Biological potential and mechanisms of Tea's bioactive compounds: An Updated review [0.03%]
茶叶生物活性成分的生物学潜力及机制：综述更新
Qiaoxian Luo,Longbiao Luo,Jinmin Zhao et al.
Qiaoxian Luo et al.
Background: Tea (Camellia sinensis) has a rich history and is widely consumed across many countries, and is categorized into green tea, white tea, oolong tea, yellow tea, black tea, and dark tea based on the level of ferm...
Antibody-antibiotic conjugate targeted therapy for orthopedic implant-associated intracellular S. aureus infections [0.03%]
靶向疗法治疗骨科植入物相关细胞内金黄色葡萄球菌感染
Leilei Qin,Ning Hu,Yanhao Zhang et al.
Leilei Qin et al.
Introduction: Treating orthopedic implant-associated infections, especially those caused by Staphylococcus aureus (S. aureus), remains a significant challenge. S. aureus has the ability to invade host cells, enabling it t...
The male and female genomes of golden pompano (Trachinotus ovatus) provide insights into the sex chromosome evolution and rapid growth [0.03%]
金线鱼雌雄基因组的组装及性别分化研究
Honglin Luo,Yongde Zhang,Fuyan Liu et al.
Honglin Luo et al.
Introduction: Golden pompano (Trachinotus ovatus) is economically significant important for offshore cage aquaculture in China and Southeast Asian countries. Lack of high-quality genomic data and accurate gene annotations...
An interpretable artificial intelligence framework for designing synthetic lethality-based anti-cancer combination therapies [0.03%]
一种用于设计合成致死型抗癌症联合疗法的可解释人工智能框架
Jing Wang,Yuqi Wen,Yixin Zhang et al.
Jing Wang et al.
Introduction: Synthetic lethality (SL) provides an opportunity to leverage different genetic interactions when designing synergistic combination therapies. To further explore SL-based combination therapies for cancer trea...
CircMap4k2 reactivated by aneurysm plication alleviates residual cardiac remodeling after SVR by enhancing cardiomyocyte proliferation in post-MI mice [0.03%]
通过动脉瘤折叠重新激活的CircMap4k2通过增强心肌细胞增殖减轻MI后SVR小鼠残余心脏重塑
Junyu Yan,Chenzhi Ai,Qi Chen et al.
Junyu Yan et al.
Introduction: Surgical ventricular reconstruction (SVR) is an alternative therapeutic approach in patients with refractory heart failure (HF), but residual remodeling after SVR limits the improvement of HF. Recently, we r...
Machine learning approach reveals microbiome, metabolome, and lipidome profiles in type 1 diabetes [0.03%]
机器学习方法揭示1型糖尿病微生物组、代谢组和脂质体特征
Huiling Tan,Yu Shi,Tong Yue et al.
Huiling Tan et al.
Introduction: Type 1 diabetes (T1D) is a complex disorder influenced by genetic and environmental factors. The gut microbiome, the serum metabolome, and the serum lipidome have been identified as key environmental factors...
SIRT1, a target of miR-708-3p, alleviates fluoride-induced neuronal damage via remodeling mitochondrial network dynamics [0.03%]
SIRT1通过重塑线粒体网络动力学缓解氟诱导的神经元损伤（miR-708-3p靶点）
Qian Zhao,Guo-Yu Zhou,Qiang Niu et al.
Qian Zhao et al.
Introduction: Neurological dysfunction induced by fluoride contamination is still one of major concern worldwide. Recently, neuroprotective roles of silent information regulator 1 (SIRT1) focusing on mitochondrial functio...
CORM‑2 reduces cisplatin accumulation in the mouse inner ear and protects against cisplatin-induced ototoxicity [0.03%]
CORM-2减少小鼠内耳顺铂累积并保护其免受顺铂引起的耳毒性影响
Ah-Ra Lyu,Soo Jeong Kim,Min Jung Park et al.
Ah-Ra Lyu et al.
Introduction: Cisplatin is a life-saving anticancer compound used to treat multiple solid malignant tumors, while it causes permanent hearing loss. There is no known cure, and the FDA has not approved any preventative tre...
Ten metabolites-based algorithm predicts the future development of type 2 diabetes in Chinese [0.03%]
基于10种代谢产物的算法预测中国人群2型糖尿病的发生风险
Xiuli Su,Chloe Y Y Cheung,Junda Zhong et al.
Xiuli Su et al.
Introduction: Type 2 diabetes (T2D) is a heterogeneous metabolic disease with large variations in the relative contributions of insulin resistance and β-cell dysfunction across different glucose tolerance subgroups and e...
Laser additive manufacturing of shape memory biopolymer bone scaffold: 3D conductive network construction and electrically driven mechanism [0.03%]
激光增材制造形状记忆生物聚合物骨支架：三维导电网络构建及电驱动机制研究
Cijun Shuai,Zhicheng Wang,Feng Yang et al.
Cijun Shuai et al.
Introduction: The electro-actuated shape memory polymer scaffold has gained increasing attentions on the utilization of minimally invasive surgery for bone defect repair, which requires to construct an efficient conductiv...