Gastrointestinal traits, common inflammatory disorders, gallstones, and biliary tract cancer: A network Mendelian randomization study [0.03%]
胃肠道特征，常见炎症疾病，胆结石和胆道癌症的关联：一项网络孟德尔随机化研究
Ye Bai,Min Zhang,Lin Chen et al.
Ye Bai et al.
Introduction: Observational studies have shown that gallstone disease (GSD), cholecystitis, cholangitis, polyp of gallbladder, viral hepatitis, pancreatitis and gastrointestinal (GI) traits such as H. pylori infection, in...
SRSF9 mediates oncogenic RNA splicing of SLC37A4 via liquid-liquid phase separation to promote oral cancer progression [0.03%]
SRSF9通过液-液相分离介导SLC37A4的致癌RNA剪接以促进口腔癌症进展
Qiu Peng,Lujuan Wang,Ying Long et al.
Qiu Peng et al.
Introduction: Oral cancer represents a significant proportion of head and neck malignancies, accounting for approximately 3 % of all malignant tumors worldwide. ...
Reshaped local microbiology metabolism by raw tea according to pile fermentation in the dark tea [0.03%]
原料茶对黑茶渥堆发酵中微生物代谢途径的影响
Yating Guo,Yani Pan,Xinyu Feng et al.
Yating Guo et al.
Introduction: Traditionally, the mechanism of dark tea quality formation has centered on microorganisms, with quality regulated by manipulating microorganisms and their fermentation environment. Nevertheless, raw teas, th...
From inflammation to remodelling: A novel BASP1+ monocyte subset as a catalyst for acute aortic dissection [0.03%]
从炎症到重塑：BASP1+单核细胞亚群作为急性主动脉夹层的催化剂
Wenhui He,Sanjiu Yu,Jun Li et al.
Wenhui He et al.
Introduction: Monocytes comprise heterogeneous cell populations. However, beyond traditionally considered as precursors of tissue macrophages, heterogeneity and detailed effects of monocytes in acute aortic dissection (AA...
Endophyte Acrocalymma vagum establishes the holobiont with rice to attract beneficial microorganisms and promote disease resistance [0.03%]
内生菌Acrocalymma vagum与水稻建立共生体以吸引有益微生物并促进疾病抵抗能力
Yulan Zeng,Xuanjun Lu,Mengrong Wang et al.
Yulan Zeng et al.
Introduction: Endophytic fungi are essential microorganisms in promoting plant health. However, the mechanism of endophytic fungi regulating root microbiota to enhance crop production and resistance remains unclear. ...
The LRP1-SHP2 pathway regulates TRPV1 sensitivity in the peripheral nervous system: Insights from amyloid beta 1-42 modulation [0.03%]
LRP1-SHP2通路调节外周神经系统中的TRPV1敏感性：来自淀粉样蛋白β1-42调节的见解
Sung-Min Hwang,Jueun Roh,Eun Jin Go et al.
Sung-Min Hwang et al.
Introduction: Mature adults often exhibit higher pain thresholds than younger individuals. However, this phenomenon is poorly understood, especially with regards to peripheral nervous system signaling. ...
The Power of Exercise: Unlocking the biological Mysteries of Peripheral-Central crosstalk in Parkinson's disease [0.03%]
运动的力量：揭示帕金森病周围-中枢交叉沟通的生物奥秘
Jingwen Li,Tingting Liu,Meiyan Xian et al.
Jingwen Li et al.
Background: Exercise is a widely recognized non-pharmacological treatment for Parkinson's Disease (PD). The bidirectional regulation between the brain and peripheral organs has emerged as a promising area of research, wit...
Nutrient supplementation mitigates retinal dysfunction in Acox1 knockout mice with impaired peroxisomal fatty acid oxidation [0.03%]
ACOX1敲除小鼠视网膜功能障碍揭示过氧化物酶体脂肪酸氧化障碍导致的视网膜营养不良及其补充治疗前景
Myriam Boeck,Hitomi Yagi,Chuck T Chen et al.
Myriam Boeck et al.
Introduction: Dyslipidemia contributes to many retinal diseases, but underlying lipid processing pathways are not fully understood. Peroxisomes oxidize very long-chain fatty acids and generate docosahexaenoic acid (DHA). ...
Saccharide mapping apparatus for real-time PAGE detection of polysaccharides [0.03%]
用于实时检测多糖的PAGE蔗糖映射装置
Baojie Zhu,Jing Zhao,Shaoping Li
Baojie Zhu
Introduction: As a key technique in saccharide mapping, polysaccharides analysis using carbohydrate gel electrophoresis (PACE) analysis platform has always been self-assembled and built in various laboratories independent...
Cracking melanoma's armor: Supramolecular dual-strike on XPO1 and β-catenin to overcome resistance [0.03%]
cracking melanoma's armor: Supramolecular dual-strike on XPO1 and β-catenin to overcome resistance：击破黑色素瘤的盔甲：通过XPO1和β-连环蛋白的超分子双重攻击来克服耐药性
Yinliang Lu,Ruishan Guo,Wenfei Song et al.
Yinliang Lu et al.
Introduction: XPO1 plays a crucial role in the nuclear export machinery, making it an attractive target for inhibiting nuclear-cytoplasmic transport in melanoma, where its overexpression is linked to unfavorable prognosis...