GhLBD18 triggers GhATG18a-dependent autophagy during somatic embryogenesis in cotton [0.03%]
GhLBD18在棉花体细胞胚胎发生过程中触发依赖于GhATG18a的自噬作用
Jiachen Yuan,Xingxing Zhi,Xingxing Liu et al.
Jiachen Yuan et al.
Introduction: Autophagy is well established as a critical mechanism in plant stress responses and sexual reproduction, yet its molecular mechanisms during asexual reproduction remains poorly characterized. Deciphering the...
Sunlight to Plasma: Mimicking nature's light for smarter agriculture and crop production [0.03%]
从阳光到等离子体：模拟自然光以实现更智能的农业和作物生产
Pankaj Attri,Kenji Ishikawa,Kazunori Koga
Pankaj Attri
Background: Over Earth's history, the Sun has continuously released coronal mass ejections of plasma that have flowed toward Earth, generating the need for reactive oxygen and nitrogen species (RONS) for plants. On the ot...
How cotton-specialized aphids hack cucumber plants: DNA methylation reshapes zinc finger protein xFG20-1 regulation for adaptive trade-offs [0.03%]
棉蚜专化危害黄瓜的机制：DNA甲基化重塑锌指蛋白xFG20-1调控以适应颉顽困境
Xueke Gao,Hui Xue,Li Wang et al.
Xueke Gao et al.
Introduction: The cotton-specialized aphid biotype Hap1 cannot survive directly on cucumber but achieves adaptation after several generations via an intermediate zucchini host, epigenetic mechanisms likely mediate this ad...
Cytobiological and molecular mechanisms underlying hybridization fertility differences among albino tea cultivars (Camellia sinensis) [0.03%]
白化茶树品种(Camellia sinensis)杂交生育力差异的细胞生物学和分子机制研究
Xiaohan Xu,Chunju Peng,Anqi Xing et al.
Xiaohan Xu et al.
Camellia sinensis is a perennial economic crop, and albino cultivars ('Baiye No.1' (BY), 'Huangjinya' (HA), 'Huangjinye' (HE)) are valuable for hybrid breeding but exhibit distinct hybridization seed set rates. This study explored these dif...
Yaozhi Zhang,Junyang Huang,Yihang Li et al.
Yaozhi Zhang et al.
Background: Single-cell genetic perturbation screens are increasingly used to study gene function at single-cell resolution. However, their analysis remains difficult because available computational methods differ in assu...
Blood and brain tissue RNA transcriptomics reveal six potential targets of Parkinson's disease: a meta-analysis [0.03%]
血和脑组织RNA转录组揭示六种潜在的帕金森病靶点：一项荟萃分析
Suh Yee Goh,Bryan Wei De Theng,Helen Lisa Ong et al.
Suh Yee Goh et al.
Background: The multi-factorial Parkinson's disease (PD) remains an incurable disease to date. Significant efforts have gone into identifying PD targets through high-throughput screening technologies such as microarrays a...
The impact of stress on cancer immunotherapy: from mechanistic insights to intervention strategies [0.03%]
压力对癌症免疫治疗的影响：从机制见解到干预策略
Zhijie Wang,Jiali Yao,Yuanyuan Zhang et al.
Zhijie Wang et al.
Background: Immunotherapy has achieved significant breakthroughs in cancer treatment, but its clinical efficacy remains limited in many patients. Concurrently, epidemiological studies indicate that many cancer patients su...
N-myristoyltransferase-mediated protein myristoylation: molecular mechanisms, pathological roles, and targeted therapeutic strategies [0.03%]
N-myristoy转移酶介导的蛋白质肉豆蔻酰化：分子机制、病理作用和靶向治疗策略
Wenqing Liu,Zhe Chen,Zhen Huang et al.
Wenqing Liu et al.
Background: Protein N-myristoylation, catalyzed by N-myristoyltransferases (NMT1 and NMT2), is a critical lipid modification conferring membrane-binding and conformational plasticity to target proteins. Historically viewe...
HMT + mediated visual motion perception deficits in treatment-resistant depression: a neuroimaging, genomic and neurochemical perspective [0.03%]
难治性抑郁障碍的HMT介导的视运动感知缺陷：神经影像学、基因组和神经化学角度的观点
Shaoyong Ye,Tao Jin,Ruihan Wu et al.
Shaoyong Ye et al.
Background: Visual motion perception (VMP) deficit in depression is mediated by the human middle temporal complex (hMT+). However, the reorganization of neuroactivity-perception in treatment-resistant depression (TRD) and...
Transforming mRNA drug design with AI: From UTR and codon optimization to coordinated design [0.03%]
人工智能变革mRNA药物设计：从调控序列和密码子优化到整体设计
Yuqi Shi,Chuanlong Zeng,Xia Sheng et al.
Yuqi Shi et al.
Background: The design of mRNA drugs involves a complex and high-dimensional optimization of sequence elements to balance stability, translation efficiency, and immunogenicity. Traditional methods, often relying on local ...