Chromosome-level genome provides novel insights into the starch metabolism regulation and evolutionary history of Tetraselmis helgolandica [0.03%]
染色体水平基因组为海藻Tetraselmis helgolandica的淀粉代谢调控和进化史提供了新的见解
Zuodong Zhou,Jiawei E,Qianwen Shi et al.
Zuodong Zhou et al.
Introduction: Tetraselmis helgolandica is a marine microalga belonging to the Chlorophyta phylum. It is widely distributed in the coastal waters of Asia and is commonly used as aquatic feed. T. helgolandica is characteriz...
Inosine monophosphate overcomes the coexisting resistance of mcr-1 and blaNDM-1 in Escherichia coli [0.03%]
鸟苷酸单磷酸能够克服携带mcr-1和blaNDM-1的Escherichia coli共存的耐药性
Liang Zhao,Jian Xu,Saiwa Liu et al.
Liang Zhao et al.
Introduction: The rise of antibiotic-resistant bacteria, particularly those harboring mcr-1 and blaNDM-1, threatens public health by reducing the efficacy of colistin and carbapenems. Recently, the co-spread of mcr-1 and ...
MdHMGB15-MdXERICO-MdNRP module mediates salt tolerance of apple by regulating the expression of salt stress-related genes [0.03%]
MdHMGB15-MdXERICO-MdNRP模块通过调节与盐度胁迫相关基因的表达介导苹果耐盐性
Ran-Xin Liu,Shan-Shan Li,Qian-Yu Yue et al.
Ran-Xin Liu et al.
Introduction: Soil salinity is an important limiting factor for plant growth. As a RING-type E3 ubiquitin ligase, MdXERICO is highly responsive to salt stress and can enhance the salt tolerance of plants. However, the mol...
Blood metabolites mediate causal inference studies on the effect of gut microbiota on the risk of vascular calcification [0.03%]
血液代谢物介导了关于肠道微生物组对血管钙化风险影响的因果推断研究
Aoran Huang,Jianshuai Ma,Huijin Zhu et al.
Aoran Huang et al.
Background: Emerging evidence indicates a notable connection between gut microbiota and Vascular Calcification (VC). Gut microbiota influences various disease processes through host metabolic pathways; however, the causat...
Plant extracellular vesicles as emerging neuroprotective agents for central nervous system disorders [0.03%]
植物胞外囊泡作为中枢神经系统疾病新兴的神经营养因子
Yuanyuan Yu,Zhifeng Xu,Le Xu et al.
Yuanyuan Yu et al.
Background: Plant extracellular vesicles (PEVs) have emerged important roles in central nervous system (CNS) disorders. PEVs are nanoscale vesicles (30-150 nm) that mediate intercellular communication and exhibit unique t...
Exploring the role of endogenous and exogenous silicon in reducing arsenic accumulation in rice: A multi-scale hydroponic to field study [0.03%]
内源性和外源性硅在减少水稻中砷积累中的作用探索：从水培到田间多尺度研究
Yuepeng Yin,Mengfan Jia,Ping Li et al.
Yuepeng Yin et al.
Introduction: Traditionally, Silicon (Si) fertilizers are applied externally to the soil or sprayed on the leaves to reduce rice's arsenic (As) accumulation. However, in practical agricultural production, the economic ben...
Transducin-like enhancer of split 3 protects against lipopolysaccharide-induced inflammation through DDX5-ATF1-PPP2R5A signaling [0.03%]
类似于转导的分裂增强子3通过DDX5-ATF1-PPP2R5A信号传导保护脂多糖诱导的炎症反应
Di Fan,Yi Zhong,Yin Dong et al.
Di Fan et al.
Introduction: Sepsis consists of life-threatening multi-organ dysfunction caused by an excessive systemic inflammatory response to infection. Therefore, identifying negative regulators of innate inflammation is crucial fo...
From repellent to risk: DEET's adverse effects on hormones and bone health in kids [0.03%]
从驱避剂到风险：DEET对儿童荷尔蒙和骨骼健康的不良影响
Xinyu Zhu,Wanlu Liu,Baihao Lin et al.
Xinyu Zhu et al.
Introduction: Early life bone accumulation, which predicts future fragility fracture risk, is intimately associated with sex hormones. N, N-diethyl-3-methylbenzamide (DEET) is the primary and most effective active ingredi...
Pathogenicity of novel GLA gene missense mutations in Fabry disease and the therapeutic impact of migalastat [0.03%]
费布里病中GLA基因错义突变的新致病性以及 Migalastat的治疗效果
Wenkai Guo,Pengcheng Ji,Yaqing Li et al.
Wenkai Guo et al.
Introduction: Fabry disease, a rare X-linked hereditary lysosomal storage disorder caused by mutations in the GLA gene, affecting multiple organs. However, functional validation data on the pathogenicity of newly identifi...
A mouse model of sepsis-associated DIC induced by Kappa-carrageenan and Lipopolysaccharides: Establishment and characteristics [0.03%]
κ-卡拉胶和脂多糖诱导的脓毒症相关DIC小鼠模型的建立及特点
Ping Tang,Boning Huang,Qianqing Ou et al.
Ping Tang et al.
Background: No animal models fully replicate the pathogenesis and clinical features of sepsis-associated disseminated intravascular coagulation (DIC), which hinders mechanistic understanding and treatment development. Kap...