Dekun Kong,Li Cui,Xiaozheng Wang et al.
Dekun Kong et al.
Introduction: Plant-fungal interactions stimulate endophytic fungi to produce a plethora of metabolites that enhance plant growth and improve stress resistance. Opines, naturally occurring compounds formed through the con...
Trends, clinicopathological features, surgical treatment patterns and prognoses of early-onset versus late-onset gastric cancer: A retrospective cohort study [0.03%]
早期与晚期胃癌的流行趋势、临床病理特征、手术治疗模式及预后：一项回顾性队列研究
Yingxue Liu,Xiaoyan Zhang,Lu Gan et al.
Yingxue Liu et al.
Introduction: This study investigates the differences between early-onset gastric carcinoma (EOGC) and late-onset gastric carcinoma (LOGC) by examining trends, demographics, clinical and molecular features, treatments, an...
Interleukin-10 deficiency suppresses colorectal cancer metastasis by enriching gut Parabacteroides distasonis [0.03%]
肠道菌Parabacteroides distasonis通过抑制IL-10缺乏小鼠结直肠癌转移发挥肿瘤抑制作用
Jing Yu,Lili Feng,Zhanhao Luo et al.
Jing Yu et al.
Introduction: The intricate interplay of interleukin-10 (IL-10) and gut microbiota influences tumor development and progression, yet the impacts on colorectal cancer (CRC) metastasis remain incompletely understood. ...
miR-3606-3p alleviates skin fibrosis by integratively suppressing the integrin/FAK, p-AKT/p-ERK, and TGF-β signaling cascades [0.03%]
微RNA miR-3606-3p通过整合抑制整联蛋白/FAK、p-AKT/p-ERK和TGF-β信号级联回归皮肤纤维化
Yahui Chen,Yiyi Gong,Mengkun Shi et al.
Yahui Chen et al.
Introduction: Fibroblast abnormalities are crucial causes of skin fibrosis, including systemic sclerosis (SSc) and keloids. However, their mechanisms, including underlying microRNA regulatory mechanisms, remain elusive. ...
An accurate prediction for respiratory diseases using deep learning on bronchoscopy diagnosis images [0.03%]
基于支气管镜诊断图像的深度学习准确预测呼吸系统疾病的发展趋势与严重程度
Weiling Sun,Pengfei Yan,Minglei Li et al.
Weiling Sun et al.
Introduction: Bronchoscopy is of great significance in diagnosing and treating respiratory illness. Using deep learning, a diagnostic system for bronchoscopy images can improve the accuracy of tracheal, bronchial, and pul...
Self-adhesion conductive cardiac patch based on methoxytriethylene glycol-functionalized graphene effectively improves cardiac function after myocardial infarction [0.03%]
基于甲氧基三乙二醇功能化石墨烯的自粘附导电心脏补片可有效改善心肌梗死后的心脏功能
Xu Wang,Hao Wang,Xin Liu et al.
Xu Wang et al.
Introduction: Abnormal electrical activity of the heart following myocardial infarction (MI) may lead to heart failure or sudden cardiac death. Graphene-based conductive hydrogels can simulate the microenvironment of myoc...
Bacteroides uniformis ameliorates pro-inflammatory diet-exacerbated colitis by targeting endoplasmic reticulum stress-mediated ferroptosis [0.03%]
丁酸梭菌通过靶向内质网应激介导的铁死亡缓解促炎饮食加重的结肠炎
Caiguang Liu,Linxin Liu,Zhenyi Tian et al.
Caiguang Liu et al.
Introduction: A pro-inflammatory diet is positively associated with the risk and progression of inflammatory bowel diseases (IBD). Recently, ferroptosis has been observed in patients with different dietary patterns-associ...
Kaempferol regulating macrophage foaming and atherosclerosis through Piezo1-mediated MAPK/NF-κB and Nrf2/HO-1 signaling pathway [0.03%]
山柰酚通过Piezo1介导的MAPK/NF-κB和Nrf2/HO-1信号通路调节巨噬细胞泡沫化及动脉粥样硬化形成
Tianjiao Chu,Yuman Wang,Shihao Wang et al.
Tianjiao Chu et al.
Introduction: Antioxidants represented by kaempferol have been shown to be effective against atherosclerosis (AS). However, the underlying mechanisms still remain unclear. ...
Generalized deep learning for histopathology image classification using supervised contrastive learning [0.03%]
基于监督对比学习的病理图像分类通用深度学习方法
Md Mamunur Rahaman,Ewan K A Millar,Erik Meijering
Md Mamunur Rahaman
Introduction: Cancer is a leading cause of death worldwide, necessitating effective diagnostic tools for early detection and treatment. Histopathological image analysis is crucial for cancer diagnosis but is often hindere...
Transient receptor potential channels in viral infectious diseases: Biological characteristics and regulatory mechanisms [0.03%]
病毒感染性疾病中的瞬时受体电位通道生物学特性及调控机制
Wen-Hui Qi,Na Tang,Zhi-Jing Zhao et al.
Wen-Hui Qi et al.
Background: Viral infectious diseases have long posed a challenge to humanity. In recent decades, transient receptor potential (TRP) channels have emerged as newly investigated cation channels. Increasing evidence suggest...