Tetrahydroxy stilbene glucoside rejuvenates aging hematopoietic stem cells with predilection for lymphoid differentiation via AMPK and Tet2 [0.03%]
四羟基茋通过AMPK和Tet2改善造血干细胞老化及淋巴系分化倾向
Dan Gao,Wei-Wei Yi,Bo Liu et al.
Dan Gao et al.
Introduction: Aging of hematopoietic stem cells (HSCs) has emerged as an important challenge to human health. Recent advances have raised the prospect of rejuvenating aging HSCs via specific medical interventions, includi...
Bridging the gap: Integrating exercise mimicry into chronic disease management through suppressing chronic inflammation [0.03%]
跨越鸿沟：通过抑制慢性炎症将运动模拟融入慢性疾病管理中
Mohammad Nasb,Fengxing Li,Lamis Dayoub et al.
Mohammad Nasb et al.
Background: Chronic inflammation is a common hallmark of many chronic diseases. Although exercise holds paramount importance in preventing and managing chronic diseases, adherence to exercise programs can be challenging f...
Yun Liu,Zifang Wu,Yikun Li et al.
Yun Liu et al.
Background: Endothelial cell (EC) metabolism plays a crucial role in the process of angiogenesis. Intrinsic metabolic events such as glycolysis, fatty acid oxidation, and glutamine metabolism, support secure vascular migr...
MIER2/PGC1A elicits sunitinib resistance via lipid metabolism in renal cell carcinoma [0.03%]
MiT2/PGC1α通过脂质代谢介导肾细胞癌的舒尼替尼耐药性
Zhihao Wei,Yuzhong Ye,Chenchen Liu et al.
Zhihao Wei et al.
Introduction: Renal cell carcinoma (RCC) is one of the most common malignant tumors of the urinary system and accounts for more than 90 % of all renal tumors. Resistance to targeted therapy has emerged as a pivotal factor...
Tanshinone IIA alleviates pulmonary fibrosis by modulating glutamine metabolic reprogramming based on [U-13C5]-glutamine metabolic flux analysis [0.03%]
基于[U-13C5]谷氨酰胺代谢流分析的大黄素甲醚通过调节谷氨酰胺代谢重编程缓解肺纤维化
Baixi Shan,Congying Guo,Haoyan Zhou et al.
Baixi Shan et al.
Introduction: Glutamine metabolic reprogramming, mediated by glutaminase (GLS), is an important signal during pulmonary fibrosis (PF) progression. Tanshinone IIA (Tan IIA) is a naturally lipophilic diterpene with antioxid...
Corrigendum to "Lung-specific homing of diphenyleneiodonium chloride improves pulmonary fibrosis by inhibiting macrophage M2 metabolic program" [J. Adv. Res. 44 (2023) 213-225] [0.03%]
“二苯基碘鎓氯化物特异性靶向肺部可改善由抑制巨噬细胞M2代谢程序引起的肺纤维化”[J. Adv. Res. 44 (2023) 213-225]的勘误通知
Huirui Wang,Yinghui Gao,Li Wang et al.
Huirui Wang et al.
Published Erratum
Journal of advanced research. 2024 May:59:223. DOI:10.1016/j.jare.2024.04.006 2024
Exploring melatonin's multifaceted role in female reproductive health: From follicular development to lactation and its therapeutic potential in obstetric syndromes [0.03%]
褪黑素在女性生殖健康中的多重作用：从卵泡发育到泌乳及其在妇科学综合征治疗中的潜力
Qihui Li,Tenghui Zheng,Jiaming Chen et al.
Qihui Li et al.
Background: Melatonin is mainly secreted by the pineal gland during darkness and regulates biological rhythms through its receptors in the suprachiasmatic nucleus of the hypothalamus. In addition, it also plays a role in ...
Study on PTFE superhydrophobic coating modified by IC@dMSNs and its enhanced antibacterial effect [0.03%]
IC@dMSNs改性PTFE超疏水涂层及其抗菌性能研究
Weixing Zhang,Juan Du,Fariha Kanwal et al.
Weixing Zhang et al.
Introduction: Vascular catheter-related infections and thrombosis are common and may lead to serious complications after catheterization. Reducing the incidence of such infections has become a significant challenge. ...
KRAS/PI3K axis driven GTF3C6 expression and promotes LUAD via FAK pathway [0.03%]
KRAS/PI3K轴驱动的GTF3C6表达通过FAK途径促进LUAD的发展
Xingzhao Ji,Mingqiang Liu,Tianyi Zhang et al.
Xingzhao Ji et al.
Introduction: Effective targeting drugs for KRAS mutation-mediated Lung Adenocarcinoma (LUAD) are currently are limited. Objectives: In...
Tolerogenic dendritic cell-mediated regulatory T cell differentiation by Chinese herbal formulation attenuates colitis progression [0.03%]
基于中药方剂诱导调节性T细胞分化抑制结肠炎的耐受型树突状细胞机制研究
Chunhua Huang,Cheng Lyu,Heung-Lam Mok et al.
Chunhua Huang et al.
Introduction: Ulcerative colitis (UC) is a chronic inflammatory disease characterized by loss of immune tolerance to luminal antigens and progressive intestinal tissue injury. Thus, the re-establishment of immune toleranc...