Interfacial work function matching enables efficient hydrogen spillover for superior alkaline hydrogen evolution [0.03%]
界面功函匹配促进高效氢溢流从而提升碱性条件下析氢反应性能
Zhe Sun,Xiaodong Chen,Yitong Yin et al.
Zhe Sun et al.
Introduction: The sluggish kinetics of alkaline hydrogen evolution reaction (HER) governed by the consecutive steps of water adsorption/dissociation and hydrogen desorption remains a major obstacle to efficient green hydr...
Genetic characterization of non-typhoidal Salmonella strains and invasive traits associated with bloodstream infections in China (2017-2022) [0.03%]
中国非伤寒沙门氏菌的基因特征及与血流感染相关的侵袭性表型（2017-2022）
Kaichao Chen,Qiaoling Sun,Miaomiao Xie et al.
Kaichao Chen et al.
Introduction: Non-typhoidal Salmonella (NTS) is a significant bacterial pathogen causing foodborne diseases, with the potential for severe bloodstream infections (BSI) leading to complications such as sepsis and high mort...
Genome-wide association and functional studies reveal the genetic basis of salt tolerance in naked barley [0.03%]
全基因组关联和功能研究揭示裸大麦耐盐遗传基础
Jakkrit Sreesaeng,Cheng-Wei Qiu,Shou-Heng Shi et al.
Jakkrit Sreesaeng et al.
Introduction: Developing salt-tolerant crops requires the identification of key genetic factors and regulatory networks to mitigate the threat of soil salinization to global food security. ...
Multi-omics landscape and machine learning predictors of acute and chronic coronary syndrome diagnosis in young patients [0.03%]
年轻患者的急性冠脉综合征和慢性冠脉综合征的多组学图谱及机器学习诊断模型
Jianlong Yan,Nana Jin,Cong Xu et al.
Jianlong Yan et al.
Background: Acute coronary syndrome (ACS) is a leading global cause of death, and its incidence is increasingly rising in young adults, who exhibit distinct clinical characteristics from elderly patients. However, multi-o...
Achieving stable blue coloration of anthocyanins through pH-Modulated protein complexation [0.03%]
通过pH调节的蛋白质复合作用实现稳定蓝色花色苷染料
Wenxin Wang,Susana Soares,João T S Coimbra et al.
Wenxin Wang et al.
Introduction: Natural blue colorants are exceptionally scarce, and achieving stable blue hues from anthocyanins typically requires structural features such as extensive acylation or metal complexation, which limits their ...
Development of 3-carboxypropyl-grafted bio-inorganic lamellar nanocomposite as a new oral delivery platform for therapeutic peptides [0.03%]
开发具有3-羧基丙基接枝的生物无机层状纳米复合材料作为治疗肽的新口服传递平台
Jiwon Park,Gyu Lin Kim,Sang Hoon Lee et al.
Jiwon Park et al.
Introduction: One of the primary challenges in developing peptide drugs lies in their low permeability and inherent instability. Therefore, formulations that stabilize peptides and enhance the membrane transport are cruci...
4-Octyl itaconate-induced Nrf2 nuclear translocation mitigates Caspase-11-dependent noncanonical macrophage pyroptosis and acute lung injury [0.03%]
辛酰衣康酸诱导Nrf2核转位缓解非经典依赖的Caspase-11小胶质细胞pyroptosis和急性肺损伤
Tingyu Wen,Jindian Shi,Minkang Guo et al.
Tingyu Wen et al.
Introduction: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are severe inflammatory conditions, with mortality rates reaching 40%. A key driver of their pathogenesis is macrophage pyroptosis, whic...
Aloe-emodin alleviates osteoarthritis and maintains cytoskeletal homeostasis via targeting Septin7 ubiquitination [0.03%]
大黄素通过靶向Septin7泛素化来缓解骨关节炎和维持细胞骨架稳态
Peifeng Li,Zhen Chen,Zijian Zhang et al.
Peifeng Li et al.
Introduction: Osteoarthritis (OA) is the leading cause of disability worldwide. Due to its complex pathogenesis, no disease-modifying therapies currently exist to halt its progression. Consequently, there is an urgent cli...
Renal tubular Nfe2l1 protect cisplatin-induced acute kidney injury via suppressing ACSL4-dependent ferroptosis [0.03%]
肾小管Nrf1通过抑制ACSL4依赖性铁死亡来保护顺铂诱导的急性肾脏损伤
Jianqiang Hu,Yuewei Zhang,Yan Zhang et al.
Jianqiang Hu et al.
Introduction: Nfe2l1 is a transcription factor that is highly conserved and is encoded by the Nuclear Factor Erythroid 2 Like 1 (Nfe2l1) gene, which responds to oxidative stress, proteotoxic stress, and endoplasmic reticu...
Microplastics induce osteoarthritis by modulating chondrocyte inflammation and disrupting TGF-β signaling in mesenchymal stem cells [0.03%]
微塑料通过调节软骨细胞炎症并干扰间充质干细胞中TGF-β信号传导来诱导骨关节炎
Kainong Sun,Shuting Zhou,Meng Yang et al.
Kainong Sun et al.
Introduction: Microplastics (MPs) are pervasive pollutants that can accumulate in the human body through the food chain. Osteoarthritis (OA) is the most common degenerative joint disease with an increasing prevalence due ...