Early onset multiple sclerosis has worse prognosis than adult onset multiple sclerosis based on cognition and magnetic resonance imaging [0.03%]
基于认知和磁共振成像的证据表明，儿童期起病的多发性硬化症预后更差
Serkan Ozakbas,Derya Kaya,Egemen Idiman
Serkan Ozakbas
Objectives. In the present study, we aimed to compare the childhood and adult onset multiple sclerosis patients prospectively in their adulthood on the basis of clinical and magnetic resonance imaging (MRI) findings and cognitive impairment...
Zdenka Ulcova-Gallova,Alice Mockova,Miroslava Cedikova
Zdenka Ulcova-Gallova
Female patients in reproductive age with systemic lupus erythematosus and fertility complications together are observed by rheumatologists, gynecologists, and reproductive immunologists. The paper notes the presence of autoantibodies to zon...
Evaluation of ENA-6 Profile by ELISA Immunoassay in Patients with Systemic Lupus Erythematodes [0.03%]
系统性红斑狼疮患者ENA-6谱系ELISA免疫检测分析评估
Izeta Aganovic-Musinovic,Jasenko Karamehic,Lamija Zecevic et al.
Izeta Aganovic-Musinovic et al.
Autoimmune diseases occur in 3-5% of the population. Study included 30 patients with clinically diagnosed SLE and 30 healthy controls (American college of Rheumatology, 1997). SLE was diagnosed according to criteria issued in 1997 by the Am...
Role of hsp90 in systemic lupus erythematosus and its clinical relevance [0.03%]
HSP90在系统性红斑狼疮中的作用及其临床意义
Hem D Shukla,Paula M Pitha
Hem D Shukla
Heat shock proteins (HSP) are a family of ubiquitous and phylogenically highly conserved proteins which play an essential role as molecular chaperones in protein folding and transport. Heat Shock Protein 90 (Hsp90) is not mandatory for the ...
Association of HLA-DQB1∗05:02 and DRB1∗16 Alleles with Late-Onset, Nonthymomatous, AChR-Ab-Positive Myasthenia Gravis [0.03%]
HLA-DQB1*05：02和DRB1*16等位基因与晚发性非胸腺瘤乙酰胆碱受体抗体阳性重症肌无力的关联研究
Manuela Testi,Chiara Terracciano,Annalisa Guagnano et al.
Manuela Testi et al.
An association of several HLA alleles with myasthenia gravis (MG) has been reported. Aim of this work was to analyze the HLA allele profile in a survey of 76 unselected Italian MG patients and in a subgroup characterized by disease onset af...
Abdul Latif Hamdan,Sahar Farhat,Rami Saadeh et al.
Abdul Latif Hamdan et al.
Objective. To investigate the voice-related quality of life in a group of patients with multiple sclerosis. Participants. A total of 87 subjects (59 MS subjects and 28 controls) participated in this study. Main Outcome Measures. Variables i...
Aberrant Activation of Heat Shock Protein 60/65 Reactive T Cells in Patients with Behcet's Disease [0.03%]
贝赫切特病患者热休克蛋白60/65反应T细胞的活化异常
Jun Shimizu,Tomoko Izumi,Noboru Suzuki
Jun Shimizu
Behcet's disease (BD) is a multisystemic inflammatory disease and is characterized by recurrent attacks on eyes, brain, skin, and gut. There is evidence that skewed T-cell responses contributed to its pathophysiology in patients with BD. We...
Scott E Wenderfer,Trisha Thacker
Scott E Wenderfer
The occurrence of nephritis in patients with systemic lupus erythematosus is associated with increased morbidity and mortality. The pathogenesis of lupus nephritis is complex, involving innate and adaptive cellular and humoral immune respon...
Stuart K Calderwood,Mary Ann Stevenson,Ayesha Murshid
Stuart K Calderwood
Heat shock proteins (HSPs) have been linked to the therapy of both cancer and inflammatory diseases, approaches that utilize contrasting immune properties of these proteins. It would appear that HSP family members Hsp60 and Hsp70, whether f...
H11/HspB8 and Its Herpes Simplex Virus Type 2 Homologue ICP10PK Share Functions That Regulate Cell Life/Death Decisions and Human Disease [0.03%]
H11/HspB8及其HSV-2同源蛋白ICP10PK共享调节细胞生死决定及人类疾病的功能
Laure Aurelian,Jennifer M Laing,Ki Seok Lee
Laure Aurelian
Small heat shock proteins (sHsp) also known as HspB are a large family of widely expressed proteins that contain a 90 residues domain known as α-crystallin. Here, we focus on the family member H11/HspB8 and its herpes simplex virus type 2 ...