Plasma proteomics identifies S100A8/A9 as a novel biomarker and therapeutic target for fulminant myocarditis [0.03%]
血浆蛋白质组学鉴定出S100A8/A9是急进性心肌炎的新型生物标志物和治疗靶点
Wu He,Junfang Wu,Dongxue Wang et al.
Wu He et al.
Introduction: Fulminant myocarditis (FM) is a lethal inflammatory myocardial disease characterized by rapid progression and poor prognosis. Investigating plasma proteins linked to FM may elucidate underlying pathological ...
Design of a sustained-release nanosystem for ultra-efficient absorption of anthocyanins and regulating lung damage through the "lung-gut" axis [0.03%]
一种用于高效吸收花色苷的长效纳米系统设计及其通过“肺-肠”轴调节肺损伤的研究
Jin-Long Tian,Nuo Wang,Qin-Fu Zhao et al.
Jin-Long Tian et al.
Introduction: Anthocyanins have various health benefits but are limited by fast elimination and low bioavailability. Many studies have shown that nano delivery systems are effective in improving the intestinal absorption ...
Defect passivation and transformation of Ti3C2Tx MXene hollow microsphere for superior electrochemical performance and sodium-ions storage [0.03%]
Ti3C2Tx MXene空心微球的缺陷钝化及转化实现优异电化学性能和钠离子存储能力
Ningning Liu,Xiaochen Zhang,Jinfeng Chen et al.
Ningning Liu et al.
The commercialization of MXene-based electrodes for sodium ion capture in aqueous solutions is limited by poor stability, which is attributed to edge and surface defects. In this study, 3D Ti3C2Tx MXene hollow microsphere (MHM) is construct...
Single-nucleus RNA sequencing reveals Cntnap2+ astrocytes triggering a hypertensive effect in the rostral ventrolateral medulla by disrupting glutamate uptake [0.03%]
单核RNA测序揭示Cntnap2阳性星形胶质细胞通过破坏谷氨酸再摄取引发延髓头端血管活性肠肽区的高血压反应
Shuai Zhang,Lei Tong,Zhangyan Ren et al.
Shuai Zhang et al.
Introduction: The rostral ventrolateral medulla (RVLM) is a vital vasomotor nucleus involved in hypertension control. However, the molecular intricacies within RVLM cells, particularly in non-neuronal cell populations suc...
Association of hematopoietic loss of Y chromosome with valvular heart disease incidence and sex susceptibility [0.03%]
染色体Y丢失与瓣膜性心脏疾病发病率及性别易感性的关联性研究
Chenxuan Zhao,Yuanfeng Huang,Tianqi Ma et al.
Chenxuan Zhao et al.
Introduction: Hematopoietic mosaic Loss Of Y chromosome (LOY), a condition referring to the age-related loss of Y chromosome in a subset of blood cells, is associated with shortened life expectancy and increased risk of a...
Voxtalisib inhibits enterovirus 71 replication by downregulating host RAN and restoring IFN-STAT signaling [0.03%]
voxtalisib通过下调宿主RAN蛋白并恢复IFN-Stat信号转导抑制肠道病毒71型复制
Wang Delong,Yang Qingyu,Zhu Guangyan et al.
Wang Delong et al.
Introduction: Hand, foot, and mouth disease (HFMD) is a common enterovirus-induced illness primarily affecting children under 5 years of age. Enterovirus 71 (EV71) is a major causative agent associated with severe HFMD th...
Corrigendum to "An updated review and recent advancements in carbon-based bioactive coatings for dental implant applications" [J. Adv. Res. 72 (2025) 265-286] [0.03%]
关于“碳基生物活性涂层在牙科植入物应用中的最新进展和更新综述”的勘误修正[J. Adv. Res. 72 (2025) 265-286]
Nazrah Maher,Anum Mahmood,Muhammad Amber Fareed et al.
Nazrah Maher et al.
A cocktail hydrogel promoting the functional interneurons regeneration of human neural progenitor cells for brain injury therapy [0.03%]
一种促进人类神经干细脑损伤治疗的功能中间神经元再生的鸡尾酒水凝胶
Di Zhang,Jun Chen,Huaisong Lin et al.
Di Zhang et al.
Introduction: Traumatic Brain Injury (TBI) usually leads to substantial mortality and disability among adult populations. Neural progenitor cells (NPCs) transplantation exhibits great potential in TBI treatment. However, ...
Squalene epoxidase promotes paraquat-induced pulmonary toxicity through endoplasmic reticulum-mediated ferroptosis [0.03%]
角鲨烯环氧酶通过内质网介导的铁死亡促进百草枯诱导的肺毒性
Yanyan Zhu,Wenwen Zhao,Wan Li et al.
Yanyan Zhu et al.
Introduction: Paraquat (PQ), a widely used herbicide, causes lethal lung injury through unresolved mechanisms, posing urgent clinical challenges due to the lack of effective antidotes. ...
Cadmium targeting MLKL-Drp1 axis to trigger mitochondrial oxidative stress contributes to necroinflammation in rat kidney [0.03%]
镉通过靶向MLKL-Drp1轴触发线粒体氧化应激参与大鼠肾脏坏死性炎症
Cai-Yu Lian,Wei-Hao Xia,Ming Cheng Sun et al.
Cai-Yu Lian et al.
Introduction: Acute kidney injury (AKI) induced by cadmium (Cd) manifests excessive inflammation with no effective therapy. Necroptosis, a novel manner of necrosis that regulates cell death, has been revealed important fu...