GYY4137-induced p65 sulfhydration protects synovial macrophages against pyroptosis by improving mitochondrial function in osteoarthritis development [0.03%]
GYY4137诱导的p65硫化修饰通过改善线粒体功能来保护软骨下巨噬细胞免受焦亡以促进骨关节炎发展
Jun Ma,Peng Yang,Zhibin Zhou et al.
Jun Ma et al.
Introduction: Osteoarthritis (OA) is the most common arthritis that is characterized by the progressive synovial inflammation and loss of articular cartilage. Although GYY4137 is a novel and slow-releasing hydrogen sulfid...
Multi-task aquatic toxicity prediction model based on multi-level features fusion [0.03%]
基于多级特征融合的多任务水质毒性预测模型
Xin Yang,Jianqiang Sun,Bingyu Jin et al.
Xin Yang et al.
Introduction: With the escalating menace of organic compounds in environmental pollution imperiling the survival of aquatic organisms, the investigation of organic compound toxicity across diverse aquatic species assumes ...
Khaled Amer,Neveen A Soliman,Sameh Soror et al.
Khaled Amer et al.
Background: Studying the human genome is crucial to embrace precision medicine through tailoring treatment and prevention strategies to the unique genetic makeup and molecular information of individuals. After human genom...
Prevention and treatment of antibiotics-associated adverse effects through the use of probiotics: A review [0.03%]
益生菌在预防和治疗抗生素相关不良反应中的作用：综述性文章
Shuwei Yang,Jiaqi Qiao,Meng Zhang et al.
Shuwei Yang et al.
Background: The human gut hosts a diverse microbial community, essential for maintaining overall health. However, antibiotics, commonly prescribed for infections, can disrupt this delicate balance, leading to antibiotic-a...
Yakong Wang,Xiangyang Sun,Jun Peng et al.
Yakong Wang et al.
Background: The whole life of a plant is regulated by complex environmental or hormonal signaling networks that control genomic stability, environmental signal transduction, and gene expression affecting plant development...
IDD10-NAC079 transcription factor complex regulates sheath blight resistance by inhibiting ethylene signaling in rice [0.03%]
水稻IDD10-NAC079转录因子复合体通过抑制乙烯信号提高抗稻瘟病性
Zhuo Li,Huan Chen,De Peng Yuan et al.
Zhuo Li et al.
Introduction: Rhizoctonia solani Kühn is a pathogen causing rice sheath blight (ShB). Ammonium transporter 1 (AMT1) promotes resistance of rice to ShB by activating ethylene signaling. However, how AMT1 activates ethylen...
Fucoidan alleviates high sucrose-induced metabolic disorders and enhances intestinal homeostasis through modulation of Notch signaling [0.03%]
岩藻糖硫酸酯通过调节诺特定理信号缓解高果糖诱导的代谢紊乱和增强肠道稳态
Jian Liu,Weiqiang Xia,Qifang Wu et al.
Jian Liu et al.
Introduction: The therapeutic potential of fucoidan (FUC), a natural polysaccharide, in metabolic disorders is recognized, yet its underlying mechanisms remain unclear. ...
N-succinyl-chitosan as ecofriendly pesticide carriers: Nano encapsulation and synergistic antifungal effect on 4-hydroxyphenyl-2-propenyl-1-one derivatives based on chalcone structure [0.03%]
基于查尔酮结构的4-羟基苯基-2-丙烯基-1-酮衍生物的协同抗真菌作用及N-环状碳酸乙二酯壳聚糖作为环境友好型农药载体的研究
Zhi Xia,Qing Zhou,Yu Zhang et al.
Zhi Xia et al.
Introduction: Traditional pesticides have poor-water solubility, high toxicity and low bioavailability. Therefore, it is of great significance for the sustainable and healthy development of the pesticide industry to devel...
Unlocking the crucial role of cancer-associated fibroblasts in tumor metastasis: Mechanisms and therapeutic prospects [0.03%]
癌相关成纤维细胞在肿瘤转移中的关键作用：机制和治疗前景
Yingxue Liu,Xiaoyan Zhang,Wenchao Gu et al.
Yingxue Liu et al.
Background: Tumor metastasis represents a stepwise progression and stands as a principal determinant of unfavorable prognoses among cancer patients. Consequently, an in-depth exploration of its mechanisms holds paramount ...
Sympathetic hyperinnervation drives abdominal aortic aneurysm development by promoting vascular smooth muscle cell phenotypic switching [0.03%]
交感神经支配通过促进血管平滑肌细胞表型转换来驱动腹主动脉瘤的发展
Zhenquan Tang,Jingfang Xie,Ming Jin et al.
Zhenquan Tang et al.
Introduction: Sympathetic hyperinnervation plays an important role in modulating the vascular smooth muscle cell (VSMC) phenotype and vascular diseases, but its role in abdominal aortic aneurysm (AAA) is still unknown. ...