Trypanosome prereplication machinery: a potential new target for an old problem [0.03%]
锥虫预复制机制：一个潜在的新靶点对抗旧问题
Simone Guedes Calderano,Patricia Diogo de Melo Godoy,Julia Pinheiro Chagas da Cunha et al.
Simone Guedes Calderano et al.
Approximately ten million people suffer from Chagas disease worldwide, caused by Trypanosoma cruzi, with the disease burden predominately focused in Latin America. Sleeping sickness is another serious health problem, caused by Trypanosoma b...
Erika C G Aguieiras,Cláudia O Veloso,Juliana V Bevilaqua et al.
Erika C G Aguieiras et al.
Estolides are vegetable-oil-based lubricants obtained from oleic acid or any source of hydroxy fatty acids. In this work, the estolides synthesis from oleic acid and methyl ricinoleate (biodiesel from castor oil), using immobilized commerci...
Andrew M Slupe,Ronald A Merrill,Stefan Strack
Andrew M Slupe
Protein phosphatase 2A- (PP2A-) catalyzed dephosphorylation of target substrate proteins is widespread and critical for cellular function. PP2A is predominantly found as a heterotrimeric complex of a catalytic subunit (C), a scaffolding sub...
Laccase: microbial sources, production, purification, and potential biotechnological applications [0.03%]
漆酶：微生物来源、生产、纯化及潜在的生物技术应用
Shraddha,Ravi Shekher,Simran Sehgal et al.
Shraddha et al.
Laccase belongs to the blue multicopper oxidases and participates in cross-linking of monomers, degradation of polymers, and ring cleavage of aromatic compounds. It is widely distributed in higher plants and fungi. It is present in Ascomyce...
Claudia Fernanda Dick,André Luiz Araújo Dos-Santos,José Roberto Meyer-Fernandes
Claudia Fernanda Dick
Cellular metabolism depends on the appropriate concentration of intracellular inorganic phosphate (Pi). Pi starvation-responsive genes appear to be involved in multiple metabolic pathways, implying a complex Pi regulation system in microorg...
Biosynthesis of galactofuranose in kinetoplastids: novel therapeutic targets for treating leishmaniasis and chagas' disease [0.03%]
毕氏原虫中半乳糖呋喃糖的生物合成：治疗利什曼病和查加斯病的新疗法目标
Michelle Oppenheimer,Ana L Valenciano,Pablo Sobrado
Michelle Oppenheimer
Cell surface proteins of parasites play a role in pathogenesis by modulating mammalian cell recognition and cell adhesion during infection. β-Galactofuranose (Galf) is an important component of glycoproteins and glycolipids found on the ce...
Towards Al-induced manganese-containing superoxide dismutase inactivation and conformational changes: an integrating study with docking simulations [0.03%]
基于对接模拟的阿尔法诱导的含锰超氧化物歧化酶失活及构象变化的整合研究
Jiang-Liu Yang,Shang-Jun Yin,Yue-Xiu Si et al.
Jiang-Liu Yang et al.
Superoxide dismutase (SOD, EC 1.15.1.1) plays an important antioxidant defense role in skins exposed to oxygen. We studied the inhibitory effects of Al(3+) on the activity and conformation of manganese-containing SOD (Mn-SOD). Mn-SOD was si...
Enzymatic biodiesel synthesis using a byproduct obtained from palm oil refining [0.03%]
利用从棕榈油精炼中获得的副产品进行酶法生物柴油合成
Igor Nascentes Dos Santos Corrêa,Susana Lorena de Souza,Marly Catran et al.
Igor Nascentes Dos Santos Corrêa et al.
An alternative route to produce biodiesel is based on esterification of free fatty acids present in byproducts obtained from vegetable oil refining, such as palm oil fatty acid distillate (PFAD). PFAD is a byproduct of the production of edi...
Chiral Pharmaceutical Intermediaries Obtained by Reduction of 2-Halo-1-(4-substituted phenyl)-ethanones Mediated by Geotrichum candidum CCT 1205 and Rhodotorula glutinis CCT 2182 [0.03%]
里氏木霉CCT 1205和红酵母CCT 2182介导的不对称还原合成手性药物中间体2-卤代-1-(4-取代苯基)乙酮类化合物
Lucídio C Fardelone,J Augusto R Rodrigues,Paulo J S Moran
Lucídio C Fardelone
Enantioselective reductions of p-R(1)-C(6)H(4)C(O)CH(2)R(2) (R(1) = Cl, Br, CH(3), OCH(3), NO(2) and R(2) = Br, Cl) mediated by Geotrichum candidum CCT 1205 and Rhodotorula glutinis CCT 2182 afforded the corresponding halohydrins with compl...
Chemical and physicochemical pretreatment of lignocellulosic biomass: a review [0.03%]
木质纤维素生物质的化学和物理化学预处理研究进展综述
Gary Brodeur,Elizabeth Yau,Kimberly Badal et al.
Gary Brodeur et al.
Overcoming the recalcitrance (resistance of plant cell walls to deconstruction) of lignocellulosic biomass is a key step in the production of fuels and chemicals. The recalcitrance is due to the highly crystalline structure of cellulose whi...