Association of hematopoietic loss of Y chromosome with valvular heart disease incidence and sex susceptibility [0.03%]
染色体Y丢失与瓣膜性心脏疾病发病率及性别易感性的关联性研究
Chenxuan Zhao,Yuanfeng Huang,Tianqi Ma et al.
Chenxuan Zhao et al.
Introduction: Hematopoietic mosaic Loss Of Y chromosome (LOY), a condition referring to the age-related loss of Y chromosome in a subset of blood cells, is associated with shortened life expectancy and increased risk of a...
Voxtalisib inhibits enterovirus 71 replication by downregulating host RAN and restoring IFN-STAT signaling [0.03%]
voxtalisib通过下调宿主RAN蛋白并恢复IFN-Stat信号转导抑制肠道病毒71型复制
Wang Delong,Yang Qingyu,Zhu Guangyan et al.
Wang Delong et al.
Introduction: Hand, foot, and mouth disease (HFMD) is a common enterovirus-induced illness primarily affecting children under 5 years of age. Enterovirus 71 (EV71) is a major causative agent associated with severe HFMD th...
Corrigendum to "An updated review and recent advancements in carbon-based bioactive coatings for dental implant applications" [J. Adv. Res. 72 (2025) 265-286] [0.03%]
关于“碳基生物活性涂层在牙科植入物应用中的最新进展和更新综述”的勘误修正[J. Adv. Res. 72 (2025) 265-286]
Nazrah Maher,Anum Mahmood,Muhammad Amber Fareed et al.
Nazrah Maher et al.
A cocktail hydrogel promoting the functional interneurons regeneration of human neural progenitor cells for brain injury therapy [0.03%]
一种促进人类神经干细脑损伤治疗的功能中间神经元再生的鸡尾酒水凝胶
Di Zhang,Jun Chen,Huaisong Lin et al.
Di Zhang et al.
Introduction: Traumatic Brain Injury (TBI) usually leads to substantial mortality and disability among adult populations. Neural progenitor cells (NPCs) transplantation exhibits great potential in TBI treatment. However, ...
Squalene epoxidase promotes paraquat-induced pulmonary toxicity through endoplasmic reticulum-mediated ferroptosis [0.03%]
角鲨烯环氧酶通过内质网介导的铁死亡促进百草枯诱导的肺毒性
Yanyan Zhu,Wenwen Zhao,Wan Li et al.
Yanyan Zhu et al.
Introduction: Paraquat (PQ), a widely used herbicide, causes lethal lung injury through unresolved mechanisms, posing urgent clinical challenges due to the lack of effective antidotes. ...
Cadmium targeting MLKL-Drp1 axis to trigger mitochondrial oxidative stress contributes to necroinflammation in rat kidney [0.03%]
镉通过靶向MLKL-Drp1轴触发线粒体氧化应激参与大鼠肾脏坏死性炎症
Cai-Yu Lian,Wei-Hao Xia,Ming Cheng Sun et al.
Cai-Yu Lian et al.
Introduction: Acute kidney injury (AKI) induced by cadmium (Cd) manifests excessive inflammation with no effective therapy. Necroptosis, a novel manner of necrosis that regulates cell death, has been revealed important fu...
Antiviral activity and mechanism of purine morpholine nucleoside analogues incorporating a sulfonamide fragment [0.03%]
含磺酰胺片段的嘌呤吗啉核苷类似物的抗病毒活性及作用机制研究
Yuyuan Yang,Runjiang Song,Shaobo Wang et al.
Yuyuan Yang et al.
Introduction: Pepper mild mottle virus (PMMoV) poses an enormous threat to pepper production because of its high infectivity and soil persistence. Commercially available antiviral agents, ningnanmycin and ribavirin, have ...
Single-cell and spatial transcriptome profiling identifies cellular heterogeneity and immunosuppressive tumor microenvironment in inflammatory breast cancer [0.03%]
单细胞及空间转录组分析揭示炎性乳腺癌的异质性和免疫抑制微环境
Xueni Sun,Jing Xia,Haiyang Jiang et al.
Xueni Sun et al.
Introduction: Inflammatory breast cancer (IBC) is a highly aggressive subtype of breast cancer associated with a poor prognosis. A better understanding of IBC's pathological and molecular basis is crucial for developing p...
Enhancement of NK cell activity via DNA-sensing inhibition by Poxin transgene [0.03%]
通过正痘病毒基因Poxin抑制DNA感知来增强NK细胞活性
Ling-Zu Kong,Seok-Min Kim,Soo Yun Lee et al.
Ling-Zu Kong et al.
Introduction: Natural Killer (NK) cell therapy has shown strong potential for cancer treatment; however, NK cell efficacy is limited by their short lifespan and suppression within the tumor microenvironment. One factor co...
Nano-priming with selenium nanoparticles reprograms seed germination, antioxidant defense, and phenylpropanoid metabolism to enhance Fusarium graminearum resistance in maize seedlings [0.03%]
硒纳米颗粒介导的种子纳米启动子重编程谷物发芽、抗氧化防御和苯丙烷代谢以提高玉蜀黍属植物幼苗的抗病性
Qinyong Dong,Tingjie Huang,Chunran Zhou et al.
Qinyong Dong et al.
Introduction: Fusarium graminearum (F. graminearum) threatens maize through stem rot and deoxynivalenol (DON) contamination. Conventional approaches like chemical seed coatings are constrained by limited long-term efficac...