Synergistic potentiation of the anti-metastatic effect of a Ginseng-Salvia miltiorrhiza herbal pair and its biological ingredients via the suppression of CD62E-dependent neutrophil infiltration and NETformation [0.03%]
通过抑制CD62E依赖的中性粒细胞浸润和NET形成协同增强人参-丹参药对及其生物活性成分的抗转移效果
Keqin Lu,Yawen Xia,Peng Cheng et al.
Keqin Lu et al.
Introduction: The combination of the roots of ginseng and Salvia miltiorrhiza is an effective approach for treating metastatic cancer in patients with Qi stagnation and blood stasis patterns. However, the molecular mechan...
Dihydrokoumine, a dual-target analgesic with reduced side effects isolated from a traditional Chinese medicine [0.03%]
来源于传统中药的低副作用双靶标镇痛活性成分二氢厚朴酚
Dian Liu,Jixia Wang,Tao Hou et al.
Dian Liu et al.
Introduction: Opioids are the most common antinociceptive drugs, but long-term administration causes serious adverse side effects. Gelsemium elegans Benth. is traditionally used as an analgesic agent and mainly contains i...
Regulatory balance between ear rot resistance and grain yield and their breeding applications in maize and other crops [0.03%]
抗茎腐病和产量的平衡及其在玉米等作物育种中的应用
Zechao Yin,Xun Wei,Yanyong Cao et al.
Zechao Yin et al.
Background: Fungi are prevalent pathogens that cause substantial yield losses of major crops. Ear rot (ER), which is primarily induced by Fusarium or Aspergillus species, poses a significant challenge to maize production ...
Yu-Lin Li,Bo-Yan Chen,Ze-Hao Feng et al.
Yu-Lin Li et al.
Introduction: The significance of oral/gut microbiota in acute myocardial infarction (AMI) has been increasingly appreciated. However, correlations between oral/gut microbiota and AMI parameter, as well as the key microbi...
Neural and molecular investigation into the paraventricular thalamus for chronic restraint stress induced depressive-like behaviors [0.03%]
与慢性束缚应激诱发的抑郁样行为相关的底丘脑核的神经和分子学研究
Yong He,Yikun Ren,Xiangyu Chen et al.
Yong He et al.
Introduction: Disturbance of neural circuits and chronic stress contribute to depression onset. Given the crucial role of paraventricular nucleus of thalamus (PVT) in emotional behaviors, however, the specific neural and ...
Pleiotropic role of CCR9/CCL25 signaling in adriamycin-induced cardiomyopathy [0.03%]
趋化因子受体CCR9/CCL25信号通路在阿霉素诱导的心肌病变中的多效性作用研究
Xue Wu,Zheng Wang,Zhenxing Liang et al.
Xue Wu et al.
Introduction: Adriamycin (ADR)-induced cardiomyopathy is a common problem in many cancer survivors. Recently, specific chemokine receptors have garnered interest as therapeutic targets in cardiovascular diseases. ...
Yibo Zhang,Yizhang Wu,Yong Wang et al.
Yibo Zhang et al.
Introduction: Achilles tendinopathy (AT) is a prevalent musculoskeletal disorder closely linked to oxidative stress. Existing evidence suggests a potential link between circadian clock rhythms and oxidative stress. Howeve...
Intra species dissection of phytophthora capsici resistance in black pepper [0.03%]
天竺葵中Phytophthora capsici抗性的种内分析
Yupeng Hao,Rui Fan,Yongyan Zhao et al.
Yupeng Hao et al.
Introduction: Black pepper, a financially significant tropical crop, assumes a pivotal role in global agriculture for the major source of specie flavor. Nonetheless, the growth and productivity of black pepper face severe...
The gut microbiotas with metabolites regulate the protective role of miR-30a-5p in myocardial infarction [0.03%]
肠道微生物及其代谢产物通过调节miR-30a-5p的表达发挥心肌梗死保护作用
Ruiying Wang,Ruo-Lan Chen,Chan Wu et al.
Ruiying Wang et al.
Introduction: Gut microbial homeostasis is closely associated with myocardial infarction (MI). However, little is known about how gut microbiota influences miRNAs-regulated MI. ...
Panaxatriol exerts anti-senescence effects and alleviates osteoarthritis and cartilage repair fibrosis by targeting UFL1 [0.03%]
.panaxatriol通过靶向UFL1发挥抗衰老作用并缓解骨关节炎和软骨修复纤维化
Biao Kuang,Nana Geng,Miao Yi et al.
Biao Kuang et al.
Introduction: Osteoarthritis (OA), the most common degenerative joint disease, can eventually lead to disability. However, no safe or effective intervention is currently available. Therefore, there is an urgent need to de...