Lekha Pandit
Lekha Pandit
Multiple Sclerosis (MS) is being diagnosed in increasing numbers in metropolitan cities of India for which the availability of specialist neurologists and magnetic resonance imaging (MRI) facilities are primarily responsible. Epidemiologica...
Multiple autoimmune propensity and B-non-hodgkin lymphoma: cause or effect? [0.03%]
多种自身免疫倾向与B-非霍奇金淋巴瘤：因果关系？
E Koumati,M Palassopoulou,P Matsouka et al.
E Koumati et al.
We report a case of multiple autoimmunity consisting of the presence of autoimmune haemolytic anaemia (AIHA), antimitochondrial antibodies (AMAs), and antiphospholipid antibodies (APLAbs) as the presenting manifestations of an extrahepatic ...
Case Reports
Autoimmune diseases. 2011:2011:841325. DOI:10.4061/2011/841325 2011
Antineutrophil cytoplasmic antibodies testing in a large cohort of unselected greek patients [0.03%]
希腊未经挑选的大批患者抗中性粒细胞胞浆抗体检测
Konstantinos Tsiveriotis,Alexandra Tsirogianni,Elena Pipi et al.
Konstantinos Tsiveriotis et al.
Objective. To retrospectively evaluate ANCA testing in a cohort of unselected Greek in- and outpatients. Methods. In 10803 consecutive serum samples, ANCA were tested by indirect immunofluorescence (IIF) and ELISA. ELISA in inpatients was p...
Daniel Smyk,Evangelos Cholongitas,Stephen Kriese et al.
Daniel Smyk et al.
Primary biliary cirrhosis (PBC) is a chronic immune-mediated cholestatic liver disease of unknown aetiology which affects mostly women in middle age. Familial PBC is when PBC affects more than one member of the same family, and data suggest...
Impaired deoxyribonuclease I activity in patients with inflammatory bowel diseases [0.03%]
炎症性肠病患者脱氧核糖核酸酶I活性受损
Karin Malíčková,Dana Duricová,Martin Bortlík et al.
Karin Malíčková et al.
Background and Aims. Deoxyribonuclease I (DNaseI) is an endonuclease that facilitates chromatin breakdown and promotes susceptibility to autoimmune disorders. The aim of current study was to investigate serum DNase I activity in patients wi...
E Lensch,W H Jost
E Lensch
Multiple sclerosis is an inflammatory disease leading to disseminated lesions of the central nervous system resulting in both somatomotor and autonomic disturbances. These involve the central centers of the autonomic nervous system, as well...
Lights and shadows of cyclophosphamide in the treatment of multiple sclerosis [0.03%]
环磷酰胺治疗多发性硬化症的利与弊
Francesco Patti,Salvatore Lo Fermo
Francesco Patti
Cyclophosphamide (cy) is an alkylating agent used to treat malignancies and immune-mediated inflammatory nonmalignant processes. It has been used as a treatment in cases of worsening multiple sclerosis (MS). Cy is currently used for patient...
Sreeram V Ramagopalan,David A Dyment
Sreeram V Ramagopalan
We review here our current understanding of the genetic aetiology of the common complex neurological disease multiple sclerosis (MS). The strongest genetic risk factor for MS is the major histocompatibility complex which was identified in t...
May diet and dietary supplements improve the wellness of multiple sclerosis patients? A molecular approach [0.03%]
饮食与膳食补充剂能改善多发性硬化患者的健康吗？一种分子方法的研究视角
Paolo Riccio,Rocco Rossano,Grazia Maria Liuzzi
Paolo Riccio
Multiple sclerosis is a complex and multifactorial neurological disease, and nutrition is one of the environmental factors possibly involved in its pathogenesis. At present, the role of nutrition is unclear, and MS therapy is not associated...
The caspase pathway as a possible therapeutic target in experimental pemphigus [0.03%]
实验性天疱疮中胱冬酶途径作为可能的治疗靶点
Deyanira Pacheco-Tovar,Argelia López-Luna,Rafael Herrera-Esparza et al.
Deyanira Pacheco-Tovar et al.
Apoptosis plays a role in pemphigus IgG-dependent acantholysis; theoretically, the blockade of the caspase pathway could prevent the blistering that is caused by pemphigus autoantibodies. Using this strategy, we attempted to block the patho...