Dynamic feature selection improves influenza forecasting accuracy and generalization across countries [0.03%]
动态特征选择可提高流感预测的准确性并在各国间进行预测模型泛化
Jingyi Liang,Zhiqi Zeng,Kai Liao et al.
Jingyi Liang et al.
Introduction: The differentiation in epidemic patterns and multiple influencing factors pose significant challenges to influenza forecasting, highlighting the need for novel methods to improve predictive accuracy and cros...
DNA methylation regulates asymmetric zygote sub-genome activation in wheat [0.03%]
DNA甲基化在小麦zygote时期异型激活的作用机制研究
Yunzhen Li,Chao He,Xue Li et al.
Yunzhen Li et al.
Introduction: Fertilization is an essential step in the life cycles of both animals and plants and gene transcription regulation during this process ensures its proper initiation. Chromatin remodeling, including DNA methy...
Rhein inhibits respiratory syncytial virus entry by stabilizing the prefusion conformation of the fusion protein [0.03%]
来酚通过稳定融合蛋白前聚合并抑制呼吸道合胞病毒的侵入
Kunhuan Yang,Yingcai Xiong,Junxi Song et al.
Kunhuan Yang et al.
Introduction: Respiratory syncytial virus (RSV) remains a major cause of severe lower respiratory tract infections. The high mutability of its RNA genome necessitates novel therapeutics, with the viral fusion (F) protein ...
Corrigendum to "A novel fuzzy system-based genetic algorithm for trajectory segment generation in urban global positioning system" [J. Adv. Res. 81 (2026) 469-480] [0.03%]
关于“一种基于模糊系统的遗传算法在城市全球定位系统轨迹段生成中的应用”的勘误(卷81,2026年,469-480页)
Xiaojuan Ran,Naret Suyaroj,Worawit Tepsan et al.
Xiaojuan Ran et al.
Bacterial terminal oxidase bo3 as a primary respiratory target of cathelicidin peptide hc-cath against Acinetobacter baumannii [0.03%]
宿主防御肽HC-CATH通过作用于鲍曼不动杆菌末端氧化酶BO3发挥抗菌效应
Yi Wang,Shengwen Zhou,Deyuan Su et al.
Yi Wang et al.
Introduction: Antimicrobial peptides (AMPs) hold promises to counter antimicrobial resistance. They cause several deleterious effects in bacterial cells by interfering with cell wall biosynthesis, DNA replication, transcr...
Rutin triggers IRE1-mediated GSDMD-dependent pyroptosis in macrophages to suppress systemic Salmonella infection [0.03%]
rutin通过激活IRE1介导的GSDMD依赖性焦亡抑制巨噬细胞中的系统性沙门氏菌感染
Zi-Jian Zheng,Yang Luo,Hai-Yi Zhang et al.
Zi-Jian Zheng et al.
Introduction: Rutin (RT), a flavonoid used clinically as a vasoprotective agent, exhibits anti-inflammatory and antioxidant activities. However, its immunomodulatory mechanisms, particularly during bacterial infection, re...
A Poaceae-specific DREB-A6 transcription factor TaDREB26-B regulates ABA responses and enhances drought stress tolerance in wheat [0.03%]
一种小麦特有转录因子TaDREB26-B调控ABA响应和干旱胁迫耐受性
Yufan Zhang,Min Tu,Jiapeng Han et al.
Yufan Zhang et al.
Introduction: Dehydration-responsive element-binding (DREB) transcription factors, members of the AP2/ERF superfamily, are pivotal regulators of stress-responsive gene expression by binding to DRE/CRT cis-elements. They r...
Lipeng Liao,Yuan Meng,Yuhang Shi et al.
Lipeng Liao et al.
Background: Organoids are moving from self-organized three-dimensional (3D) cultures toward engineered living systems with translational intent. Yet most platforms still rely on static, poorly defined matrices and limited...
Mitochondria orchestrated immune microenvironment and response in health and disease-clinically relevant outlook and recommendations [0.03%]
线粒体在健康和疾病中调控免疫微环境及反应的临床展望与建议
Kai Yang,Junlong Bi,Yu Cao et al.
Kai Yang et al.
Background: The homeostatic balance of the immune microenvironment is key to maintaining bodily health, and its disorder is closely related to the occurrence and development of various major diseases such as cardiovascula...
Spatiotemporal multiomics reveal a default CD4 fate and a stem-like CD8 T cell subset in the thymus [0.03%]
时空多组学揭示了胸腺中默认的CD4命运和类似干细胞的CD8 T细胞亚群
Hanpeng Luo,Xiuping Cui,Yaqin Li et al.
Hanpeng Luo et al.
Background: T cell development in the thymus proceeds through coordinated transcriptional and spatial transitions. While key stages have been described, the precise timing and regulatory logic of lineage bifurcation-such ...