.03%]
20(S)原人参皂苷Rh2通过抑制LAMC2调控的ABC转运蛋白介导的耐药克服吉西他滨耐药性研究胰腺癌中的研究
Yulin Wu,Juan Zhang,Yuanyang Tian et al.
Yulin Wu et al.
Introduction: Gemcitabine (GEM) is the first-line drug for pancreatic ductal adenocarcinoma (PDAC), but drug resistance severely restricts its chemotherapeutic efficacy. Laminin subunit γ2 (LAMC2) plays a crucial role in...
Whole-body mass spectrometry imaging reveals the systemic metabolic disorder and catecholamines biosynthesis alteration on heart-gut axis in heart failure rat [0.03%]
基于心脏-肠轴的心力衰竭大鼠全身质谱成像及代谢研究
Zhengyu Fang,Qingce Zang,Jiemei Chen et al.
Zhengyu Fang et al.
Introduction: Heart failure (HF) is a systemic metabolic disorder disease, across multiorgan investigations advancing knowledge of progression and treatment of HF. Whole-body MSI provides spatiotemporal information of met...
Haploinsufficiency of intraflagellar transport protein 172 causes autism-like behavioral phenotypes in mice through BDNF [0.03%]
纤毛动力蛋白复合物基因ITPRIP和IFT172的单倍剂量不足可导致自闭症光谱障碍及相关行为异常小鼠模型
Nanxi Zheng,Shilin Luo,Xin Zhang et al.
Nanxi Zheng et al.
Introduction: Primary cilia are hair-like solitary organelles growing on most mammalian cells that play fundamental roles in embryonic patterning and organogenesis. Defective cilia often cause a suite of inherited disease...
Biomarkers differentiating regression from progression among untreated cervical intraepithelial neoplasia grade 2 lesions [0.03%]
未治疗的宫颈上皮内瘤变Ⅱ级病灶转归与进展的鉴别标志物研究
Xiang Li,Yan Chen,Jing Xiong et al.
Xiang Li et al.
Background: Cervical intraepithelial neoplasia grade 2 (CIN2) is one of the precursor stages before cervical lesions develop into cervical cancer. The spontaneous development of CIN2 is ambiguous. One part of CIN2 lesions...