The Power of Exercise: Unlocking the biological Mysteries of Peripheral-Central crosstalk in Parkinson's disease [0.03%]
运动的力量：揭示帕金森病周围-中枢交叉沟通的生物奥秘
Jingwen Li,Tingting Liu,Meiyan Xian et al.
Jingwen Li et al.
Background: Exercise is a widely recognized non-pharmacological treatment for Parkinson's Disease (PD). The bidirectional regulation between the brain and peripheral organs has emerged as a promising area of research, wit...
Nutrient supplementation mitigates retinal dysfunction in Acox1 knockout mice with impaired peroxisomal fatty acid oxidation [0.03%]
ACOX1敲除小鼠视网膜功能障碍揭示过氧化物酶体脂肪酸氧化障碍导致的视网膜营养不良及其补充治疗前景
Myriam Boeck,Hitomi Yagi,Chuck T Chen et al.
Myriam Boeck et al.
Introduction: Dyslipidemia contributes to many retinal diseases, but underlying lipid processing pathways are not fully understood. Peroxisomes oxidize very long-chain fatty acids and generate docosahexaenoic acid (DHA). ...
Saccharide mapping apparatus for real-time PAGE detection of polysaccharides [0.03%]
用于实时检测多糖的PAGE蔗糖映射装置
Baojie Zhu,Jing Zhao,Shaoping Li
Baojie Zhu
Introduction: As a key technique in saccharide mapping, polysaccharides analysis using carbohydrate gel electrophoresis (PACE) analysis platform has always been self-assembled and built in various laboratories independent...
Cracking melanoma's armor: Supramolecular dual-strike on XPO1 and β-catenin to overcome resistance [0.03%]
cracking melanoma's armor: Supramolecular dual-strike on XPO1 and β-catenin to overcome resistance：击破黑色素瘤的盔甲：通过XPO1和β-连环蛋白的超分子双重攻击来克服耐药性
Yinliang Lu,Ruishan Guo,Wenfei Song et al.
Yinliang Lu et al.
Introduction: XPO1 plays a crucial role in the nuclear export machinery, making it an attractive target for inhibiting nuclear-cytoplasmic transport in melanoma, where its overexpression is linked to unfavorable prognosis...
Activation of Sirt6 by icariside Ⅱ alleviates depressive behaviors in mice with poststroke depression by modulating microbiota-gut-brain axis [0.03%]
黄酮类化合物icariside Ⅱ通过调节微生物-肠-脑轴激活Sirt6减轻中风后抑郁小鼠的抑郁行为
Jianmei Gao,Yifan He,Fuguo Shi et al.
Jianmei Gao et al.
Background: Sirt6-mediated gut microbiota plays a vital role in poststroke depression (PSD). Icariside Ⅱ (ICS Ⅱ) is a naturally-occurring neuroprotectant with Sirt6 induction potency. However, it is unknown whether ICS ...
The causal links between long-term exposure to major chemical components of PM2.5 and overall outpatient visits in mainland China: A nationwide study in the difference-in-differences framework [0.03%]
长期暴露于PM2.5主要化学成分与中国大陆总体门诊就诊之间的因果联系：差异中的差异框架下的全国性研究
Shuaiqi Zhang,Zhibing Chen,Zhicheng Du et al.
Shuaiqi Zhang et al.
Introduction: Although the adverse health effects of PM2.5 exposure has been well documented, evidence of its adverse effect on overall outpatient visits was still limited. Besides, the adverse health effects of PM2.5 exp...
Reinforcement learning-based generative artificial intelligence for novel pesticide design [0.03%]
基于强化学习的生成式人工智能在新型农药设计中的应用
Ruoqi Yang,Biao Li,Jin Dong et al.
Ruoqi Yang et al.
Introduction: Pesticides play a pivotal role in ensuring food security, and the development of green pesticides is an inevitable trend in global agricultural progress. Although deep learning-based generative models have r...
Factors affecting the intracytoplasmic sperm cell injection outcomes: A meta-analysis of porcine studies [0.03%]
影响胞浆内精子注射结果的因素：猪研究的meta分析
Muhammad Ameen Jamal,Ali Husnain,Kaixiang Xu et al.
Muhammad Ameen Jamal et al.
Background: Intracytoplasmic sperm cell injection (ICSI) has the potential to produce gene-edited (GE) pigs for biomedical research, but its success is limited. The factors impeding ICSI in pigs are impractical in-vivo oo...
Corrigendum to Exopolysaccharide from the yeast Papiliotrema terrestris PT22AV for skin wound healing [Journal of Advanced Research,Volume 46, April 2023, Pages 61-74] [0.03%]
关于酵母Papiliotrema terrestris PT22AV的外聚糖在皮肤伤口愈合中的应用[《高级研究杂志》，第46卷，2023年4月，第61-74页]的勘误表
Masoud Hamidi,Oseweuba Valentine Okoro,Giuseppe Ianiri et al.
Masoud Hamidi et al.
Dual function of MrgprB2 receptor-dependent neural immune axis in chronic pain [0.03%]
MrgprB2受体依赖性神经免疫轴在慢性疼痛中的双重功能
Yucui Jiang,Fan Ye,Jian Zhang et al.
Yucui Jiang et al.
Introduction: Neuro-immune interactions have been recognized to be involved in the development of neuropathic pain induced by chemotherapeutic drugs (CINP). However, its role in pain resolution remains largely unknown, pa...