EVA1A responds to endoplasmic reticulum stress to regulate renal fibrosis by promoting TGF-β signaling pathway [0.03%]
EVA1A通过促进TGF-β信号通路响应内质网压力调节肾纤维化
Qiongdan Gao,Zhenkun Wang,Yuting Fu et al.
Qiongdan Gao et al.
Introduction: Renal fibrosis is a common pathological hallmark of chronic kidney disease (CKD), and ultimately leads to end-stage renal disease. ER-stress and TGF-β signaling pathway activation play critical roles in ren...
Regenerated lignocellulosic material from pea, bean, and artichoke waste as feedstock for bioplastic production [0.03%]
基于豌豆、大豆和洋蓟废弃物的再生木质纤维素材料作为生物塑料生产的原料
Cyrine Amara,Safa Baraketi,Yosr Barchouchi et al.
Cyrine Amara et al.
Introduction: Vegetable processing generates large quantities of lignocellulosic waste that are often underutilized. Developing bioactive, biodegradable packaging materials from such residues aligns with circular bioecono...
Microplastics and nanoplastics in follicular fluid are associated with diminished ovarian reserve: clinical and molecular insights [0.03%]
微塑料和纳米塑料与卵巢储备减少的相关性：临床及分子机制的见解
Manfei Si,Xianglei Xiong,Chuyu Yun et al.
Manfei Si et al.
Introduction: Ovarian aging is a significant concern, yet the influencing factors remain unclear. Environmental factors are crucial determinants of diminished ovarian reserve (DOR). Microplastics and nanoplastics (MNPs) a...
Longitudinal dynamics in frailty and incident all-cause dementia: a multicohort study [0.03%]
一项多队列研究：脆弱性纵向动态与全因痴呆症发病之间的关系
Yihong Ding,Zhaoping Wang,Jiabei He et al.
Yihong Ding et al.
Introduction: Frailty changes over time, but how these changes relate to the risk of dementia remains uncertain. Objective: To explore ...
Residential greenness, air pollution, and epilepsy: Insight in genetic susceptibility and life expectancy [0.03%]
绿地、空气污染与癫痫：遗传易感性和预期寿命的新见解
Feipeng Cui,Mengfan Wang,Linxi Tang et al.
Feipeng Cui et al.
Introduction: Epilepsy is one of the most common neurological disorders worldwide, yet evidence on its environmental determinants remains limited. Although a few studies have linked air pollution to epilepsy onset, the po...
METTL3 promotes neutrophil extracellular trap formation via SYK/ERK/MEK signaling during acute lung injury [0.03%]
METTL3通过SYK/ERK/MEK信号促进急性肺损伤过程中的中性粒细胞胞外陷阱形成
Shuhua Luo,Qianqian Zhang,Wending Zhou et al.
Shuhua Luo et al.
Introduction: Acute lung injury (ALI) is a life-threatening condition characterized by overwhelming pulmonary inflammation and neutrophil infiltration. Neutrophils play a central role in ALI pathogenesis by releasing prot...
Boosting luteolin bioavailability via P-glycoprotein efflux inhibition: a self-microemulsifying drug delivery systems [0.03%]
通过P-糖蛋白外排抑制增强大豆素的口服生物利用度：自微乳化药物传递系统的研究
Yimei Zheng,Boyu Chen,Xuanxiang Huang et al.
Yimei Zheng et al.
Introduction: The poor bioavailability of luteolin, a potent flavonoid with antioxidant and anti-inflammatory properties, hinders its therapeutic potential. The primary barriers to its absorption are its low solubility an...
Next-generation diabetes diagnostics: spectrochemical staging of red blood cells using vibrational spectroscopy [0.03%]
下一代糖尿病诊断技术：采用振动光谱法对红细胞进行光谱化学分型
Aleksandra Wilk,Natalia Wilkosz,Marzena Rugiel et al.
Aleksandra Wilk et al.
Introduction: Type 2 diabetes mellitus (T2DM) induces progressive biochemical and morphological alterations in red blood cells (RBCs), driven by hyperglycemia-induced oxidative stress and disrupted lipid-protein homeostas...
The alternative androgen receptor isoform a mitigates toxicity of polyglutamine-elongated mutant androgen receptor in spinal and bulbar muscular atrophy [0.03%]
含多聚谷氨酰胺延长突变雄激素受体的脊髓和球麻痹中，雄激素受体备选剪接变异a亚型可缓解其毒性作用
Marta Chierichetti,Roberta Andreotti,Barbara Tedesco et al.
Marta Chierichetti et al.
Introduction: Spinal and bulbar muscular atrophy (SBMA) is an X-linked neuromuscular disease caused by a CAG-repeat expansion in the androgen receptor (AR) gene,translated into an elongated polyglutamine (polyQ) tract in ...
MetsObesity: a novel classification system for predicting 15-year cardiovascular risk in the UK Biobank population [0.03%]
MetsObesity：一种新的分类系统，用于预测英国生物银行人群的15年心血管风险
Junaid Iqbal,Hui-Xuan Wu,Yan-Xuan Wu et al.
Junaid Iqbal et al.
Background: Obesity phenotyping often fails to capture the heterogeneity in cardiovascular risk. Current approaches rely heavily on BMI or conventional metabolic syndrome criteria, which underestimate cardiometabolic risk...