Association of intestinal anti-inflammatory drug target genes with psychiatric Disorders: A Mendelian randomization study [0.03%]
肠道抗炎药物靶点基因与精神障碍的关联：一项孟德尔随机化研究
Guorui Zhao,Zhe Lu,Yundan Liao et al.
Guorui Zhao et al.
Introduction: Psychiatric disorders present a substantial global public health burden with limited drug options. The gut-brain axis connects inflammatory bowel diseases and psychiatric disorders, which often have comorbid...
Single-nucleus transcriptional and chromatin accessible profiles reveal critical cell types and molecular architecture underlying chicken sex determination [0.03%]
单细胞核转录组和染色质可及性揭示性别决定关键细胞类型及分子机制
Jianbo Li,Xiuan Zhang,Xiqiong Wang et al.
Jianbo Li et al.
Introduction: Understanding the sex determination mechanisms in birds has great significance for the biological sciences and production in the poultry industry. Sex determination in chickens is a complex process that invo...
Mesenchymal stem cell secretome for regenerative medicine: Where do we stand? [0.03%]
间充质干细胞分泌组在再生医学中的应用：我们目前处于什么水平？
Catarina M Trigo,Joana S Rodrigues,Sérgio P Camões et al.
Catarina M Trigo et al.
Background: Mesenchymal stem cell (MSC)-based therapies have yielded beneficial effects in a broad range of preclinical models and clinical trials for human diseases. In the context of MSC transplantation, it is widely re...
The hiPSC-derived corneal endothelial progenitor-like cell recovers the rabbit model of corneal endothelial dystrophy [0.03%]
基于hiPSC的角膜内皮前体样细胞修复兔角膜内皮营养不良模型研究
Yi-Jen Hsueh,Hung-Chi Chen,Yu-Yun Pan et al.
Yi-Jen Hsueh et al.
Introduction: Corneal endothelial dysfunction results in cornea opacity, damaging sightedness, and affecting quality of life. A corneal transplant is the current effective intervention. Due to the scarcity of donated corn...
Sodium citrate targeting Ca2+/CAMKK2 pathway exhibits anti-tumor activity through inducing apoptosis and ferroptosis in ovarian cancer [0.03%]
柠檬酸钠通过诱导卵巢癌细胞凋亡和铁死亡发挥抗肿瘤作用并靶向Ca2+/CAMKK2通路
Yulun Wu,Chaoran Jia,Wei Liu et al.
Yulun Wu et al.
Introduction: Ovarian cancer (OC) is known for its high mortality rate. Although sodium citrate has anti-tumor effects in various cancers, its effect and mechanism in OC remain unclear. ...
Crosstalk between endothelial cells and dermal papilla entails hair regeneration and angiogenesis during aging [0.03%]
内皮细胞与毛乳头细胞的相互作用在衰老期间促进头发再生和血管生成
Siyi Zhou,Zeming Li,Xinzhu Li et al.
Siyi Zhou et al.
Introduction: Tissues maintain their function through interaction with microenvironment. During aging, both hair follicles and blood vessels (BV) in skin undergo degenerative changes. However, it is elusive whether the ch...
Zoophytophagous predator sex pheromone and visual cues of opposing reflectance spectra lure predator and invasive prey [0.03%]
兼食植食性捕食者的性信息素和反射光谱相反的视觉线索吸引捕食者和入侵猎物
Bashiru Adams,Fathiya Mbarak Khamis,Abdullahi Ahmed Yusuf et al.
Bashiru Adams et al.
Introduction: In sub-Saharan Africa, the invasive South American leafminer Phthorimaea absoluta is the most damaging tomato pest. Females of the pest can reproduce both sexually and through parthenogenesis and lay their e...
Chen Qian,Qing Wang,Yusen Qiao et al.
Chen Qian et al.
Background: Arachidonic acid (AA), one of the most ubiquitous polyunsaturated fatty acids (PUFAs), provides fluidity to mammalian cell membranes. It is derived from linoleic acid (LA) and can be transformed into various b...
Associations between per- and polyfluoroalkyl chemicals and abdominal aortic calcification in middle-aged and older adults [0.03%]
全氟和多氟化合物与中老年人腹主动脉钙化的关联研究
Jijingru Yang,Tian Wang,Kai Li et al.
Jijingru Yang et al.
Introduction: Per- and polyfluoroalkyl substances (PFAS) have infiltrated countless everyday products, raising concerns about potential effects on human health, specifically on the cardiovascular system and the developmen...
Exploring the role of parthanatos in CNS injury: Molecular insights and therapeutic approaches [0.03%]
细胞质DNA免疫传感器在脓毒症中的作用及机制研究
Jiacheng Zhang,Xinli Hu,Yibo Geng et al.
Jiacheng Zhang et al.
Background: Central nervous system (CNS) injury causes severe organ damage due to both damage resulting from the injury and subsequent cell death. However, there are currently no effective treatments for countering the ir...