Towards Al-induced manganese-containing superoxide dismutase inactivation and conformational changes: an integrating study with docking simulations
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Superoxide dismutase (SOD, EC 1.15.1.1) plays an important antioxidant defense role in skins exposed to oxygen. We studied the inhibitory effects of Al(3+) on the activity and conformation of manganese-containing SOD (Mn-SOD). Mn-SOD was significantly inactiva... ...