Lactylation: a promising target for musculoskeletal disorders via interactions with chronic inflammation [0.03%]
乳酰化通过与慢性炎症相互作用成为治疗肌肉骨骼疾病的新靶点
Tiantian Wang,Sihan Chen,Zhen Hong
Tiantian Wang
Musculoskeletal disorders (MSDs) encompass conditions that affect bones, joints, and muscles, leading to substantial pain and functional impairment and representing a major global health concern. In MSDs, key metabolic processes-such as gly...
Corrigendum to "Erianin serves as an NFATc1 inhibitor to prevent breast cancer-induced osteoclastogenesis and bone destruction" Adv. Res. 69 (2025) 399-411] [0.03%]
“姜黄素通过抑制NFATC1的活性防止乳腺癌诱发破骨细胞生成和骨破坏”的勘误(Adv.Res.69(2025)399-411)
Jiehuang Zheng,Weili He,Yan Chen et al.
Jiehuang Zheng et al.
The dual fate of L-theanine in tea: Metabolic regulation and processing transformations [0.03%]
茶氨酸的双重命运：代谢调控与加工转化
Haiyan Cheng,Jinglei Zheng,Linyue Tu et al.
Haiyan Cheng et al.
Background: L-Theanine, the signature non-protein amino acid unique to tea (Camellia sinensis), is crucial for tea's health benefits and umami taste, yet its biosynthesis and stability face increasing threats from climate...
A predator-prey interaction between myxobacteria and fungi mediated by outer membrane vesicles [0.03%]
黏细菌通过外膜囊泡介导的真菌捕食作用
Jihong Wang,Xiangrui Guo,Qiwen Fan et al.
Jihong Wang et al.
Introduction: Outer membrane vesicles (OMVs) of Gram-negative bacteria mediate diverse functions in natural ecosystems. As a keystone taxon in soil, myxobacteria produce OMVs for cargo packing and microbial predation. How...
Hydrogen sulfide regulation in redox homeostasis and programmed cell death: mechanistic insights and implications in cancer [0.03%]
氢硫化物在氧化还原平衡和程序性细胞死亡中的调节：机制见解及其对癌症的影响
Aoli Deng,Lulu Chen,Hangqi Huang et al.
Aoli Deng et al.
Hydrogen sulfide (H2S), a key endogenous gaseous mediator derived from sulfur-containing amino acid metabolism, exhibits a concentration-dependent duality in cancer. At physiological concentrations, H2S exerts antioxidant effects by activat...
Genome-wide CRISPR screen identifies STK11 as a critical regulator of sialic acid clusters important for influenza A virus attachment [0.03%]
基因组范围的CRISPR筛选鉴定出STK11是调控流感病毒吸附的重要糖神经氨酸簇的关键调节因子
Huimin Sun,Jiahui Zou,Shaoyu Tu et al.
Huimin Sun et al.
Introduction: Swine influenza virus (SIV) is a highly contagious respiratory pathogen in pigs that causes substantial economic losses in the pig industry. Importantly, pigs act as "mixing vessels" for diverse influenza A ...
Role of capsaicin, circadian clock genes, and TRPV1 in colorectal carcinogenesis: Lessons and future directions [0.03%]
辣椒素、昼夜钟基因和TRPV1在结直肠癌发生中的作用：经验与未来发展方向
Qiuyan Zhang,Yujia Lu,Yuchen Zhao et al.
Qiuyan Zhang et al.
Disruptions in rhythm-regulating genes, termed circadian misalignment, have been increasingly associated with the progression of colorectal cancer (CRC), a significant global health challenge. Capsaicin (CAP), a bioactive compound found in ...
Yanhong Fu,Tong Yu,Xiao Ma et al.
Yanhong Fu et al.
Introduction: The Apiales order harbors a rich variety of species, including vegetables, spices, and medicinal herbs, that possess diverse morphological characteristics and are globally distributed. Apiaceae and Araliacea...
Accurate fatty liver disease diagnosis with a multi-source feature fusion model on the segmented tongue image dataset [0.03%]
基于分割舌象图像数据的肝病多模态特征融合诊断模型研究
Jie Gao,Tao Chen,Yong Xu et al.
Jie Gao et al.
Introduction: More than 100 million individuals in rural areas of China are suffered from Fatty Liver Disease (FLD). However, health clinics in remote regions often lack the necessary professional expertise and expensive ...
The significance of urine extracellular vesicle DNA methylation detection in the diagnosis and classification of prostate cancer [0.03%]
尿液外泌体DNA甲基化检测在前列腺癌诊断和分型中的意义
Ting Ding,Yanjun Diao,Ruiqing Fu et al.
Ting Ding et al.
Introduction: As one of the most common malignant tumors in men, prostate cancer (PCa) still lacks convenient, non-invasive and highly specific diagnostic markers. The advantages of Extracellular vesicle (EV) DNA in tumor...