scMapNet: Marker-based cell type annotation of scRNA-seq data via vision transfer learning with tabular-to-image transformations [0.03%]
基于视觉迁移学习的单细胞类型标记注释方法scMapNetBar chart
Zhe Yu,Ying Ye,Jianbo Pan
Zhe Yu
Introduction: Identifying cell types is a key step in single-cell RNA sequencing data analysis that aids in understanding cellular heterogeneity and facilitates downstream analyses such as those concerning cell-cell inter...
Development of a selectively AURKB targeting peptide degradation drug with artificial intelligence-assisted design for the treatment of acute lymphoblastic leukemia [0.03%]
人工智能辅助设计选择性靶向AURKB的肽降解剂治疗急性淋巴细胞白血病
Yun Xie,Hui Feng,Yinong Huang et al.
Yun Xie et al.
Introduction: Acute lymphoblastic leukemia (ALL) is a highly heterogeneous hematologic malignancy with poor prognosis in refractory and relapsed cases. Aurora kinase B (AURKB), a member of the Aurora kinase family, is mar...
Supra-Carbon dots for methyl-paraoxon detection using a new controllable IFE-based method [0.03%]
基于IFE的一种新的可控制检测方法用于甲基对氧磷的检测研究
Mai Luo,Jihai Cai,Sijia Pu et al.
Mai Luo et al.
Introduction: Pesticide residues pose a significant threat to human health. Inner filter effect (IFE) stands out for its ability to enable the rapid and cost-effective establishment of fluorescent detection systems. Never...
Never underestimate honeybees: Their exceptionally diverse adaptive strategies [0.03%]
千万不要低估蜜蜂：它们有特别多样化的适应策略
Guilin Li,Shuwei Wang,Liu Wang et al.
Guilin Li et al.
Background: As major pollinators in terrestrial ecosystems, honeybees are highly sensitive to environmental changes. To survive, they have evolved diverse adaptive strategies to cope with complex and fluctuating condition...
Advanced immunodiagnostics for periodontal disease: Targeted detection of Kgp and RgpB using A7 and G1 antibody set [0.03%]
牙周病免疫诊断技术新进展——运用A7和G1抗体对Kgp及RgpB的特异性检测
Hyeran Kim,Kyeonghye Guk,Soyeon Yi et al.
Hyeran Kim et al.
Introduction: Periodontal disease, primarily caused by Porphyromonas gingivalis, leads to chronic inflammation and eventual tooth loss, with systemic health implications. Current diagnostic methods rely on clinical assess...
Matrix stiffness drives squamous cell carcinoma progression via a Piezo1-mediated mechanotransduction feedback loop [0.03%]
基质硬度通过Piezo1介导的机械转导反馈回路驱动鳞状细胞癌进展
Zixi Jiang,Yantao Xu,Ying Wang et al.
Zixi Jiang et al.
Introduction: Squamous cell carcinoma (SCC) is one of the most frequent solid tumor accounting for more than one million cancer deaths annually. Emerging evidence highlights the critical role of mechanical signaling in tu...
Long non-coding RNA antisense of insulin-like growth factor 2 receptor promotes osteogenic differentiation by enhancing runt-related transcription factor 2 translation: A potential therapeutic target for osteoporosis [0.03%]
长链非编码RNAIGF2RP通过增强RUNX2翻译促进成骨分化：一种潜在的抗骨质疏松症治疗靶点
Jing Zhu,Sicong Zhao,Xiaoxiu Li et al.
Jing Zhu et al.
Introduction: Osteoporosis is a chronic metabolic disorder characterized by progressive bone loss and increased susceptibility to fractures, for which there is currently no curative treatment that can fully reverse or eli...
Physiological and multi-omics insights into ultraviolet B-induced stress adaptation in Fritillaria cirrhosa native to the Qinghai-Tibet Plateau [0.03%]
紫外光B辐射诱导下的青海省乌头属植物适应机制的生理及多组学研究洞察
Zemin Yang,Dan Gao,Ye Wang et al.
Zemin Yang et al.
Introduction: Fritillaria cirrhosa (Liliaceae), an endangered medicinal plant of the Qinghai-Tibet Plateau, exhibits strong adaptability to ultraviolet B (UV-B) radiation during the transition from wild to artificial habi...
SOD1 regulates CXCR4 transcription in cortical neurons for establishment of cerebral ischemic tolerance [0.03%]
SOD1调节皮质神经元中的CXCR4转录以建立脑缺血耐受性
Ming-Xi Li,Guangpu Su,Ying Zhou et al.
Ming-Xi Li et al.
Introduction: Understanding of cerebral ischemic tolerance could provide important insight into viable neuroprotective strategies against ischemic stroke. ...
Artificial intelligence-driven precision treatment of reproductive medicine-related diseases: the optimal protocol choice for IVF-ET [0.03%]
人工智能驱动的生殖医学相关疾病精准治疗：试管婴儿的最佳方案选择
Li Wen,Di Wu,Jinhan Ruan et al.
Li Wen et al.
Introduction: Optimal OS selection is critical for IVF success, but expert-based decisions often lack consistency in outcomes, cost-efficiency, and personalization, highlighting the need for more individualized and data-d...