Helicobacter pylori-derived outer membrane vesicles: Pathogenic roles, microbiota interactions, and biomedical applications [0.03%]
幽门螺杆菌来源的外膜囊泡：致病作用、微生物组相互作用和生物医学应用
Xi Chen,Zibo Lin,Nanxi Wang et al.
Xi Chen et al.
Background: Helicobacter pylori (Hp) is a gram-negative, microaerophilic bacterium that infects approximate 45% of the global population. It is a key contributor to chronic gastritis, peptic ulcers, and gastric cancer. Am...
Honey bee nutritranscriptomics reveals key insights towards precision nutrition [0.03%]
营养转录组学揭示了蜜蜂精准营养研究的重要信息
Alexander McMenamin,Vincent Ricigliano
Alexander McMenamin
Introduction: Honey bees are essential managed pollinators faced by nutritional deficiencies which contributes to worldwide colony losses. The integration of nutrition science with genomics offers a powerful approach to o...
Cross-regulatory mechanisms linking ferroptosis, epigenetics, and circadian rhythm to mitochondrial quality control in diabetic cardiomyopathy [0.03%]
铁死亡、表观遗传学和昼夜节律相互调节机制与糖尿病心肌病线粒体质量控制之间的联系
Xinxin Liu,Yingqi Ma,Xuefeng Wang et al.
Xinxin Liu et al.
Diabetic cardiomyopathy (DCM) is a distinct cardiac disorder that develops independently of coronary artery disease and hypertension. Mitochondrial dysfunction is widely recognized as a hallmark pathological feature of DCM. Effective mitoch...
Evaluating intensive blood pressure control versus usual care on cardiovascular disease in patients with diabetes using win statistics: a subgroup analysis of a cluster randomized trial [0.03%]
糖尿病患者中强化血压控制与常规治疗对心血管疾病的影响——一项分组随机试验的次级分析：利用优势数进行评价
Guozhe Sun,Ning Ye,Chang Wang et al.
Guozhe Sun et al.
Introduction: Elevated arterial pressure constitutes a significant controllable risk element associated with detrimental outcomes in cardiovascular health. In comparison to standard blood pressure (BP) control (target lev...
Kang-Hui Wang,Jia-Yue Liu,Li-Juan Ma et al.
Kang-Hui Wang et al.
Background: Plants of the Panax genus, such as P. ginseng, P. notoginseng, and P. quinquefolius, have been utilized for culinary and medicinal purposes for millennia. Their pharmacological effects are largely attributed t...
Metabolic interactions drive microbial community succession and functional expression of Nongxiangxing (Strong-flavor) daqu [0.03%]
代谢互作驱动浓香型酒曲大曲微生物群落演替及功能表达
Shiyuan Ma,Yong Li,Cong Chen et al.
Shiyuan Ma et al.
Introduction: Nongxiangxing daqu is a wheat-based fermentation starter used in the production of Baijiu (a traditional Chinese distilled spirit), whose fermentation process during storage directly affects its quality. How...
CircCDYL promotes glycolysis to drive the progression of nasopharyngeal carcinoma [0.03%]
Circular RNA CircCDYL通过促进糖酵解来驱动鼻咽癌进展
Yujie Yang,Yian Wang,Hongke Qu et al.
Yujie Yang et al.
Introduction: CircRNAs play critical roles in the onset and progression of nasopharyngeal carcinoma (NPC), although their underlying mechanisms remain incompletely understood. ...
Therapeutic strategy for exosome-based bone regeneration to osteoporosis: Challenges and potential solutions [0.03%]
基于外泌体的骨再生治疗策略在防治骨质疏松症中的挑战与潜在解决方案
Anoop Puthiyoth Dayanandan,Alvin Bacero Bello,Yoshie Arai et al.
Anoop Puthiyoth Dayanandan et al.
Background: Osteoporosis (OP) is a progressive bone disease marked by reduced bone mass and microarchitectural deterioration, thereby increasing fracture risk. Current therapies only partly restore bone quality and often ...
Analyzing and forecasting global cervical cancer burden based on WHO's elimination strategy: insights and projections from a 1990-2021 global burden of disease (GBD) study covering 204 countries and territories [0.03%]
基于世卫组织消除策略的全球宫颈癌疾病负担分析与预测：一项涵盖204个国家和地区1990-2021年全球疾病负担研究的见解和预测结果
Yedong Huang,Wenyu Lin,Xiaoyun Chen et al.
Yedong Huang et al.
Introduction: Cervical cancer remains a major global public health challenge. In 2018, the WHO launched a strategy to eliminate cervical cancer, emphasizing the need for precise epidemiological assessments. ...
Circular RNA-mediated regulation of key signaling pathways in cardiovascular diseases: a review [0.03%]
circRNA介导的心血管疾病关键信号通路的调控：综述
Qianhui You,Weiwei Zhang,Chinying Koo et al.
Qianhui You et al.
Cardiovascular diseases (CVDs) are globally prevalent pathologies driven by dysregulated signaling networks. Circular RNAs (circRNAs), a class of covalently closed non-coding RNAs produced by back-splicingmechanism, in which a downstream 5'...