BnaGRP3 mediates salt tolerance via Na+/K+ homeostasis and BnaPIPs interactions in Brassica napus [0.03%]
盐 tolerance通过Na+/K+ 家园斯和BnaPIPs相互作用在油菜中.mediatemediates鹽_tolerance通过Na+/K+ 家园斯和BnaPIPs相互作用在油菜中的介导物质BnaGRP3
Ouqi Li,Min Zou,Xianfei Hou et al.
Ouqi Li et al.
Introduction: Rapeseed (Brassica napus L.) is a major oilseed crop with considerable potential for improving saline-alkali soils, yet the molecular mechanisms underlying its salt tolerance remain unclear. ...
Spatial heterogeneity of viral communities across the gastrointestinal tracts of ruminants [0.03%]
反刍动物胃肠病毒群的空间异质性分布
Shizhe Zhang,Qiushuang Li,Yongyi Peng et al.
Shizhe Zhang et al.
Introduction: Viruses are abundant biological entities within the gastrointestinal tract (GIT) of ruminants. Current understanding is extensive for bacterial and archaeal communities, but limited for viral communities. ...
High-fat diet score reveals total and cardiovascular mortality and identifies protein biomarkers in large cohorts [0.03%]
高脂肪饮食评分可揭示大量人群中的总死亡率和心血管死亡率并识别蛋白质生物标志物
Xiaomin Li,Xiangju Kong,Shanpeng Liu et al.
Xiaomin Li et al.
Introduction: The high-fat diet (HFD) has complex health implications, shaped by the composition of macronutrients and food sources. However, existing dietary assessment tools lack the precision required for effective ris...
Corrigendum to "CDK4/6 inhibitor PD-0332991 suppresses hepatocarcinogenesis by inducing senescence of hepatic tumor-initiating cells" [J. Adv. Res. 73 (2025) 357-373] [0.03%]
“CDK4/6抑制剂PD-0332991通过诱导肝肿瘤起始细胞衰老来抑制肝癌发生”一文的勘误[J.Adv.Res.73(2025)357-373]
Miaomiao Chen,Wenjian Chen,Shiwen Sun et al.
Miaomiao Chen et al.
Genotype-driven variations in lncRNA expression underlie predisposition to high-grade serous ovarian cancer [0.03%]
基因型驱动的长链非编码RNA表达变化是高级别浆液性卵巢癌易感性的基础
Mingming Lu,Yanan Chu,Ziwei Zhu et al.
Mingming Lu et al.
Introduction: New effective early diagnosis strategies and therapeutic targets are desperately needed for high-grade serous ovarian cancer (HGSOC). Previous functional interpretation of HGSOC genome-wide association studi...
Gut microbiota dysbiosis transmits deoxynivalenol toxicity and triggers liver inflammation [0.03%]
肠道菌群失调可传递脱氧雪腐镰刀菌烯醇毒性并引发肝炎
Jing Jin,Fangfang Li,Yafan Hu et al.
Jing Jin et al.
Introduction: Deoxynivalenol (DON), a mycotoxin produced by Fusarium species, is known to compromise gut barrier integrity and induce systemic inflammation. ...
Guaianolide dimer KGA-1002 targets GRP94 and triggers unfolded protein response-associated degradation of SKP2/AKT axis as a novel antihepatoma agent [0.03%]
瓜内酯二聚体KGA-1002靶向GRP94并触发未折叠蛋白反应相关SKP2/AKT轴的降解作为新型抗肝癌制剂
Qi-Hao Li,Tian-Ze Li,Yong-Cui Wang et al.
Qi-Hao Li et al.
Introduction: Hepatocellular carcinoma (HCC) remains a highly lethal malignant tumor with limited treatment options. The guaianolide dimer KGA-1002 exhibited significant inhibitory effects on HCC cells, but the specific t...
MAC5A dual-functionally regulates cold responses at both transcriptional and post-transcriptional levels [0.03%]
MAC5A在转录和转录后水平上双重调控冷响应
Shuo Wang,Zhiyin Meng,Hua Liu et al.
Shuo Wang et al.
Introduction: Plant cold responses have been extensively studied at the transcriptional level, particularly focusingon conserved transcription factors (TFs) such as C-repeat binding factors (CBFs). However, the post-trans...
Injectable multi-component hydrogel as an inhibitor of choline kinase α achieved the treatment of malignant ascites by inhibiting PI3K/AKT/mTOR signaling pathway [0.03%]
可注射多组分水凝胶通过抑制CKα 成为治疗恶性腹水的PI3K / AKT / mTOR信号通路抑制剂
Yuqin Yang,Jinchai Qi,Zicheng Zhu et al.
Yuqin Yang et al.
Introduction: Primary liver cancer remains the third leading cause of global cancer-related mortality, with hepatocellular carcinoma (HCC) constituting the predominant histological subtype. The development of malignant as...
Illustrating the functional heterogeneity of M-MDSCs to predict sepsis outcomes [0.03%]
通过绘制M-MDSCs的功能异质性来预测脓毒症的预后
Guoxing Tang,Wenjin Xing,Lin Zhu et al.
Guoxing Tang et al.
Introduction: Sepsis remains one of the leading causes of death worldwide. Monocytes play a pivotal role in sepsis due to their dual role in both pro-inflammation and immunosuppression. However, the phenotypic markers and...