A novel link between enhanced chenodeoxycholic acid synthesis and multi-walled carbon nanotubes-induced proliferation inhibition and apoptosis in human ocular cells [0.03%]
一种关于增强鹅去氧胆酸合成与多壁碳纳米管诱导的人眼细胞增殖抑制和凋亡之间的新联系的研究
Yunxia Liang,Yang Zhou,Dongli Xie et al.
Yunxia Liang et al.
Introduction: The increasing amount of multi-walled carbon nanotubes (MWCNTs) released into the environment due to extensive production and application has raised great concerns for public health. However, there is scarce...
Integrative computational-experimental discovery of α-hederin as a multi-mechanistic, low-toxicity antifungal agent targeting Candida albicans CYP51 [0.03%]
计算与实验整合发现α- Hederin可作为针对白色念珠菌CYP51的多靶点低毒抗真菌剂
Xuan Wang,Yuchun Zhang,Gansukh Sunderiya et al.
Xuan Wang et al.
Introduction: Infections caused by pathogenic fungi such as Candida albicans have led to a continuous increase in disease morbidity and mortality, underscoring the urgent need for safer and more effective antifungal thera...
BMP4 cocktail promotes utricular progenitor reprogramming and vestibular functional recovery in adult mice [0.03%]
BMP4混合物促进成年小鼠耳石腺前体细胞重编程和前庭功能恢复
Dan You,Yunzhong Zhang,Kunkun Wang et al.
Dan You et al.
Introduction: Vestibular hair cells (HCs) are essential for maintaining balance and detecting head movements. In mammals, following vestibular damage HC regeneration derives from epithelial non-hair cells (ENHCs), which p...
Identification of marginal zone B cells cells in head and neck cancer with immunomodulatory characteristics [0.03%]
具有免疫调节特征的头颈部癌症边缘区B细胞的鉴定
Jiantong Bao,Jochen Hess,Annika C Betzler et al.
Jiantong Bao et al.
Introduction: Recently we observed high numbers of marginal zone B cells (MZBs) within murine head and neck squamous cell carcinoma (HNSCC) with immunosuppressive potential. To date, MZBs have not been linked to tumor dev...
Macrophage-induced immunomodulation in oral tissue repair and regeneration: Recent advances and future perspectives [0.03%]
口腔组织修复与再生中巨噬细胞介导的免疫调节：最新进展和未来展望
Yujie Wang,Jing Mao,Yifan Wang et al.
Yujie Wang et al.
Objectives: Maintaining immune balance plays crucial roles in the development and prognosis of injured oral tissues. Serving as critical components of immune system, macrophages are essential in accelerating oral tissue r...
Development and validation of an interpretable Machine learning model using routine laboratory biomarkers to Stratify severe pneumonia risk in young children [0.03%]
基于常规实验室生物标志物的机器学习模型的发展与验证：用于分层儿童肺炎严重风险
Wei Cui,Xinlv Zhang,Yang Chen et al.
Wei Cui et al.
Introduction: Severe pneumonia is a leading infectious cause of mortality in children under 5 years globally. Early identification of high-risk cases remains challenging due to the lack of reliable stratification tools. ...
Xue Yao,Xinjie Liu,Wenbin Cai et al.
Xue Yao et al.
Background: Spinal cord injury (SCI) initiates a cascade of secondary pathological processes significantly impairs functional recovery and leads to complications such as neuropathic pain. Arachidonic acid (AA) and its met...
Retraction notice to "Estrogen prevent atherosclerosis by attenuating endothelial cell pyroptosis via activation of estrogen receptor α-mediated autophagy." [J. Adv. Res. 28 (2021) 149-164] [0.03%]
撤稿通知“雌激素通过激活雌激素受体α介导的自噬来防止动脉粥样硬化发生的原因是雌激素可减轻内皮细胞焦亡现象。[J. Adv. Res. 28 (2021) 149-164]"
Qinghai Meng,Yu Li,Tingting Ji et al.
Qinghai Meng et al.
Urinary Cell-Free DNA detection platform for bacterial cystitis diagnosis via spot-based machine learning [0.03%]
基于尿液细胞游离DNA的机器学习点状检测平台用于细菌性膀胱炎诊断
Yan Liu,Kai Xiao,Ziping Wu et al.
Yan Liu et al.
Introduction: Bacterial cystitis is a prevalent infectious condition that is primarily caused by uropathogenic Escherichia coli (E. coli). The rapid and precise identification of this pathogen is crucial for guiding timel...
Selenoprotein H targets MTCH2 to regulate MFN2-dependent mitochondrial quality control to alleviate acute kidney injury [0.03%]
硒蛋白H通过靶向MTCH2调节MFN2依赖的线粒体质量控制来缓解急性肾损伤
Dongliu Luo,Yaning Qiu,Jiahong Chu et al.
Dongliu Luo et al.
Introduction: Mitochondrial dysfunction is recognized as a pivotal event in the pathogenesis of acute kidney injury (AKI). Selenoprotein (SelH), a mammalian selenoprotein, is extensively involved in regulating of diseases...