Skin cancer segmentation and recognition from dermoscopy images: a novel framework based on improved DeepLabV3+ and network-level fused deep architectures [0.03%]
基于改进的DeepLabV3+和网络级深度融合架构的皮肤镜图像皮肤癌分割与识别框架
Mehak Arshad,Muhammad Attique Khan,Juan Manuel Górriz et al.
Mehak Arshad et al.
Introduction: Skin lesion segmentation and classification is an active research area in medical imaging for the large number of reported deaths in the recent years. Early diagnosis of skin cancer is essential to decrease ...
NLRP6 governs hippocampal microglial phagocytosis to resist stress-induced depressive-like behaviors in mice and the intervention effect of bezafibrate [0.03%]
NLRP6通过调控小胶质细胞吞噬作用抵抗应激诱导的抑郁样行为及贝扎普利酯的干预效应
Fan Yang,Xiuqin Kong,Yuefeng Hu et al.
Fan Yang et al.
Introduction: Microglial phagocytosis is crucial for maintaining central nervous system (CNS) homeostasis and is implicated in the development of depression. NOD-like receptor family pyrin domain containing 6 (NLRP6) repr...
Spatial-temporal lipidomics reveals dysregulated lipid metabolism in mouse brain during Alzheimer's disease progression [0.03%]
时空脂质组学揭示阿尔茨海默病小鼠脑中脂质代谢失调
Hongli Li,Zhihao Zhao,Lemei Zhu et al.
Hongli Li et al.
Introduction: Tracking spatial lipidomic changes during Alzheimer's disease (AD) progression is crucial for elucidating the underlying mechanisms of the disease. ...
Exploration and analysis of methylglyoxal-driven chronic inflammation in polycystic ovary syndrome [0.03%]
丙酮酸二甲基醛驱动的多囊卵巢综合征慢性炎症的探索和分析
Jiahui Song,Xiao Wang,Di Feng et al.
Jiahui Song et al.
Introduction: Chronic low-grade inflammation drives polycystic ovary syndrome (PCOS)-related metabolic disorders, but the underlying mechanisms remain unclear. Methylglyoxal, a key ovarian metabolite, promotes inflammatio...
Pressurized intraperitoneal cold atmospheric plasma as a novel therapeutic strategy for peritoneal metastatic carcinoma [0.03%]
腹腔转移性癌的一种新型治疗方法：冷等离子体疗法
Tianhao Min,Bo Zhang,Kaijie Ren et al.
Tianhao Min et al.
Introduction: Peritoneal metastatic carcinoma (PMC) faces limited therapeutic efficacy due to the peritoneal-plasma barrier and heterogeneous drug distribution. Current standard therapy (cytoreductive surgery combined wit...
Qihang Fang,Gan Li,Pei Liu et al.
Qihang Fang et al.
Background: Musculoskeletal diseases (MSDs) are prevalent health problems that have a chronic course and are closely related to metabolic disorders. Several incretins, including glucose-dependent insulinotropic polypeptid...
Computational glycosyltransferases masked deoxynivalenol toxicity and halted FHB spread in wheat grains [0.03%]
计算糖基转移酶可使小麦种子 masking 黄曲霉素毒性并停止 Fusarium 头部斑点病的传播
Ye Tian,Dachuan Zhang,Huadong Xing et al.
Ye Tian et al.
Introduction: Contamination of cereal grains by deoxynivalenol (DON) poses a significant threat to food safety. This toxic secondary metabolite, produced by F. graminearum, acts as a virulent factor to promote mycelium sp...
Field-parallel six-sample microfluidic detection of plant viruses via raffinose-assisted one-pot LAMP-CRISPR/Cas12b [0.03%]
基于膜诱导的微流控芯片植物病毒LAMP-CRISPR检测技术
Jiahui Wang,Wenqing Yang,Jingjing Fang et al.
Jiahui Wang et al.
Introduction: Plant viral diseases threaten food security globally. Rapid, accurate and early detection of viral pathogens is critical for proactive surveillance and effective control. ...
HDAC2 enhances the antimicrobial activity of neutrophils by promoting the formation of neutrophil extracellular traps (NETs) in sepsis [0.03%]
组蛋白去乙酰化酶2通过促进脓毒症中性粒细胞胞外陷阱的形成增强其抗菌活性
Zhan Li,Wang Hu,Kaiyan Lv et al.
Zhan Li et al.
Introduction: Sepsis is characterized as a life-threatening organ dysfunction resulting from a dysregulated host response to infection, representing a critical clinical syndrome. Uncontrolled infection and inflammation ar...
Synthetic microbial communities rescues strawberry from soil-borne disease by enhancing soil functional microbial abundance and multifunctionality [0.03%]
合成微生物组增强土壤功能菌丰度和多功能性从而拯救感染土传病害的草莓植株
Guoshen Lei,Zhixiang Han,Xingyue Wang et al.
Guoshen Lei et al.
Introduction: Synthetic microbial communities (SynCom) contribute to mitigating soil-borne crop diseases while enhancing both crop quality and yield. However, relatively little research has been done on the intricate regu...